Metabolic pathway to genes

Genes assigned in the pathway

Query pathway ID 03410
Pathway name Base excision repair
Organism Arabidopsis_thaliana
Database KEGG PATHWAY

Click Gene ID to show a list of co-expressed genes.

Gene ID Repr. ID Gene name Functional description O.I. H.G. Other DB
At1g05900837100endonuclease-relatedF:sequence-specific DNA binding, DNA binding, catalytic activity, endonuclease activity;P:DNA repair, base-excision repair;C:intracellular;BOAMFPO.I.H.G.
At1g07370837249PCNA1 (PROLIFERATING CELLULAR NUCLEAR ANTIGEN)Encodes putative proliferating cell nuclear antigen involved in cell cycle regulation.O.I.H.G.
At1g07980837313NF-YC10 (NUCLEAR FACTOR Y, SUBUNIT C10)F:transcription factor activity;P:regulation of transcription;C:intracellular, chloroplast;MFPOO.I.H.G.
At1g08130837333ATLIG1 (ARABIDOPSIS THALIANA DNA LIGASE 1)Encodes the Arabidopsis DNA ligase 1 that provides the major DNA ligase activity in cells and plays a key role in both DNA replication and excision repair pathways. Indispensable for cell viability. AtLIG1 expresses one major and two minor mRNA transcripts differing only in the length of the 5' untranslated leader sequences preceding a common ORF. Translation from the first in-frame start codon produces an AtLIG1 isoform that is targeted exclusively to the mitochondria. Translation initiation from the second in-frame start codon produces an AtLIG1 isoform targeted only to the nucleus.O.I.H.G.
At1g08260837346TIL1 (TILTED 1)Similar to POL2A, DNA polymerase epsilon catalytic subunit. Essential for Arabidopsis growth. Null homozygotes are embryo lethal, partial loss of function alleles show embryo patterning defects such as root pole displacement. Delayed progression through cell cycle results in embryos with smaller numbers of larger cells.O.I.H.G.
At1g09815837513POLD4 (POLYMERASE DELTA 4)F:DNA-directed DNA polymerase activity;P:DNA replication;C:nucleus;FMPOO.I.H.G.
At1g10520837592DNA polymerase lambda (POLL)F:DNA binding, DNA-directed DNA polymerase activity, catalytic activity, nucleotidyltransferase activity;P:DNA repair, DNA replication;C:intracellular;MOBFAPVO.I.H.G.
At1g136352745751methyladenine glycosylase family proteinF:DNA-3-methyladenine glycosylase I activity, catalytic activity;P:DNA repair, base-excision repair;C:cellular_component unknown;BOPAMO.I.H.G.
At1g15970838167methyladenine glycosylase family proteinF:DNA-3-methyladenine glycosylase I activity, catalytic activity;P:DNA repair, base-excision repair;C:cellular_component unknown;BOPMAFO.I.H.G.
At1g19480838533HhH-GPD base excision DNA repair family proteinF:catalytic activity;P:DNA repair, base-excision repair;C:chloroplast;OBFPAO.I.H.G.
At1g21710838775OGG1 (8-OXOGUANINE-DNA GLYCOSYLASE 1)Encodes 8-oxoguanine-DNA glycosylase. DNA repair enzyme.O.I.H.G.
At1g49250841349ATP dependent DNA ligase family proteinF:DNA binding, DNA ligase (ATP) activity, ATP binding;P:DNA repair, DNA recombination, DNA replication;C:cellular_component unknown;BOMFAVPO.I.H.G.
At1g52500841681ATMMH-1 (ARABIDOPSIS THALIANA MUTM HOMOLOG-1)Encodes one of the splice variants of Arabidopsis thaliana MutM homolog. Has abasic lyase activity and does not exhibit significant cleavage of a double-stranded oligonucleotide that contained 8-oxo-guanine. Sequence similarity to atmmh-1.O.I.H.G.
At1g75090843846methyladenine glycosylase family proteinF:DNA-3-methyladenine glycosylase I activity, catalytic activity;P:DNA repair, base-excision repair;C:unknown;BOPAMFO.I.H.G.
At1g75230843860HhH-GPD base excision DNA repair family proteinF:catalytic activity;P:DNA repair, base-excision repair;C:nucleus;OBFPAMO.I.H.G.
At1g78650844201POLD3Similar to DNA polymerase delta (POLD3), which in other organism was shown to be involved in the elongation of DNA replication.O.I.H.G.
At1g80420844382DNA repair protein, putative (XRCC1)F:transcription coactivator activity;P:DNA repair;C:intracellular;MPOFO.I.H.G.
At2g27120817254TIL2 (TILTED 2)Encodes a protein with similarity to DNA polymerase epsilon catalytic subunit. Based on yeast two hybrid analysis, not predicted to be a subunit of the DNA polymerase epsilon complex. No phenotype observed in homozygous mutant embryos or plants but in combination with TIL1-1/til1-1 heterozygotes arrest earlier than til1 homozygotes suggesting TIL2 functions redundantly with TIL1.O.I.H.G.
