CoP: Co-expressed Biological Processes

Microarray experiments to specifically-expressed genes

GSM ID GSM311287

Assay name Laser capture microdissected (LCM) embryo proper at the linear-cotyledon stage, biological replicate 1

GSE experiment GSE12403: Expression data from Arabidopsis seed compartments at the linear-cotyledon stage

Click Gene ID to show a list of GSM assays in which the gene are specifically expressed.

Std2 GX %ile Std GX Gene ID Repr. ID Gene name Functional description O.I. C.G. H.G. Other DB
1020.2 100.0 800.4 At1g04660 839454 glycine-rich protein F:molecular_function unknown;P:biological_process unknown;C:endomembrane system;MBOPFVA O.I. C.G. H.G.
593.6 100.0 256.6 At5g27200 832778 ACP5 (acyl carrier protein 5) encodes an acyl carrier protein O.I. C.G. H.G.
402.0 100.0 95.5 At1g67590 843080 remorin family protein F:DNA binding;P:biological_process unknown;C:nucleus;OPBMFVA O.I. C.G. H.G.
390.6 100.0 150.9 At5g01075 831885 beta-galactosidase F:beta-galactosidase activity;P:carbohydrate metabolic process;C:endomembrane system, beta-galactosidase complex;P O.I. C.G. H.G.
388.9 100.0 285.2 At3g57930 824962 unknown protein F:molecular_function unknown;P:biological_process unknown;C:unknown;MOFPBV O.I. C.G. H.G.
386.6 100.0 109.7 At5g13790 831224 AGL15 (AGAMOUS-LIKE 15) AGL15 (AGAMOUS-Like 15) is a member of the MADS domain family of regulatory factors. Although AGL15 is preferentially expressed during embryogenesis, AGL15 is also expressed in leaf primordia, shoot apical meristems and young floral buds, suggesting that AGL15 may play a role during post-germinative development. Transgenic plants that ectopically express AGL15 show delays in the transition to flowering, perianth abscission and senescence and fruit and seed maturation. O.I. C.G. H.G.
313.4 100.0 125.1 At3g14900 820719 unknown protein F:molecular_function unknown;P:biological_process unknown;C:chloroplast;MOFBPVA O.I. C.G. H.G.
303.8 100.0 75.5 At1g11420 837684 agenet domain-containing protein F:RNA binding;P:unknown;C:cellular_component unknown;PMOBAFV O.I. C.G. H.G.
246.3 100.0 73.0 At5g22810 832344 GDSL-motif lipase, putative F:lipase activity, hydrolase activity, acting on ester bonds, carboxylesterase activity;P:lipid metabolic process;C:endomembrane system;PBOFM O.I. C.G. H.G.
243.9 100.0 267.6 At5g40610 834060 glycerol-3-phosphate dehydrogenase (NAD+) / GPDH F:in 9 functions;P:oxidation reduction, glycerol-3-phosphate metabolic process, glycerol-3-phosphate catabolic process, carbohydrate metabolic process, metabolic process;C:chloroplast, glycerol-3-phosphate dehydrogenase complex, cytoplasm;BOMFPA O.I. C.G. H.G.
198.0 100.0 147.3 At1g73177 843651 BNS (BONSAI) The BONSAI gene encodes a protein with similarity to the APC13 component of the Anaphase Promoting Complex. Plants with lowered level of BONSAI expression, resulting from hypomethylation, RNAi knock-down, or a T-DNA insertion show some abnormalities in shoot and inflorescence development. O.I. C.G. H.G.
195.2 100.0 153.6 At1g15910 838161 XH/XS domain-containing protein / XS zinc finger domain-containing protein F:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;MOBFPAV O.I. C.G. H.G.
169.6 100.0 172.0 At2g11890 815664 adenylate cyclase adenylate cyclase O.I. C.G. H.G.
165.1 100.0 283.0 At2g37630 818340 AS1 (ASYMMETRIC LEAVES 1) Encodes a MYB-domain protein involved in specification of the leaf proximodistal axis. Mutation results in lobed and dissected leaves with a characteristic asymmetry. Homologous to the Antirrhinum PHANTASTICA (PHAN) and maize ROUGH SHEATH2 (RS2) genes Asymmetric placement of auxin response at the distal leaf tip precedes visible asymmetric leaf growth. Acts alongside AXR1 to exclude BP expression in leaves and with PIN1 to repress BP and promote lateral organ growth. Interacts physically with AS2 to form a complex that binds to the BP promoter and silences BP. O.I. C.G. H.G.
161.3 99.9 94.2 At4g00820 828002 iqd17 (IQ-domain 17) F:calmodulin binding;P:biological_process unknown;C:unknown;POMFVB O.I. C.G. H.G.
160.6 99.9 106.8 At3g51270 824290 ATP binding / catalytic/ protein serine/threonine kinase F:protein serine/threonine kinase activity, catalytic activity, ATP binding;P:protein amino acid phosphorylation;C:cellular_component unknown;MOFBPVA O.I. C.G. H.G.
158.1 99.9 142.7 At2g27470 817292 NF-YB11 (NUCLEAR FACTOR Y, SUBUNIT B11) F:transcription factor activity;P:regulation of transcription;C:intracellular;OMFBPVA O.I. C.G. H.G.
153.6 99.9 602.8 At3g17160 820973 unknown protein F:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;MOBFPVA O.I. C.G. H.G.
153.2 99.9 297.5 At1g72440 843576 EDA25 (embryo sac development arrest 25) F:unknown;P:polar nucleus fusion;C:endomembrane system;BOMFPVA O.I. C.G. H.G.
152.8 99.9 14.4 At2g36030 818176 unknown protein F:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;P O.I. C.G. H.G.
141.5 99.9 79.5 At5g23680 832433 sterile alpha motif (SAM) domain-containing protein F:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;MPOBFV O.I. C.G. H.G.
141.4 99.9 226.5 At5g60030 836125 unknown protein F:unknown;P:unknown;C:unknown;MOFBPVA O.I. C.G. H.G.
