Metabolic pathway to genes

Genes assigned in the pathway

Query pathway ID 00940
Pathway name Phenylpropanoid biosynthesis
Organism Arabidopsis_thaliana
Database KEGG PATHWAY

Click Gene ID to show a list of co-expressed genes.

Gene ID Repr. ID Gene name Functional description O.I. H.G. Other DB
At1g02640837940BXL2 (BETA-XYLOSIDASE 2)encodes a protein similar to a beta-xylosidase located in the extracellular matrix. This is a member of glycosyl hydrolase family 3 and has six other closely related members.O.I.H.G.
At1g05260837028RCI3 (RARE COLD INDUCIBLE GENE 3)Encodes a cold-inducible cationic peroxidase that is involved in the stress response. In response to low temperature, RCI3 transcripts accumulate in the aerial part and in roots of etiolated seedlings but only in roots of light-grown seedlings.O.I.H.G.
At1g14540838016anionic peroxidase, putativeF:electron carrier activity, peroxidase activity, heme binding;P:response to oxidative stress;C:endomembrane system;PFOBMO.I.H.G.
At1g14550838017anionic peroxidase, putativeF:electron carrier activity, peroxidase activity, heme binding;P:response to oxidative stress;C:endomembrane system;PFOBMO.I.H.G.
At1g15950838165CCR1 (CINNAMOYL COA REDUCTASE 1)Encodes a cinnamoyl CoA reductase. Involved in lignin biosynthesis.O.I.H.G.
At1g204808386364-coumarate--CoA ligase family protein / 4-coumaroyl-CoA synthase family proteinF:4-coumarate-CoA ligase activity;P:phenylpropanoid metabolic process, metabolic process;C:cellular_component unknown;BOFMPAVO.I.H.G.
At1g24110839023peroxidase, putativeF:electron carrier activity, peroxidase activity, heme binding;P:response to oxidative stress;C:endomembrane system;PFOBMO.I.H.G.
At1g24735839082O-methyltransferaseF:O-methyltransferase activity;P:unknown;C:cytosol;BOPMFAO.I.H.G.
At1g26560839196BGLU40 (BETA GLUCOSIDASE 40)F:cation binding, hydrolase activity, hydrolyzing O-glycosyl compounds, catalytic activity;P:carbohydrate metabolic process;C:apoplast, chloroplast;BOPMFAO.I.H.G.
At1g30870839971cationic peroxidase, putativeF:electron carrier activity, peroxidase activity, heme binding;P:response to oxidative stress;C:endomembrane system;PFOMO.I.H.G.
At1g34510840353peroxidase, putativeF:electron carrier activity, peroxidase activity, heme binding;P:response to oxidative stress;C:endomembrane system;PFOO.I.H.G.
At1g44970841062peroxidase, putativeF:electron carrier activity, peroxidase activity, heme binding;P:response to oxidative stress;C:endomembrane system;PFOBMO.I.H.G.
At1g49570841381peroxidase, putativeF:electron carrier activity, peroxidase activity, heme binding;P:response to oxidative stress;C:endomembrane system;PFOBO.I.H.G.
At1g516808415934CL1 (4-COUMARATE:COA LIGASE 1)encodes an isoform of 4-coumarate:CoA ligase (4CL), which is involved in the last step of the general phenylpropanoid pathway. In addition to 4-coumarate, it also converts ferulate. The catalytic efficiency was in the following (descending) order: p-coumaric acid, ferulic acid, caffeic acid and 5-OH-ferulic acid. At4CL1 was unable to use sinapic acid as substrate.O.I.H.G.
At1g62940842596ACOS5 (ACYL-COA SYNTHETASE 5)encodes an acyl-CoA synthetase, has in vitro activity towards medium- to long-chain fatty acids and their hydroxylated derivatives. Expressed in the tapetum. Involved in pollen wall exine formation. Null mutants were devoid of pollen grains at anther maturity and were completely male sterile.O.I.H.G.