At2g29570817506PCNA2 (PROLIFERATING CELL NUCLEAR ANTIGEN 2)Functionally interacts with POLH to repair DNA damaged by UVB damage.O.I.H.G.
At2g31320817690PARP2 (POLY(ADP-RIBOSE) POLYMERASE 2)Abiotic Stress-inducible gene.O.I.H.G.
At2g31450817703endonuclease-relatedF:4 iron, 4 sulfur cluster binding, sequence-specific DNA binding, DNA binding, catalytic activity, endonuclease activity;P:DNA repair, base-excision repair;C:intracellular;BOAMFPO.I.H.G.
At2g41460818744ARPapurinic endonuclease-redox protein. It functions as an apurinic/apyrimidinic class II endonuclease, and is involved in DNA repair.O.I.H.G.
At2g42120818812POLD2 (DNA POLYMERASE DELTA SMALL SUBUNIT)F:DNA binding, DNA-directed DNA polymerase activity;P:DNA replication;C:nucleus;OMFAPO.I.H.G.
At3g07930819984HhH-GPD base excision DNA repair family proteinF:unknown;P:base-excision repair;C:unknown;MPOO.I.H.G.
At3g12040820378DNA-3-methyladenine glycosylase (MAG)F:DNA binding, alkylbase DNA N-glycosylase activity, catalytic activity;P:base-excision repair;C:cellular_component unknown;BOMAPFO.I.H.G.
At3g12710820453methyladenine glycosylase family proteinF:DNA-3-methyladenine glycosylase I activity, catalytic activity;P:DNA repair, base-excision repair;C:unknown;BOPAMO.I.H.G.
At3g18630821394uracil DNA glycosylase family proteinF:uracil DNA N-glycosylase activity;P:DNA repair, base-excision repair;C:chloroplast;BOVMFPO.I.H.G.
At3g50880824252HhH-GPD base excision DNA repair family proteinF:catalytic activity;P:DNA repair, base-excision repair;C:chloroplast;OBFPAO.I.H.G.
At3g51880824351HMGB1 (HIGH MOBILITY GROUP B 1)Encodes a protein belonging to the subgroup of HMGB (high mobility group B) proteins that have a distinctive DNA-binding motif, the HMG-box domain. The motif confers non-sequence specific interaction with linear DNA and structure-specific binding to distorted DNA sites. The HMGB proteins are involved in the assembly of nucleoprotein complexes. Can be phosphorylated by CK2alpha. In interphase cells, HMGB1 is found throughout the nucleus, whereas in mitotic cells it is not chromatin-associated.O.I.H.G.
At4g02390828049APP (ARABIDOPSIS POLY(ADP-RIBOSE) POLYMERASE)Encodes a DNA dependent nuclear poly (ADP-ribose) polymerase (E.C.2.4.2.30), thought to be involved in post-translational modification .O.I.H.G.
At4g12740826886adenine-DNA glycosylase-related / MYH-relatedF:hydrolase activity, 4 iron, 4 sulfur cluster binding, catalytic activity, endonuclease activity;P:DNA repair, base-excision repair;C:unknown;MOBFPVAO.I.H.G.
At4g36050829761endonuclease/exonuclease/phosphatase family proteinF:zinc ion binding, nuclease activity;P:DNA repair;C:cellular_component unknown;OMFBPVO.I.H.G.
At5g13920831239zinc knuckle (CCHC-type) family proteinF:zinc ion binding, nucleic acid binding;P:biological_process unknown;C:cellular_component unknown;MPFOO.I.H.G.
At5g22110832272ATDPB2 (ARABIDOPSIS THALIANA DNA POLYMERASE EPSILON SUBUNIT B2)Encodes a protein with similarity to DNA polymerase epsilon subunit B an essential gene that is required for DNA replication. Homozygous mutants are embryo lethal. Expressed in meristematic , rapidly dividing regions.O.I.H.G.
At5g26680832721endonuclease, putativeF:5'-3' exonuclease activity, DNA binding, catalytic activity, nuclease activity;P:DNA repair;C:unknown;OMFBAPVO.I.H.G.
At5g44680834497methyladenine glycosylase family proteinF:DNA-3-methyladenine glycosylase I activity, catalytic activity;P:DNA repair, base-excision repair;C:unknown;BOPAMFO.I.H.G.
At5g57970835908methyladenine glycosylase family proteinF:DNA-3-methyladenine glycosylase I activity, catalytic activity;P:DNA repair, base-excision repair;C:unknown;BOMPAFO.I.H.G.
At5g63960836517EMB2780 (EMBRYO DEFECTIVE 2780)F:DNA-directed DNA polymerase activity, DNA binding, nucleotide binding, nucleic acid binding;P:nucleobase, nucleoside, nucleotide and nucleic acid metabolic process, DNA replication;C:nucleus;OVBMFAPO.I.H.G.

Comparison with co-expressed genes



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