Metabolic pathway to genes

Genes assigned in the pathway

Query pathway ID 01040
Pathway name Biosynthesis of unsaturated fatty acids
Organism Arabidopsis_thaliana
Database KEGG PATHWAY

Click Gene ID to show a list of co-expressed genes.

Gene ID Repr. ID Gene name Functional description O.I. H.G. Other DB
At1g01710839254acyl-CoA thioesterase family proteinF:cyclic nucleotide binding, acyl-CoA thioesterase activity;P:acyl-CoA metabolic process;C:peroxisome;BOMFPO.I.H.G.
At1g06290837140ACX3 (ACYL-COA OXIDASE 3)Encodes an acyl-CoA oxidase with specificity for medium chain fatty acids.O.I.H.G.
At1g06310837141ACX6 (ACYL-COA OXIDASE 6)Encodes a putative acyl-CoA oxidase. However, no transcripts have been detected for this gene and no altered phenotypes have been detected in plants mutant for this gene. This suggests that ACX6 does not significantly contribute to seedling beta-oxidation of fatty acids or indole-3-butyric acid in vivo.O.I.H.G.
At1g243608390533-oxoacyl-(acyl-carrier protein) reductase, chloroplast / 3-ketoacyl-acyl carrier protein reductaseF:3-oxoacyl-[acyl-carrier-protein] reductase activity;P:metabolic process, fatty acid biosynthetic process;C:chloroplast stroma, chloroplast, chloroplast envelope;BOMFPAVO.I.H.G.
At1g43800840977acyl-(acyl-carrier-protein) desaturase, putative / stearoyl-ACP desaturase, putativeF:acyl-[acyl-carrier-protein] desaturase activity, oxidoreductase activity, transition metal ion binding;P:fatty acid metabolic process, fatty acid biosynthetic process;C:membrane;PBOMO.I.H.G.
At1g63380842644binding / catalytic/ oxidoreductaseF:oxidoreductase activity, binding, catalytic activity;P:metabolic process, non-phosphorylated glucose catabolic process;C:cellular_component unknown;BOMFPAVO.I.H.G.
At2g29980817548FAD3 (FATTY ACID DESATURASE 3)Endoplasmic reticulum enzyme responsible for the synthesis of 18:3 fatty acids from phospholipids. Uses cytochrome b5 as electron donor.O.I.H.G.
At2g35690818138ACX5 (ACYL-COA OXIDASE 5)Encodes an acyl-CoA oxidase. Involved in jasmonate biosynthesis. Expressed uniformly in seedlings and throughout development.O.I.H.G.
At3g02610820709acyl-[acyl-carrier-protein] desaturase/ oxidoreductase/ transition metal ion bindingF:acyl-[acyl-carrier-protein] desaturase activity, oxidoreductase activity, transition metal ion binding;P:fatty acid metabolic process, fatty acid biosynthetic process;C:chloroplast;PBOMO.I.H.G.
At3g02620820737acyl-(acyl-carrier-protein) desaturase, putative / stearoyl-ACP desaturase, putativeF:acyl-[acyl-carrier-protein] desaturase activity, oxidoreductase activity, transition metal ion binding;P:fatty acid metabolic process, fatty acid biosynthetic process;C:unknown;PBOMO.I.H.G.
At3g02630820773acyl-(acyl-carrier-protein) desaturase, putative / stearoyl-ACP desaturase, putativeF:acyl-[acyl-carrier-protein] desaturase activity, oxidoreductase activity, transition metal ion binding;P:fatty acid metabolic process, fatty acid biosynthetic process;C:chloroplast, chloroplast stroma;PBOMO.I.H.G.
At3g03980819553short-chain dehydrogenase/reductase (SDR) family proteinF:oxidoreductase activity, binding, catalytic activity;P:metabolic process;C:unknown;BOMFPAVO.I.H.G.
At3g04000819555short-chain dehydrogenase/reductase (SDR) family proteinF:oxidoreductase activity, binding, catalytic activity;P:metabolic process;C:unknown;BOMFPAVO.I.H.G.
At3g11170820288FAD7 (FATTY ACID DESATURASE 7)Chloroplastic enzyme responsible for the synthesis of 16:3 and 18:3 fatty acids from galactolipids, sulpholipids and phosphatidylglycerol. Uses ferredoxin as electron donor. Gene expression is induced by wounding in shoot and root. The wound-response in shoot is independent of jasmonic acid mediated pathway whereas the root response is mediated by jasmonic acid.O.I.H.G.
At3g12120820387FAD2 (FATTY ACID DESATURASE 2)Major enzyme responsible for the synthesis of 18:2 fatty acids in the endoplasmic reticulum. Contains His-rich motifs, which contribute to the interaction with the electron donor cytochrome b5.O.I.H.G.