140.8 99.9 67.2 At2g42110 818811 unknown protein F:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;PO O.I. C.G. H.G.
137.9 99.9 142.4 At2g13690 815853 PRLI-interacting factor, putative F:transcription regulator activity;P:biological_process unknown;C:unknown;P O.I. C.G. H.G.
134.0 99.9 207.6 At2g41650 818763 unknown protein F:molecular_function unknown;P:biological_process unknown;C:chloroplast;P O.I. C.G. H.G.
133.7 99.9 146.2 At2g42190 818819 unknown protein F:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;MOFPVBA O.I. C.G. H.G.
132.7 99.9 120.0 At2g37400 818316 chloroplast lumen common family protein F:binding;P:biological_process unknown;C:mitochondrion, chloroplast thylakoid lumen, plastid, chloroplast envelope;BOAMPF O.I. C.G. H.G.
131.6 99.9 87.6 At1g23000 838908 heavy-metal-associated domain-containing protein F:metal ion binding;P:metal ion transport;C:cellular_component unknown;OPMFB O.I. C.G. H.G.
128.9 99.9 70.9 At3g44050 823523 kinesin motor protein-related F:microtubule motor activity, ATP binding;P:microtubule-based movement;C:microtubule associated complex, chloroplast;MOBFPAV O.I. C.G. H.G.
127.8 99.9 31.3 At4g26660 828773 - F:unknown;P:biological_process unknown;C:chloroplast;MOFBPAV O.I. C.G. H.G.
126.8 99.9 243.0 At3g17170 820974 RFC3 (REGULATOR OF FATTY-ACID COMPOSITION 3) F:structural constituent of ribosome;P:translation, ribosome biogenesis;C:ribosome, intracellular, chloroplast;MOBFPVA O.I. C.G. H.G.
118.0 99.9 154.6 At3g24490 822039 transcription factor F:transcription factor activity;P:regulation of transcription;C:cellular_component unknown;MOPFBV O.I. C.G. H.G.
115.8 99.9 91.7 At1g17140 838284 tropomyosin-related F:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;MOBFPAV O.I. C.G. H.G.
114.9 99.9 173.2 At1g65090 842817 unknown protein F:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;MOFPBV O.I. C.G. H.G.
114.5 99.9 23.3 At3g25440 822128 RNA binding F:RNA binding;P:biological_process unknown;C:chloroplast;PMOFVBA O.I. C.G. H.G.
114.4 99.9 180.5 At5g15530 831406 BCCP2 (BIOTIN CARBOXYL CARRIER PROTEIN 2) biotin carboxyl carrier protein isoform 2 (BCCP2) mRNA, O.I. C.G. H.G.
113.8 99.9 292.3 At2g34700 818035 pollen Ole e 1 allergen and extensin family protein F:molecular_function unknown;P:biological_process unknown;C:endomembrane system;P O.I. C.G. H.G.
113.5 99.9 93.9 At5g50740 835146 metal ion binding F:metal ion binding;P:metal ion transport;C:cellular_component unknown;POMBFV O.I. C.G. H.G.
111.9 99.9 48.1 At3g15560 - - O.I. C.G. H.G.
108.4 99.9 236.5 At1g15340 838103 MBD10 Protein containing methyl-CpG-binding domain.Has sequence similarity to human MBD proteins. O.I. C.G. H.G.
107.6 99.9 65.5 At5g57810 835890 TET15 (TETRASPANIN15) Member of TETRASPANIN family O.I. C.G. H.G.
106.1 99.9 64.9 At3g29310 822589 calmodulin-binding protein-related F:molecular_function unknown;P:biological_process unknown;C:plasma membrane;MOFPBV O.I. C.G. H.G.
103.9 99.9 72.3 At5g50770 835149 AtHSD6 (hydroxysteroid dehydrogenase 6) F:oxidoreductase activity, binding, catalytic activity;P:metabolic process;C:endomembrane system;BOMFPAV O.I. C.G. H.G.
100.6 99.9 117.4 At5g48360 834889 formin homology 2 domain-containing protein / FH2 domain-containing protein F:actin binding;P:cellular component organization, actin cytoskeleton organization;C:unknown;MPOFVBA O.I. C.G. H.G.
99.3 99.9 209.3 At3g58660 825035 60S ribosomal protein-related F:structural constituent of ribosome, RNA binding;P:translation, RNA processing;C:nucleolus, membrane;MOFPBAV O.I. C.G. H.G.
98.5 99.9 75.1 At3g49240 824085 emb1796 (embryo defective 1796) F:ATP binding;P:embryonic development ending in seed dormancy;C:mitochondrion, chloroplast;POMFBA O.I. C.G. H.G.
96.1 99.9 79.4 At4g00270 827164 DNA-binding storekeeper protein-related F:transcription regulator activity;P:biological_process unknown;C:chloroplast;POM O.I. C.G. H.G.
95.3 99.9 334.8 At1g47970 841215 unknown protein F:molecular_function unknown;P:biological_process unknown;C:cytosol;MOFBPVA O.I. C.G. H.G.
95.3 99.9 115.0 At5g23890 832454 - F:unknown;P:unknown;C:mitochondrion, chloroplast thylakoid membrane, chloroplast, plastid, chloroplast envelope;MOBFPAV O.I. C.G. H.G.
94.7 99.9 52.5 At4g12700 826882 unknown protein F:molecular_function unknown;P:biological_process unknown;C:unknown;PO O.I. C.G. H.G.
93.8 99.9 271.8 At2g07711 3768480 - F:unknown;P:unknown;C:unknown O.I. C.G. H.G.
93.0 99.9 17.5 At3g19050 821439 POK2 (PHRAGMOPLAST ORIENTING KINESIN 2) PHRAGMOPLAST ORIENTING KINESIN 2 is one of the two Arabidopsis homologs isolated in yeast two-hybrid screen for interaction partners of maize gene TANGLED1 (TAN1). Based on sequence homology in their motor domains, POK1 and POK2 belong to the kinesin-12 class which also includes the well-characterized group of phragmoplast-associated kinesins AtPAKRPs. Both kinesins are composed of an N-terminal motor domain throughout the entire C terminus and putative cargo binding tail domains. The expression domains for POK2 constructs were broader than those for POK1; both are expressed in tissues enriched for dividing cells. The phenotype of pok1/pok2 double mutants strongly resembles that of maize tan1 mutants, characterized by misoriented mitotic cytoskeletal arrays and misplaced cell walls. O.I. C.G. H.G.