At1g650608428144CL3encodes an isoform of 4-coumarate:CoA ligase (4CL), which is involved in the last step of the general phenylpropanoid pathway. mRNA levels are not induced in response to wounding or to fungal infection by P. parasitica. mRNA is expressed in flowers, to a lesser degree in mature leaves and siliques and marginally in seedling roots and bolting stems of mature plants. The catalytic efficiency was in the following (descending) order: p-coumaric acid, caffeic acid, ferulic acid, cinnamic acid and 5-OH-ferulic acid. At4CL3 was unable to use sinapic acid as substrate.O.I.H.G.
At1g68850843218peroxidase, putativeF:electron carrier activity, peroxidase activity, heme binding;P:response to oxidative stress;C:endomembrane system;PFOBMO.I.H.G.
At1g71695843498peroxidase 12 (PER12) (P12) (PRXR6)F:electron carrier activity, peroxidase activity, heme binding;P:response to oxidative stress;C:cell wall, vacuole, membrane, plant-type cell wall;PFOBO.I.H.G.
At1g74540843795CYP98A8member of CYP98AO.I.H.G.
At1g74550843796CYP98A9member of CYP98AO.I.H.G.
At1g80820844421CCR2 (CINNAMOYL COA REDUCTASE)Encodes an cinnamoyl CoA reductase isoform. Involved in lignin biosynthesis.O.I.H.G.
At2g18140816327peroxidase, putativeF:electron carrier activity, peroxidase activity, heme binding;P:response to oxidative stress;C:cell wall;PFOBMO.I.H.G.
At2g18150816328peroxidase, putativeF:electron carrier activity, peroxidase activity, heme binding;P:response to oxidative stress, response to nematode;C:cell wall;PFOBMO.I.H.G.
At2g18980816415peroxidase, putativeF:electron carrier activity, peroxidase activity, heme binding;P:response to oxidative stress;C:endomembrane system;PFOBMO.I.H.G.
At2g22420816773peroxidase 17 (PER17) (P17)F:electron carrier activity, peroxidase activity, heme binding;P:response to oxidative stress;C:endomembrane system;PFOBO.I.H.G.
At2g22990816830SNG1 (SINAPOYLGLUCOSE 1)sinapoylglucose:malate sinapoyltransferase. Catalyzes the formation of sinapoylmalate from sinapoylglucose. Mutants accumulate excess sinapoylglucose.O.I.H.G.
At2g24800817017peroxidase, putativeF:electron carrier activity, peroxidase activity, heme binding;P:response to oxidative stress;C:endomembrane system;PFOBMO.I.H.G.
At2g30490817599C4H (CINNAMATE-4-HYDROXYLASE)Encodes a cinnamate-4-hydroxylase.O.I.H.G.
At2g34060817967peroxidase, putativeF:electron carrier activity, peroxidase activity, heme binding;P:response to oxidative stress;C:endomembrane system;PFOMO.I.H.G.
At2g37040818280pal1 (Phe ammonia lyase 1)encodes a protein similar to phenylalanine ammonia-lyaseO.I.H.G.
At2g37130818289peroxidase 21 (PER21) (P21) (PRXR5)F:electron carrier activity, peroxidase activity, heme binding;P:defense response to fungus;C:endomembrane system;PFOO.I.H.G.
At2g38380818419peroxidase 22 (PER22) (P22) (PRXEA) / basic peroxidase EF:electron carrier activity, peroxidase activity, heme binding;P:response to salt stress;C:plant-type cell wall;PFOO.I.H.G.
At2g38390818420peroxidase, putativeF:electron carrier activity, peroxidase activity, heme binding;P:response to salt stress;C:endomembrane system;PFOO.I.H.G.
At2g39040818490peroxidase, putativeF:electron carrier activity, peroxidase activity, heme binding;P:response to oxidative stress;C:endomembrane system;PFOO.I.H.G.
At2g40890818686CYP98A3 (cytochrome P450, family 98, subfamily A, polypeptide 3)encodes coumarate 3-hydroxylase (C3H), a P450-dependent monooxygenase. Involved in lignin biosynthesis and flavonoid biosynthesis. Also affects the biosynthesis of coumarins such as scopoletin and scopolin as a branching-out-pathway from the phenylpropanoid acid level.O.I.H.G.