At3g51840824347ACX4 (ACYL-COA OXIDASE 4)Encodes a short-chain acyl-CoA oxidase, which catalyzes the first step of peroxisomal fatty acid beta-oxidation during early, post-germinative growth in oilseed species. Null mutants virtually lack short-chain acyl-CoA and are resistant to 2,4-dichlorophenoxybutyric acid, which is converted to the herbicide and auxin analogue 2,4-dichlorophenoxyacetic acid by beta-oxidation. Despite the almost complete loss of short-chain activity, lipid catabolism and seedling growth and establishment was unaltered in the acx4 mutant. However, double mutants in acx3acx4 (acx3 encodes medium chain acyl CoA oxidase) were not viable and arrested during embryogenesis.O.I.H.G.
At3g55360824702CER10Enoyl-CoA reductase is involved in all very long chain fatty acids (VLCFA) elongation reactions that are required for cuticular wax, storage lipid and sphingolipid metabolism. The protein is located in the ER, but in contrast to its yeast homolog TSC13 is not particularly enriched in the nuclear envelope-vacuole junction. Mutants in this gene show abnormal organ morphology and stem glossiness. Cells in all tissues are only about 1/3 of the size of wild type cells. The morphological changes are most likely to result from the reduction in the VLCFA content of sphingolipids. Mutants also show abnormalities in the endocytic membrane organization and transport.O.I.H.G.
At4g00520827955--O.I.H.G.
At4g13180826932short-chain dehydrogenase/reductase (SDR) family proteinF:oxidoreductase activity, binding, catalytic activity;P:response to arsenic;C:unknown;BOMFPAVO.I.H.G.
At4g16760827381ACX1 (ACYL-COA OXIDASE 1)Encodes a medium to long-chain acyl-CoA oxidase. Catalyzes the first step of fatty acid beta-oxidation. Involved in jasmonate biosynthesis. Gene expression is induced by wounding, drought stress, abscisic acid, and jasmonate.O.I.H.G.
At4g30950829220FAD6 (FATTY ACID DESATURASE 6)Chloroplastic enzyme responsible for the synthesis of 16:2 and 18:2 fatty acids from galactolipids, sulpholipids and phosphatidylglycerol. Uses ferredoxin as electron donor. Gene mutation resulted in reduced level of unsaturated fatty acids leading to susceptibility to photoinhibition.O.I.H.G.
At5g05580830441FAD8 (FATTY ACID DESATURASE 8)Encodes a temperature sensitive plastidic fatty acid desaturase.O.I.H.G.
At5g10480830912PAS2 (PASTICCINO 2)Protein tyrosine phosphatase-like involved in cell division and differentiation. Interacts with CDKA;1 only in its phosphorylated form, preventing dephosphorylation. Overexpression slowed down cell division in suspension cell cultures at the G2-to-M transition and early mitosis and inhibited Arabidopsis seedling growth. Localized in the cytoplasm of dividing cells but moved into the nucleus upon cell differentiation. Based on complementation of yeast mutant PAS2 has acyl-CoA dehydratase activity. It interacts with CER10, a component of the microsomal fatty acid elongase complex, suggesting a role in synthesis of VLCFAs (very long chain fatty acids).O.I.H.G.
At5g16230831483acyl-(acyl-carrier-protein) desaturase, putative / stearoyl-ACP desaturase, putativeF:acyl-[acyl-carrier-protein] desaturase activity, oxidoreductase activity, transition metal ion binding;P:fatty acid metabolic process, fatty acid biosynthetic process;C:chloroplast;PBOMO.I.H.G.
At5g16240831484acyl-(acyl-carrier-protein) desaturase, putative / stearoyl-ACP desaturase, putativeF:acyl-[acyl-carrier-protein] desaturase activity, oxidoreductase activity, transition metal ion binding;P:fatty acid metabolic process, fatty acid biosynthetic process;C:unknown;PBOMO.I.H.G.
At5g65110836635ACX2 (ACYL-COA OXIDASE 2)Encodes an acyl-CoA oxidase presumably involved in long chain fatty acid biosynthesis.O.I.H.G.

Comparison with co-expressed genes



Back to the CoP portal site

Back to the KAGIANA project homepage