92.8 99.9 229.5 At4g23800 828480 high mobility group (HMG1/2) family protein F:transcription factor activity;P:unknown;C:nucleus, chloroplast;MOBFPAV O.I. C.G. H.G.
90.3 99.9 68.5 At5g47690 834820 binding F:binding;P:biological_process unknown;C:mitochondrion, nucleus, chloroplast;MOFPBVA O.I. C.G. H.G.
89.0 99.9 37.6 At1g03830 839398 guanylate-binding family protein F:GTP binding, GTPase activity;P:immune response;C:cellular_component unknown;MOBFPAV O.I. C.G. H.G.
88.5 99.9 14.1 At5g16790 831542 - F:unknown;P:unknown;C:unknown;MOFBPVA O.I. C.G. H.G.
86.3 99.9 76.9 At1g06420 837153 unknown protein F:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;OMFPB O.I. C.G. H.G.
85.9 99.9 158.7 At3g07780 819969 OBE1 (OBERON1) Encodes a nuclear PHD finger protein that is functionally redundant with OBE2 and plays an important role in the maintenance and/or establishment of the root and shoot apical meristems. O.I. C.G. H.G.
85.7 99.9 180.3 At2g25650 817106 DNA-binding storekeeper protein-related F:transcription regulator activity;P:biological_process unknown;C:cellular_component unknown;OMFPBVA O.I. C.G. H.G.
85.3 99.9 379.5 At5g38160 833796 protease inhibitor/seed storage/lipid transfer protein (LTP) family protein F:lipid binding;P:lipid transport;C:endomembrane system;P O.I. C.G. H.G.
85.3 99.9 74.6 At2g41070 818706 EEL (ENHANCED EM LEVEL) Transcription factor homologous to ABI5. Regulates AtEm1 expression by binding directly at the AtEm1 promoter. Located in the nucleus and expressed during seed maturation in the cotyledons and later in the whole embryo. O.I. C.G. H.G.
83.5 99.9 89.5 At3g19650 821502 cyclin-related F:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;MOFPBV O.I. C.G. H.G.
83.4 99.9 101.6 At1g63470 842653 DNA-binding family protein F:DNA binding;P:biological_process unknown;C:cellular_component unknown;PMFBO O.I. C.G. H.G.
83.0 99.9 132.5 At2g40650 818660 pre-mRNA splicing factor PRP38 family protein F:binding;P:RNA processing;C:cellular_component unknown;MBOFPVA O.I. C.G. H.G.
81.6 99.9 281.1 At5g61030 836224 GR-RBP3 (glycine-rich RNA-binding protein 3) encodes a glycine-rich RNA binding protein. Gene expression is induced by cold. O.I. C.G. H.G.
80.4 99.9 66.0 At1g78430 844179 - F:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;MOBFPAV O.I. C.G. H.G.
76.1 99.9 87.9 At4g13050 826919 acyl-(acyl carrier protein) thioesterase, putative / acyl-ACP thioesterase, putative / oleoyl-(acyl-carrier protein) hydrolase, putative / S-acyl fatty acid synthase thioesterase, putative F:acyl carrier activity;P:fatty acid biosynthetic process;C:chloroplast;BPOM O.I. C.G. H.G.
75.1 99.9 105.5 At1g68790 843210 LINC3 (LITTLE NUCLEI3) F:unknown;P:biological_process unknown;C:nucleolus;MOBFPAV O.I. C.G. H.G.
73.6 99.9 74.0 At2g37080 818284 myosin heavy chain-related F:unknown;P:unknown;C:chloroplast;MOBFPAV O.I. C.G. H.G.
73.2 99.9 102.5 At5g55660 835660 - F:unknown;P:unknown;C:mitochondrion;MOFBPVA O.I. C.G. H.G.
72.7 99.9 154.9 At3g05600 819726 epoxide hydrolase, putative F:epoxide hydrolase activity, catalytic activity;P:unknown;C:unknown;BOMPFA O.I. C.G. H.G.
72.4 99.9 170.3 At1g77590 844094 LACS9 (LONG CHAIN ACYL-COA SYNTHETASE 9) Encodes major plastidic long chain acyl-CoA synthetase with a slight substrate preference of oleic acid over any of the other fatty acids. O.I. C.G. H.G.
72.1 99.9 54.6 At5g14750 831327 ATMYB66 (MYB DOMAIN PROTEIN 66) Encodes a MyB-related protein containing R2 and R3 repeats, involved in root and hypocotyl epidermal cell fate determination. Loss of function mutations make extra root hairs. Nuclear localized protein is a positive regulator for expression of CAPRICE (CPC). O.I. C.G. H.G.
71.9 99.9 69.9 At3g51280 824291 male sterility MS5, putative F:binding;P:unknown;C:cellular_component unknown;OBPAF O.I. C.G. H.G.
69.4 99.9 180.9 At5g61310 836252 cytochrome c oxidase subunit Vc, putative / COX5C, putative F:cytochrome-c oxidase activity;P:unknown;C:mitochondrial respiratory chain, endomembrane system;P O.I. C.G. H.G.
69.1 99.9 19.4 At5g52950 835372 unknown protein F:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;POBMF O.I. C.G. H.G.
68.4 99.9 105.7 At4g10750 826669 HpcH/HpaI aldolase family protein F:carbon-carbon lyase activity, catalytic activity;P:in 8 processes;C:mitochondrion, chloroplast;BOFPA O.I. C.G. H.G.
68.4 99.9 94.1 At1g21560 838757 unknown protein F:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;PBM O.I. C.G. H.G.