At2g41480818746electron carrier/ heme binding / peroxidaseF:electron carrier activity, peroxidase activity, heme binding;P:response to oxidative stress;C:unknown;POFBMO.I.H.G.
At2g43480818949peroxidase, putativeF:electron carrier activity, peroxidase activity, heme binding;P:response to oxidative stress;C:endomembrane system;PFOMO.I.H.G.
At2g44450819052BGLU15 (BETA GLUCOSIDASE 15)F:cation binding, hydrolase activity, hydrolyzing O-glycosyl compounds, catalytic activity;P:carbohydrate metabolic process;C:cell wall, plant-type cell wall;BOPMFAO.I.H.G.
At2g44480819055BGLU17 (BETA GLUCOSIDASE 17)F:cation binding, hydrolase activity, hydrolyzing O-glycosyl compounds, catalytic activity;P:carbohydrate metabolic process;C:endomembrane system;BOPMFAO.I.H.G.
At3g01190821314peroxidase 27 (PER27) (P27) (PRXR7)F:electron carrier activity, peroxidase activity, heme binding;P:response to oxidative stress;C:endomembrane system;PFOBMO.I.H.G.
At3g03670821193peroxidase, putativeF:electron carrier activity, peroxidase activity, heme binding;P:response to oxidative stress;C:plant-type cell wall;PFOBO.I.H.G.
At3g10340820196PAL4 (Phenylalanine ammonia-lyase 4)F:ammonia-lyase activity, ammonia ligase activity, catalytic activity;P:L-phenylalanine catabolic process, biosynthetic process;C:cytoplasm;BPOFMAO.I.H.G.
At3g17070820964peroxidase, putativeF:electron carrier activity, peroxidase activity, heme binding;P:response to oxidative stress;C:endomembrane system;PFOBMO.I.H.G.
At3g18080821333BGLU44 (B-S GLUCOSIDASE 44)F:in 6 functions;P:carbohydrate metabolic process;C:cytosolic ribosome, cell wall, plant-type cell wall;BOPMFAO.I.H.G.
At3g19450821479ATCAD4Encodes a catalytically active cinnamyl alcohol dehydrogenase which uses p-coumaryl aldehyde as a preferred substrate. It can also use caffeyl, coniferyl and d-hydroxyconiferyl aldehydes as substrates.O.I.H.G.
At3g212308216774CL5 (4-coumarate:CoA ligase 5)The gene encodes a 4-coumarate coenzyme A ligase being able to use sinapate as substrate. The catalytic efficiency was in the following (descending) order: p-coumaric acid, caffeic acid, 5-OH-ferulic acid, ferulic acid and sinapic acid. At4CL5 was unable to use cinnamic acid as substrate. Knockout of At4CL5 (4cl5) revealed no effect on syringyl lignin content indicating that the activity observed does probably not occur in vivo.O.I.H.G.
At3g212408216784CL2 (4-COUMARATE:COA LIGASE 2)encodes an isoform of 4-coumarate:CoA ligase (4CL), which is involved in the last step of the general phenylpropanoid pathway. The catalytic efficiency was in the following (descending) order: p-coumaric acid, caffeic acid, ferulic acid, 5-OH-ferulic acid and cinnamic acid. At4CL2 was unable to use sinapic acid as substrate.O.I.H.G.
At3g21770821731peroxidase 30 (PER30) (P30) (PRXR9)F:transferase activity, transferring glycosyl groups, peroxidase activity;P:response to oxidative stress;C:cell wall, nucleus, cytoplasm, plant-type cell wall;PFOBMO.I.H.G.
At3g24503822042ALDH2C4Arabidopsis thaliana aldehyde dehydrogenase AtALDH1a mRNA. a sinapaldehyde dehydrogenase catalyzes both the oxidation of coniferylaldehyde and sinapaldehyde forming ferulic acid and sinapic acid, respectivelyO.I.H.G.