68.1 99.9 127.1 At3g09980 820159 unknown protein F:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;MOBFPAV O.I. C.G. H.G.
68.0 99.9 117.1 At2g45860 819194 unknown protein F:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;P O.I. C.G. H.G.
67.0 99.8 82.2 At3g45450 823685 Clp amino terminal domain-containing protein F:protein binding, ATP binding;P:protein metabolic process;C:unknown;BOPFAMV O.I. C.G. H.G.
66.6 99.8 54.9 At4g14695 827120 unknown protein F:unknown;P:biological_process unknown;C:mitochondrion;MFPO O.I. C.G. H.G.
66.4 99.8 44.8 At3g14980 820727 PHD finger transcription factor, putative F:protein binding, DNA binding, zinc ion binding, N-acetyltransferase activity;P:regulation of transcription, DNA-dependent, metabolic process;C:nucleus;MPFOBA O.I. C.G. H.G.
66.3 99.8 42.8 At1g75190 843856 unknown protein F:molecular_function unknown;P:biological_process unknown;C:unknown;MOFVPBA O.I. C.G. H.G.
65.8 99.8 38.8 At3g05830 819752 - Encodes alpha-helical IF (intermediate filament)-like protein. O.I. C.G. H.G.
65.5 99.8 63.4 At2g38370 818418 unknown protein F:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;MOBFPAV O.I. C.G. H.G.
65.2 99.8 49.6 At1g54160 841856 NF-YA5 (NUCLEAR FACTOR Y, SUBUNIT A5) Encodes a member of the CCAAT-binding transcription factor (CBF-B/NF-YA) family. Expression is upregulated in response to ABA and drought. This regulation appears to be mediated by MIR169A which is downregulated in response to drought. NFYA5 is a target of MIR169A. Loss of function mutations are hypersensitive to drought. O.I. C.G. H.G.
64.8 99.8 43.8 At2g47500 819363 ATP binding / microtubule motor F:microtubule motor activity, ATP binding;P:microtubule-based movement;C:microtubule associated complex;MOFP O.I. C.G. H.G.
64.2 99.8 51.7 At1g03780 839140 targeting protein-related Homolog of vertebrate TPX2. Protein has three domains involved in nuclear targeting, one in nuclear export and two in microtubule binding. Involved in mitotic spindle assembly during late prophase and early prometaphase. O.I. C.G. H.G.
63.7 99.8 46.5 At5g51600 835234 PLE (PLEIADE) Mutant has defective roots. Essential for giant cell ontogenesis. Role in organizing the mitotic microtubule array during both early and late mitosis in all plant organs. O.I. C.G. H.G.
63.4 99.8 27.5 At4g13690 827003 unknown protein F:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;POBM O.I. C.G. H.G.
63.4 99.8 20.8 At1g32760 840170 glutaredoxin family protein F:electron carrier activity, protein disulfide oxidoreductase activity;P:cell redox homeostasis;C:chloroplast;PMOBF O.I. C.G. H.G.
63.1 99.8 38.5 At5g25580 832633 - F:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;MPFOBV O.I. C.G. H.G.
63.0 99.8 50.5 At5g16950 831558 unknown protein F:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;P O.I. C.G. H.G.
62.2 99.8 62.3 At2g07690 815415 minichromosome maintenance family protein / MCM family protein Member of the minichromosome maintenance complex, involved in DNA replication initiation. Abundant in proliferating and endocycling tissues. Localized in the nucleus during G1, S and G2 phases of the cell cycle, and are released into the cytoplasmic compartment during mitosis. Binds chromatin. O.I. C.G. H.G.
61.8 99.8 187.3 At1g15200 838086 protein-protein interaction regulator family protein F:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;MOFBPVA O.I. C.G. H.G.
61.7 99.8 75.8 At4g36920 829845 AP2 (APETALA 2) Encodes a floral homeotic gene, a member of the AP2/EREBP (ethylene responsive element binding protein) class of transcription factors and is involved in the specification of floral organ identity, establishment of floral meristem identity, suppression of floral meristem indeterminancy, and development of the ovule and seed coat. AP2 also has a role in controlling seed mass. Dominant negative allele I28, revealed a function in meristem maintenance-mutant meristems are smaller than normal siblings. AP2 appears to act on the WUS-CLV pathway in an AG independent manner. O.I. C.G. H.G.
61.6 99.8 145.5 At1g71691 843496 GDSL-motif lipase/hydrolase family protein F:hydrolase activity, acting on ester bonds, carboxylesterase activity;P:lipid metabolic process;C:unknown;PBFOM O.I. C.G. H.G.
61.4 99.8 161.1 At2g07707 815382 hydrogen ion transmembrane transporter/ hydrolase, acting on acid anhydrides, catalyzing transmembrane movement of substances F:hydrogen ion transmembrane transporter activity, hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;P:ATP synthesis coupled proton transport;C:mitochondrion, vacuole, membrane;PO O.I. C.G. H.G.
61.1 99.8 149.9 At3g02760 820930 ATP binding / aminoacyl-tRNA ligase/ histidine-tRNA ligase/ nucleotide binding F:histidine-tRNA ligase activity, aminoacyl-tRNA ligase activity, nucleotide binding, ATP binding;P:histidyl-tRNA aminoacylation, translation, tRNA aminoacylation for protein translation;C:chloroplast, cytoplasm;OBMFAP O.I. C.G. H.G.

Std2 GX	%ile	Std GX	Gene ID	Repr. ID	Gene name	Functional description	O.I.	C.G.	H.G.
1020.2	100.0	800.4	At1g04660	839454	glycine-rich protein	F:molecular_function unknown;P:biological_process unknown;C:endomembrane system;MBOPFVA	O.I.	C.G.	H.G.
593.6	100.0	256.6	At5g27200	832778	ACP5 (acyl carrier protein 5)	encodes an acyl carrier protein	O.I.	C.G.	H.G.
402.0	100.0	95.5	At1g67590	843080	remorin family protein	F:DNA binding;P:biological_process unknown;C:nucleus;OPBMFVA	O.I.	C.G.	H.G.
390.6	100.0	150.9	At5g01075	831885	beta-galactosidase	F:beta-galactosidase activity;P:carbohydrate metabolic process;C:endomembrane system, beta-galactosidase complex;P	O.I.	C.G.	H.G.
388.9	100.0	285.2	At3g57930	824962	unknown protein	F:molecular_function unknown;P:biological_process unknown;C:unknown;MOFPBV	O.I.	C.G.	H.G.
386.6	100.0	109.7	At5g13790	831224	AGL15 (AGAMOUS-LIKE 15)	AGL15 (AGAMOUS-Like 15) is a member of the MADS domain family of regulatory factors. Although AGL15 is preferentially expressed during embryogenesis, AGL15 is also expressed in leaf primordia, shoot apical meristems and young floral buds, suggesting that AGL15 may play a role during post-germinative development. Transgenic plants that ectopically express AGL15 show delays in the transition to flowering, perianth abscission and senescence and fruit and seed maturation.	O.I.	C.G.	H.G.
313.4	100.0	125.1	At3g14900	820719	unknown protein	F:molecular_function unknown;P:biological_process unknown;C:chloroplast;MOFBPVA	O.I.	C.G.	H.G.
303.8	100.0	75.5	At1g11420	837684	agenet domain-containing protein	F:RNA binding;P:unknown;C:cellular_component unknown;PMOBAFV	O.I.	C.G.	H.G.
246.3	100.0	73.0	At5g22810	832344	GDSL-motif lipase, putative	F:lipase activity, hydrolase activity, acting on ester bonds, carboxylesterase activity;P:lipid metabolic process;C:endomembrane system;PBOFM	O.I.	C.G.	H.G.
243.9	100.0	267.6	At5g40610	834060	glycerol-3-phosphate dehydrogenase (NAD+) / GPDH	F:in 9 functions;P:oxidation reduction, glycerol-3-phosphate metabolic process, glycerol-3-phosphate catabolic process, carbohydrate metabolic process, metabolic process;C:chloroplast, glycerol-3-phosphate dehydrogenase complex, cytoplasm;BOMFPA	O.I.	C.G.	H.G.
198.0	100.0	147.3	At1g73177	843651	BNS (BONSAI)	The BONSAI gene encodes a protein with similarity to the APC13 component of the Anaphase Promoting Complex. Plants with lowered level of BONSAI expression, resulting from hypomethylation, RNAi knock-down, or a T-DNA insertion show some abnormalities in shoot and inflorescence development.	O.I.	C.G.	H.G.
195.2	100.0	153.6	At1g15910	838161	XH/XS domain-containing protein / XS zinc finger domain-containing protein	F:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;MOBFPAV	O.I.	C.G.	H.G.
169.6	100.0	172.0	At2g11890	815664	adenylate cyclase	adenylate cyclase	O.I.	C.G.	H.G.
165.1	100.0	283.0	At2g37630	818340	AS1 (ASYMMETRIC LEAVES 1)	Encodes a MYB-domain protein involved in specification of the leaf proximodistal axis. Mutation results in lobed and dissected leaves with a characteristic asymmetry. Homologous to the Antirrhinum PHANTASTICA (PHAN) and maize ROUGH SHEATH2 (RS2) genes Asymmetric placement of auxin response at the distal leaf tip precedes visible asymmetric leaf growth. Acts alongside AXR1 to exclude BP expression in leaves and with PIN1 to repress BP and promote lateral organ growth. Interacts physically with AS2 to form a complex that binds to the BP promoter and silences BP.	O.I.	C.G.	H.G.
161.3	99.9	94.2	At4g00820	828002	iqd17 (IQ-domain 17)	F:calmodulin binding;P:biological_process unknown;C:unknown;POMFVB	O.I.	C.G.	H.G.
160.6	99.9	106.8	At3g51270	824290	ATP binding / catalytic/ protein serine/threonine kinase	F:protein serine/threonine kinase activity, catalytic activity, ATP binding;P:protein amino acid phosphorylation;C:cellular_component unknown;MOFBPVA	O.I.	C.G.	H.G.
158.1	99.9	142.7	At2g27470	817292	NF-YB11 (NUCLEAR FACTOR Y, SUBUNIT B11)	F:transcription factor activity;P:regulation of transcription;C:intracellular;OMFBPVA	O.I.	C.G.	H.G.
153.6	99.9	602.8	At3g17160	820973	unknown protein	F:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;MOBFPVA	O.I.	C.G.	H.G.
153.2	99.9	297.5	At1g72440	843576	EDA25 (embryo sac development arrest 25)	F:unknown;P:polar nucleus fusion;C:endomembrane system;BOMFPVA	O.I.	C.G.	H.G.
152.8	99.9	14.4	At2g36030	818176	unknown protein	F:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;P	O.I.	C.G.	H.G.
141.5	99.9	79.5	At5g23680	832433	sterile alpha motif (SAM) domain-containing protein	F:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;MPOBFV	O.I.	C.G.	H.G.
141.4	99.9	226.5	At5g60030	836125	unknown protein	F:unknown;P:unknown;C:unknown;MOFBPVA	O.I.	C.G.	H.G.
140.8	99.9	67.2	At2g42110	818811	unknown protein	F:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;PO	O.I.	C.G.	H.G.
137.9	99.9	142.4	At2g13690	815853	PRLI-interacting factor, putative	F:transcription regulator activity;P:biological_process unknown;C:unknown;P	O.I.	C.G.	H.G.
134.0	99.9	207.6	At2g41650	818763	unknown protein	F:molecular_function unknown;P:biological_process unknown;C:chloroplast;P	O.I.	C.G.	H.G.
133.7	99.9	146.2	At2g42190	818819	unknown protein	F:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;MOFPVBA	O.I.	C.G.	H.G.
132.7	99.9	120.0	At2g37400	818316	chloroplast lumen common family protein	F:binding;P:biological_process unknown;C:mitochondrion, chloroplast thylakoid lumen, plastid, chloroplast envelope;BOAMPF	O.I.	C.G.	H.G.