At3g28200822446peroxidase, putativeF:electron carrier activity, peroxidase activity, heme binding;P:response to oxidative stress;C:plant-type cell wall;PFOBO.I.H.G.
At3g47000823853glycosyl hydrolase family 3 proteinF:hydrolase activity, hydrolyzing O-glycosyl compounds;P:carbohydrate metabolic process;C:cellular_component unknown;BOFPAMO.I.H.G.
At3g47050823858glycosyl hydrolase family 3 proteinF:hydrolase activity, hydrolyzing O-glycosyl compounds;P:carbohydrate metabolic process;C:vacuole;BOFPAMO.I.H.G.
At3g49110824072PRXCA (PEROXIDASE CA)Class III peroxidase Perx33. Expressed in roots. Located in the cell wall. Involved in cell elongation. Expression activated by light. May play a role in generating H2O2 during defense response.O.I.H.G.
At3g49120824073PRXCB (PEROXIDASE CB)Class III peroxidase Perx34. Expressed in roots, leaves and stems. Located in the cell wall. Involved in cell elongation. Expression activated by light. May play a role in generating H2O2 during defense response.O.I.H.G.
At3g49960824158peroxidase, putativeF:electron carrier activity, peroxidase activity, heme binding;P:response to oxidative stress;C:endomembrane system;PFOO.I.H.G.
At3g50740824238UGT72E1 (UDP-glucosyl transferase 72E1)UGT72E1 is an UDPG:coniferyl alcohol glucosyltransferase which specifically glucosylates sinapyl- and coniferyl aldehydes. The enzyme is thought to be involved in lignin metabolism.O.I.H.G.
At3g53260824493PAL2Encodes phenylalanine lyase.O.I.H.G.
At4g051608258644-coumarate--CoA ligase, putative / 4-coumaroyl-CoA synthase, putativeEncodes a peroxisomal protein involved in the activation of fatty acids through esterification with CoA. At4g05160 preferentially activates fatty acids with medium chain length (C6:0 and C7:0) as well as even-numbered long-chain fatty acids (C14:0, C16:0 and C18:0). At4g05160 was also able to catalyze the conversion of OPC-6:0 to its CoA ester and is therefore thought to be involved in the peroxisomal β-oxidation steps of jasmonic acid biosynthesis.O.I.H.G.
At4g08770826447peroxidase, putativeF:electron carrier activity, peroxidase activity, heme binding;P:response to oxidative stress;C:vacuole;POFO.I.H.G.
At4g08780826448peroxidase, putativeF:electron carrier activity, peroxidase activity, heme binding;P:response to oxidative stress;C:vacuole;POFMO.I.H.G.
At4g11290826731peroxidase, putativeF:electron carrier activity, peroxidase activity, heme binding;P:response to oxidative stress;C:endomembrane system;PFOBO.I.H.G.
At4g16270827322peroxidase 40 (PER40) (P40)F:electron carrier activity, peroxidase activity, heme binding;P:response to oxidative stress;C:endomembrane system;PFOBMO.I.H.G.
At4g17690827489peroxidase, putativeF:electron carrier activity, peroxidase activity, heme binding;P:response to oxidative stress;C:endomembrane system;PFOBMO.I.H.G.
At4g21960828285PRXR1Encodes AT4g21960 (AT4g21960/T8O5_170).O.I.H.G.
At4g26010828707peroxidase, putativeF:electron carrier activity, peroxidase activity, heme binding;P:response to oxidative stress;C:endomembrane system;PFOO.I.H.G.
At4g30170829140peroxidase, putativeF:electron carrier activity, peroxidase activity, heme binding;P:response to oxidative stress;C:endomembrane system;PFOBO.I.H.G.
At4g31760829304peroxidase, putativeF:electron carrier activity, peroxidase activity, heme binding;P:response to oxidative stress;C:endomembrane system;PFOBMO.I.H.G.
At4g33420829479peroxidase, putativeF:electron carrier activity, peroxidase activity, heme binding;P:response to oxidative stress;C:unknown;PFOBMO.I.H.G.