131.6	99.9	87.6	At1g23000	838908	heavy-metal-associated domain-containing protein	F:metal ion binding;P:metal ion transport;C:cellular_component unknown;OPMFB	O.I.	C.G.	H.G.
128.9	99.9	70.9	At3g44050	823523	kinesin motor protein-related	F:microtubule motor activity, ATP binding;P:microtubule-based movement;C:microtubule associated complex, chloroplast;MOBFPAV	O.I.	C.G.	H.G.
127.8	99.9	31.3	At4g26660	828773	-	F:unknown;P:biological_process unknown;C:chloroplast;MOFBPAV	O.I.	C.G.	H.G.
126.8	99.9	243.0	At3g17170	820974	RFC3 (REGULATOR OF FATTY-ACID COMPOSITION 3)	F:structural constituent of ribosome;P:translation, ribosome biogenesis;C:ribosome, intracellular, chloroplast;MOBFPVA	O.I.	C.G.	H.G.
118.0	99.9	154.6	At3g24490	822039	transcription factor	F:transcription factor activity;P:regulation of transcription;C:cellular_component unknown;MOPFBV	O.I.	C.G.	H.G.
115.8	99.9	91.7	At1g17140	838284	tropomyosin-related	F:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;MOBFPAV	O.I.	C.G.	H.G.
114.9	99.9	173.2	At1g65090	842817	unknown protein	F:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;MOFPBV	O.I.	C.G.	H.G.
114.5	99.9	23.3	At3g25440	822128	RNA binding	F:RNA binding;P:biological_process unknown;C:chloroplast;PMOFVBA	O.I.	C.G.	H.G.
114.4	99.9	180.5	At5g15530	831406	BCCP2 (BIOTIN CARBOXYL CARRIER PROTEIN 2)	biotin carboxyl carrier protein isoform 2 (BCCP2) mRNA,	O.I.	C.G.	H.G.
113.8	99.9	292.3	At2g34700	818035	pollen Ole e 1 allergen and extensin family protein	F:molecular_function unknown;P:biological_process unknown;C:endomembrane system;P	O.I.	C.G.	H.G.
113.5	99.9	93.9	At5g50740	835146	metal ion binding	F:metal ion binding;P:metal ion transport;C:cellular_component unknown;POMBFV	O.I.	C.G.	H.G.
111.9	99.9	48.1	At3g15560		-	-	O.I.	C.G.	H.G.
108.4	99.9	236.5	At1g15340	838103	MBD10	Protein containing methyl-CpG-binding domain.Has sequence similarity to human MBD proteins.	O.I.	C.G.	H.G.
107.6	99.9	65.5	At5g57810	835890	TET15 (TETRASPANIN15)	Member of TETRASPANIN family	O.I.	C.G.	H.G.
106.1	99.9	64.9	At3g29310	822589	calmodulin-binding protein-related	F:molecular_function unknown;P:biological_process unknown;C:plasma membrane;MOFPBV	O.I.	C.G.	H.G.
103.9	99.9	72.3	At5g50770	835149	AtHSD6 (hydroxysteroid dehydrogenase 6)	F:oxidoreductase activity, binding, catalytic activity;P:metabolic process;C:endomembrane system;BOMFPAV	O.I.	C.G.	H.G.
100.6	99.9	117.4	At5g48360	834889	formin homology 2 domain-containing protein / FH2 domain-containing protein	F:actin binding;P:cellular component organization, actin cytoskeleton organization;C:unknown;MPOFVBA	O.I.	C.G.	H.G.
99.3	99.9	209.3	At3g58660	825035	60S ribosomal protein-related	F:structural constituent of ribosome, RNA binding;P:translation, RNA processing;C:nucleolus, membrane;MOFPBAV	O.I.	C.G.	H.G.
98.5	99.9	75.1	At3g49240	824085	emb1796 (embryo defective 1796)	F:ATP binding;P:embryonic development ending in seed dormancy;C:mitochondrion, chloroplast;POMFBA	O.I.	C.G.	H.G.
96.1	99.9	79.4	At4g00270	827164	DNA-binding storekeeper protein-related	F:transcription regulator activity;P:biological_process unknown;C:chloroplast;POM	O.I.	C.G.	H.G.
95.3	99.9	334.8	At1g47970	841215	unknown protein	F:molecular_function unknown;P:biological_process unknown;C:cytosol;MOFBPVA	O.I.	C.G.	H.G.
95.3	99.9	115.0	At5g23890	832454	-	F:unknown;P:unknown;C:mitochondrion, chloroplast thylakoid membrane, chloroplast, plastid, chloroplast envelope;MOBFPAV	O.I.	C.G.	H.G.
94.7	99.9	52.5	At4g12700	826882	unknown protein	F:molecular_function unknown;P:biological_process unknown;C:unknown;PO	O.I.	C.G.	H.G.
93.8	99.9	271.8	At2g07711	3768480	-	F:unknown;P:unknown;C:unknown	O.I.	C.G.	H.G.
93.0	99.9	17.5	At3g19050	821439	POK2 (PHRAGMOPLAST ORIENTING KINESIN 2)	PHRAGMOPLAST ORIENTING KINESIN 2 is one of the two Arabidopsis homologs isolated in yeast two-hybrid screen for interaction partners of maize gene TANGLED1 (TAN1). Based on sequence homology in their motor domains, POK1 and POK2 belong to the kinesin-12 class which also includes the well-characterized group of phragmoplast-associated kinesins AtPAKRPs. Both kinesins are composed of an N-terminal motor domain throughout the entire C terminus and putative cargo binding tail domains. The expression domains for POK2 constructs were broader than those for POK1; both are expressed in tissues enriched for dividing cells. The phenotype of pok1/pok2 double mutants strongly resembles that of maize tan1 mutants, characterized by misoriented mitotic cytoskeletal arrays and misplaced cell walls.	O.I.	C.G.	H.G.
92.8	99.9	229.5	At4g23800	828480	high mobility group (HMG1/2) family protein	F:transcription factor activity;P:unknown;C:nucleus, chloroplast;MOBFPAV	O.I.	C.G.	H.G.
90.3	99.9	68.5	At5g47690	834820	binding	F:binding;P:biological_process unknown;C:mitochondrion, nucleus, chloroplast;MOFPBVA	O.I.	C.G.	H.G.
89.0	99.9	37.6	At1g03830	839398	guanylate-binding family protein	F:GTP binding, GTPase activity;P:immune response;C:cellular_component unknown;MOBFPAV	O.I.	C.G.	H.G.
88.5	99.9	14.1	At5g16790	831542	-	F:unknown;P:unknown;C:unknown;MOFBPVA	O.I.	C.G.	H.G.
86.3	99.9	76.9	At1g06420	837153	unknown protein	F:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;OMFPB	O.I.	C.G.	H.G.
85.9	99.9	158.7	At3g07780	819969	OBE1 (OBERON1)	Encodes a nuclear PHD finger protein that is functionally redundant with OBE2 and plays an important role in the maintenance and/or establishment of the root and shoot apical meristems.	O.I.	C.G.	H.G.
85.7	99.9	180.3	At2g25650	817106	DNA-binding storekeeper protein-related	F:transcription regulator activity;P:biological_process unknown;C:cellular_component unknown;OMFPBVA	O.I.	C.G.	H.G.
85.3	99.9	379.5	At5g38160	833796	protease inhibitor/seed storage/lipid transfer protein (LTP) family protein	F:lipid binding;P:lipid transport;C:endomembrane system;P	O.I.	C.G.	H.G.
85.3	99.9	74.6	At2g41070	818706	EEL (ENHANCED EM LEVEL)	Transcription factor homologous to ABI5. Regulates AtEm1 expression by binding directly at the AtEm1 promoter. Located in the nucleus and expressed during seed maturation in the cotyledons and later in the whole embryo.	O.I.	C.G.	H.G.
83.5	99.9	89.5	At3g19650	821502	cyclin-related	F:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;MOFPBV	O.I.	C.G.	H.G.
83.4	99.9	101.6	At1g63470	842653	DNA-binding family protein	F:DNA binding;P:biological_process unknown;C:cellular_component unknown;PMFBO	O.I.	C.G.	H.G.
83.0	99.9	132.5	At2g40650	818660	pre-mRNA splicing factor PRP38 family protein	F:binding;P:RNA processing;C:cellular_component unknown;MBOFPVA	O.I.	C.G.	H.G.
81.6	99.9	281.1	At5g61030	836224	GR-RBP3 (glycine-rich RNA-binding protein 3)	encodes a glycine-rich RNA binding protein. Gene expression is induced by cold.	O.I.	C.G.	H.G.
80.4	99.9	66.0	At1g78430	844179	-	F:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;MOBFPAV	O.I.	C.G.	H.G.
76.1	99.9	87.9	At4g13050	826919	acyl-(acyl carrier protein) thioesterase, putative / acyl-ACP thioesterase, putative / oleoyl-(acyl-carrier protein) hydrolase, putative / S-acyl fatty acid synthase thioesterase, putative	F:acyl carrier activity;P:fatty acid biosynthetic process;C:chloroplast;BPOM	O.I.	C.G.	H.G.
75.1	99.9	105.5	At1g68790	843210	LINC3 (LITTLE NUCLEI3)	F:unknown;P:biological_process unknown;C:nucleolus;MOBFPAV	O.I.	C.G.	H.G.
73.6	99.9	74.0	At2g37080	818284	myosin heavy chain-related	F:unknown;P:unknown;C:chloroplast;MOBFPAV	O.I.	C.G.	H.G.
73.2	99.9	102.5	At5g55660	835660	-	F:unknown;P:unknown;C:mitochondrion;MOFBPVA	O.I.	C.G.	H.G.
72.7	99.9	154.9	At3g05600	819726	epoxide hydrolase, putative	F:epoxide hydrolase activity, catalytic activity;P:unknown;C:unknown;BOMPFA	O.I.	C.G.	H.G.
72.4	99.9	170.3	At1g77590	844094	LACS9 (LONG CHAIN ACYL-COA SYNTHETASE 9)	Encodes major plastidic long chain acyl-CoA synthetase with a slight substrate preference of oleic acid over any of the other fatty acids.	O.I.	C.G.	H.G.
72.1	99.9	54.6	At5g14750	831327	ATMYB66 (MYB DOMAIN PROTEIN 66)	Encodes a MyB-related protein containing R2 and R3 repeats, involved in root and hypocotyl epidermal cell fate determination. Loss of function mutations make extra root hairs. Nuclear localized protein is a positive regulator for expression of CAPRICE (CPC).	O.I.	C.G.	H.G.
71.9	99.9	69.9	At3g51280	824291	male sterility MS5, putative	F:binding;P:unknown;C:cellular_component unknown;OBPAF	O.I.	C.G.	H.G.
69.4	99.9	180.9	At5g61310	836252	cytochrome c oxidase subunit Vc, putative / COX5C, putative	F:cytochrome-c oxidase activity;P:unknown;C:mitochondrial respiratory chain, endomembrane system;P	O.I.	C.G.	H.G.
69.1	99.9	19.4	At5g52950	835372	unknown protein	F:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;POBMF	O.I.	C.G.	H.G.
68.4	99.9	105.7	At4g10750	826669	HpcH/HpaI aldolase family protein	F:carbon-carbon lyase activity, catalytic activity;P:in 8 processes;C:mitochondrion, chloroplast;BOFPA	O.I.	C.G.	H.G.
68.4	99.9	94.1	At1g21560	838757	unknown protein	F:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;PBM	O.I.	C.G.	H.G.
68.1	99.9	127.1	At3g09980	820159	unknown protein	F:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;MOBFPAV	O.I.	C.G.	H.G.
68.0	99.9	117.1	At2g45860	819194	unknown protein	F:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;P	O.I.	C.G.	H.G.