At4g34050829551caffeoyl-CoA 3-O-methyltransferase, putativeF:caffeoyl-CoA O-methyltransferase activity;P:coumarin biosynthetic process, response to cadmium ion;C:cytosol;BOPMFAO.I.H.G.
At4g34230829572ATCAD5 (CINNAMYL ALCOHOL DEHYDROGENASE 5)Encodes a catalytically active cinnamyl alcohol dehydrogenase which uses p-coumaryl aldehyde as a preferred substrate. It can also use sinapyl, caffeyl, coniferyl and d-hydroxyconiferyl aldehydes as substrates.O.I.H.G.
At4g36220829779FAH1 (FERULIC ACID 5-HYDROXYLASE 1)encodes ferulate 5-hydroxylase (F5H). Involved in lignin biosynthesis.O.I.H.G.
At4g36430829795peroxidase, putativeF:electron carrier activity, peroxidase activity, heme binding;P:response to other organism;C:cell wall;PFOBMO.I.H.G.
At4g37520829907peroxidase 50 (PER50) (P50) (PRXR2)F:electron carrier activity, peroxidase activity, heme binding;P:response to oxidative stress;C:cytoplasm;PFOMO.I.H.G.
At4g37530829908peroxidase, putativeF:electron carrier activity, peroxidase activity, heme binding;P:response to salt stress;C:endomembrane system;PFOO.I.H.G.
At5g04230830302PAL3 (PHENYL ALANINE AMMONIA-LYASE 3)Member of Phenylalanine ammonialyase (PAL) gene family.Differs significantly from PAL1 and PAL2 and other sequenced plant PAL genesO.I.H.G.
At5g04330830312cytochrome P450, putative / ferulate-5-hydroxylase, putativeF:electron carrier activity, monooxygenase activity, iron ion binding, oxygen binding, heme binding;P:unknown;C:endomembrane system;MPFBOAVO.I.H.G.
At5g05340830416peroxidase, putativeF:electron carrier activity, peroxidase activity, heme binding;P:response to oxidative stress;C:apoplast, cell wall;PFOBMO.I.H.G.
At5g06720830561peroxidase, putativeF:electron carrier activity, peroxidase activity, heme binding;P:response to oxidative stress;C:endomembrane system;PFOMVO.I.H.G.
At5g06730830562peroxidase, putativeF:electron carrier activity, peroxidase activity, heme binding;P:response to oxidative stress;C:plasma membrane;PFOBMO.I.H.G.
At5g09640830823SCPL19encodes a serine carboxypeptidase-like (SCPL) protein. Mutants accumulate sinapoylglucose instead of sinapoylcholine, and have increased levels of choline and decreased activity of the enzyme sinapoylglucose:choline sinapoyltransferase.O.I.H.G.
At5g14130831263peroxidase, putativeF:electron carrier activity, peroxidase activity, heme binding;P:response to oxidative stress;C:endomembrane system;PFOBO.I.H.G.
At5g15180831370peroxidase, putativeF:electron carrier activity, peroxidase activity, heme binding;P:response to oxidative stress;C:endomembrane system;PFOBO.I.H.G.
At5g17820831650peroxidase 57 (PER57) (P57) (PRXR10)F:electron carrier activity, peroxidase activity, heme binding;P:response to oxidative stress;C:cell wall, membrane, plant-type cell wall;PFOMO.I.H.G.
At5g19880832110peroxidase, putativeF:electron carrier activity, peroxidase activity, heme binding;P:response to ethylene stimulus, response to oxidative stress, response to virus, N-terminal protein myristoylation;C:endomembrane system;PFOMO.I.H.G.
At5g19890832111peroxidase, putativeF:electron carrier activity, peroxidase activity, heme binding;P:response to oxidative stress;C:nucleus, cytoplasm;PFOBO.I.H.G.
At5g22410832302peroxidase, putativeF:electron carrier activity, peroxidase activity, heme binding;P:response to oxidative stress;C:endomembrane system;PFOO.I.H.G.