67.0	99.8	82.2	At3g45450	823685	Clp amino terminal domain-containing protein	F:protein binding, ATP binding;P:protein metabolic process;C:unknown;BOPFAMV	O.I.	C.G.	H.G.
66.6	99.8	54.9	At4g14695	827120	unknown protein	F:unknown;P:biological_process unknown;C:mitochondrion;MFPO	O.I.	C.G.	H.G.
66.4	99.8	44.8	At3g14980	820727	PHD finger transcription factor, putative	F:protein binding, DNA binding, zinc ion binding, N-acetyltransferase activity;P:regulation of transcription, DNA-dependent, metabolic process;C:nucleus;MPFOBA	O.I.	C.G.	H.G.
66.3	99.8	42.8	At1g75190	843856	unknown protein	F:molecular_function unknown;P:biological_process unknown;C:unknown;MOFVPBA	O.I.	C.G.	H.G.
65.8	99.8	38.8	At3g05830	819752	-	Encodes alpha-helical IF (intermediate filament)-like protein.	O.I.	C.G.	H.G.
65.5	99.8	63.4	At2g38370	818418	unknown protein	F:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;MOBFPAV	O.I.	C.G.	H.G.
65.2	99.8	49.6	At1g54160	841856	NF-YA5 (NUCLEAR FACTOR Y, SUBUNIT A5)	Encodes a member of the CCAAT-binding transcription factor (CBF-B/NF-YA) family. Expression is upregulated in response to ABA and drought. This regulation appears to be mediated by MIR169A which is downregulated in response to drought. NFYA5 is a target of MIR169A. Loss of function mutations are hypersensitive to drought.	O.I.	C.G.	H.G.
64.8	99.8	43.8	At2g47500	819363	ATP binding / microtubule motor	F:microtubule motor activity, ATP binding;P:microtubule-based movement;C:microtubule associated complex;MOFP	O.I.	C.G.	H.G.
64.2	99.8	51.7	At1g03780	839140	targeting protein-related	Homolog of vertebrate TPX2. Protein has three domains involved in nuclear targeting, one in nuclear export and two in microtubule binding. Involved in mitotic spindle assembly during late prophase and early prometaphase.	O.I.	C.G.	H.G.
63.7	99.8	46.5	At5g51600	835234	PLE (PLEIADE)	Mutant has defective roots. Essential for giant cell ontogenesis. Role in organizing the mitotic microtubule array during both early and late mitosis in all plant organs.	O.I.	C.G.	H.G.
63.4	99.8	27.5	At4g13690	827003	unknown protein	F:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;POBM	O.I.	C.G.	H.G.
63.4	99.8	20.8	At1g32760	840170	glutaredoxin family protein	F:electron carrier activity, protein disulfide oxidoreductase activity;P:cell redox homeostasis;C:chloroplast;PMOBF	O.I.	C.G.	H.G.
63.1	99.8	38.5	At5g25580	832633	-	F:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;MPFOBV	O.I.	C.G.	H.G.
63.0	99.8	50.5	At5g16950	831558	unknown protein	F:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;P	O.I.	C.G.	H.G.
62.2	99.8	62.3	At2g07690	815415	minichromosome maintenance family protein / MCM family protein	Member of the minichromosome maintenance complex, involved in DNA replication initiation. Abundant in proliferating and endocycling tissues. Localized in the nucleus during G1, S and G2 phases of the cell cycle, and are released into the cytoplasmic compartment during mitosis. Binds chromatin.	O.I.	C.G.	H.G.
61.8	99.8	187.3	At1g15200	838086	protein-protein interaction regulator family protein	F:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;MOFBPVA	O.I.	C.G.	H.G.
61.7	99.8	75.8	At4g36920	829845	AP2 (APETALA 2)	Encodes a floral homeotic gene, a member of the AP2/EREBP (ethylene responsive element binding protein) class of transcription factors and is involved in the specification of floral organ identity, establishment of floral meristem identity, suppression of floral meristem indeterminancy, and development of the ovule and seed coat. AP2 also has a role in controlling seed mass. Dominant negative allele I28, revealed a function in meristem maintenance-mutant meristems are smaller than normal siblings. AP2 appears to act on the WUS-CLV pathway in an AG independent manner.	O.I.	C.G.	H.G.
61.6	99.8	145.5	At1g71691	843496	GDSL-motif lipase/hydrolase family protein	F:hydrolase activity, acting on ester bonds, carboxylesterase activity;P:lipid metabolic process;C:unknown;PBFOM	O.I.	C.G.	H.G.
61.4	99.8	161.1	At2g07707	815382	hydrogen ion transmembrane transporter/ hydrolase, acting on acid anhydrides, catalyzing transmembrane movement of substances	F:hydrogen ion transmembrane transporter activity, hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;P:ATP synthesis coupled proton transport;C:mitochondrion, vacuole, membrane;PO	O.I.	C.G.	H.G.
61.1	99.8	149.9	At3g02760	820930	ATP binding / aminoacyl-tRNA ligase/ histidine-tRNA ligase/ nucleotide binding	F:histidine-tRNA ligase activity, aminoacyl-tRNA ligase activity, nucleotide binding, ATP binding;P:histidyl-tRNA aminoacylation, translation, tRNA aminoacylation for protein translation;C:chloroplast, cytoplasm;OBMFAP	O.I.	C.G.	H.G.

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GSM ID	GSM311287
Assay name	Laser capture microdissected (LCM) embryo proper at the linear-cotyledon stage, biological replicate 1
GSE experiment	GSE12403: Expression data from Arabidopsis seed compartments at the linear-cotyledon stage

Microarray experiments to specifically-expressed genes

GSM ID GSM311287 Assay name Laser capture microdissected (LCM) embryo proper at the linear-cotyledon stage, biological replicate 1 GSE experiment GSE12403: Expression data from Arabidopsis seed compartments at the linear-cotyledon stage

GSM ID GSM311287

Assay name Laser capture microdissected (LCM) embryo proper at the linear-cotyledon stage, biological replicate 1

GSE experiment GSE12403: Expression data from Arabidopsis seed compartments at the linear-cotyledon stage