At5g24070832472peroxidase family proteinF:electron carrier activity, peroxidase activity, heme binding;P:response to oxidative stress;C:endomembrane system;PFOMO.I.H.G.
At5g26310832700UGT72E3UGT72E3 is an UDPG:coniferyl alcohol glucosyltransferase which glucosylates sinapyl- and coniferyl alcohol as well as sinapic acid. The enzyme is thought to be involved in lignin- and phenylpropanoid metabolism. A knockdown mutant line (72E3KD) was obtained using RNAi silencing. No reduction in coniferyl alcohol 4-O-glucoside and sinapyl alcohol 4-O-glucoside was detected in this line compared to wildtype, in contrast with the knockdown line constructed for UGT72E2 displayed a twofold reduction in the these phenylpropanoid 4-O-glucosides.O.I.H.G.
At5g40150834012peroxidase, putativeF:electron carrier activity, peroxidase activity, heme binding;P:response to oxidative stress;C:endomembrane system;PFOBO.I.H.G.
At5g42180834223peroxidase 64 (PER64) (P64) (PRXR4)F:electron carrier activity, peroxidase activity, heme binding;P:response to oxidative stress;C:plant-type cell wall;PFOBMO.I.H.G.
At5g42260834231BGLU12 (BETA GLUCOSIDASE 12)F:cation binding, hydrolase activity, hydrolyzing O-glycosyl compounds, catalytic activity;P:carbohydrate metabolic process;C:endomembrane system;BOPMFAO.I.H.G.
At5g44640834493BGLU13 (BETA GLUCOSIDASE 13)F:cation binding, hydrolase activity, hydrolyzing O-glycosyl compounds, catalytic activity;P:carbohydrate metabolic process;C:endomembrane system;BOPMFAO.I.H.G.
At5g47000834746peroxidase, putativeF:xylan 1,4-beta-xylosidase activity, peroxidase activity;P:response to oxidative stress;C:endomembrane system;PFOBMO.I.H.G.
At5g51890835264peroxidaseencodes peroxidase involved in the lignification of tracheary elements (TE) in rootsO.I.H.G.
At5g58390835952peroxidase, putativeF:electron carrier activity, peroxidase activity, heme binding;P:response to oxidative stress;C:endomembrane system;PFOBMO.I.H.G.
At5g58400835953peroxidase, putativeF:electron carrier activity, peroxidase activity, heme binding;P:response to oxidative stress;C:endomembrane system;PFOBMO.I.H.G.
At5g64100836531peroxidase, putativeF:electron carrier activity, peroxidase activity, heme binding;P:response to oxidative stress;C:cell wall;PFOO.I.H.G.
At5g64110836532peroxidase, putativeF:electron carrier activity, peroxidase activity, heme binding;P:response to oxidative stress;C:membrane;PFOBO.I.H.G.
At5g64120836533peroxidase, putativeencodes a cell wall bound peroxidase that is induced by hypo-osmolarityO.I.H.G.
At5g66390836771peroxidase 72 (PER72) (P72) (PRXR8)F:electron carrier activity, peroxidase activity, heme binding;P:response to oxidative stress;C:endomembrane system;PFOBO.I.H.G.
At5g66690836802UGT72E2UGT72E2 is an UDPG:coniferyl alcohol glucosyltransferase which glucosylates sinapyl- and coniferyl aldehydes as well as sinapyl- and coniferyl alcohol. The enzyme is thought to be involved in lignin metabolism. A knockdown mutant line (72E2KD) was obtained using RNAi silencing. A twofold reduction in coniferyl alcohol 4-O-glucoside and sinapyl alcohol 4-O-glucoside was detected in this line compared to wildtype. In comparison, both knockout and knockdown lines of UGT72E1 and UGT72E3, respectively, failed to display the same reduction in phenylpropanoid 4-O-glucosides.O.I.H.G.
At5g67400836876peroxidase 73 (PER73) (P73) (PRXR11)F:electron carrier activity, peroxidase activity, heme binding;P:response to oxidative stress;C:endomembrane system;PFOO.I.H.G.

Comparison with co-expressed genes



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