Metabolic pathway to genes

Genes assigned in the pathway

Query pathway ID 00770
Pathway name Pantothenate and CoA biosynthesis
Organism Arabidopsis_thaliana
Database KEGG PATHWAY

Click Gene ID to show a list of co-expressed genes.

Gene ID Repr. ID Gene name Functional description O.I. H.G. Other DB
At1g10070837543ATBCAT-2 (ARABIDOPSIS THALIANA BRANCHED-CHAIN AMINO ACID TRANSAMINASE 2)Encodes a chloroplast branched-chain amino acid aminotransferase. Complements the yeast leu/iso-leu/val auxotrophy mutant.O.I.H.G.
At1g50090841432aminotransferase class IV family proteinF:branched-chain-amino-acid transaminase activity, catalytic activity;P:branched chain family amino acid metabolic process, metabolic process;C:cellular_component unknown;BOFMPAO.I.H.G.
At1g50110841433branched-chain amino acid aminotransferase 6 / branched-chain amino acid transaminase 6 (BCAT6)F:branched-chain-amino-acid transaminase activity, catalytic activity;P:branched chain family amino acid metabolic process, metabolic process;C:cellular_component unknown;BOFMPAO.I.H.G.
At2g27490817294ATCOAEAT2G27490 encodes dephospho-CoA kinase. The molecular function was shown to phosphorylate the ribosyl moiety forming CoA.O.I.H.G.
At3g18030821327ATHAL3Aflavin mononucleotide flavoprotein involved in salt and osmotic tolerance HAL3A encodes for phosphopantothenoylcysteine decarboxylase being involved in Coenzyme A biosynthesis. HAL3A is predominant over another gene with the presumably same function (HAL3B).O.I.H.G.
At3g19710821508BCAT4 (BRANCHED-CHAIN AMINOTRANSFERASE4)Belongs to the branched-chain amino acid aminotransferase gene family. Encodes a methionine-oxo-acid transaminase. Involved in the methionine chain elongation pathway that leads to the ultimate biosynthesis of methionine-derived glucosinolates.O.I.H.G.
At3g23940821977dehydratase familyF:catalytic activity, dihydroxy-acid dehydratase activity;P:branched chain family amino acid biosynthetic process, isoleucine biosynthetic process, metabolic process, valine biosynthetic process;C:chloroplast stroma, chloroplast;OBFAPMO.I.H.G.
At3g48560824015CSR1 (CHLORSULFURON/IMIDAZOLINONE RESISTANT 1)Catalyzes the formation of acetolactate from pyruvate, the first step in valine and isoleucine biosynthesis. Requires FAD, thiamine pyrophosphate and Mg. Inhibited by the sulphonylurea herbicide, chlorsulphuron, and the imidazolinone herbicide, imazapyr. The obtained crystal structure of acetohydroxyacid synthase AHAS, EC 2.2.1.6)in complex with herbicides of the sulphonylurea and imidazolinone family reveals the molecular basis for substrate/inhibitor binding.O.I.H.G.
At3g49680824130BCAT3 (BRANCHED-CHAIN AMINOTRANSFERASE 3)Encodes a chloroplast branched-chain amino acid aminotransferase. Complements the yeast leu/iso-leu/val auxotrophy mutant.O.I.H.G.
At3g58610825030ketol-acid reductoisomeraseF:coenzyme binding, oxidoreductase activity, binding, ketol-acid reductoisomerase activity, catalytic activity;P:response to cadmium ion, branched chain family amino acid biosynthetic process;C:in 6 components;BOFAPO.I.H.G.
At5g12200831093dihydropyrimidinase / DHPase / dihydropyrimidine amidohydrolase / hydantoinase (PYD2)F:hydrolase activity, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, dihydropyrimidinase activity;P:unknown;C:endomembrane system;OBMAFPO.I.H.G.
At5g48840834942PANC (ARABIDOPSIS HOMOLOG OF BACTERIAL PANC)Encodes a pantothenate synthetase that appears to be located in the cytosol. This protein is expected to play a role in pantothenate (vitamin B5) biosynthesis. Analysis of the catalytic properties of this enzyme indicate that it might be able to synthesize adequate amounts of pantothenate even in the presence of low levels of pantoate.O.I.H.G.
At5g57850835895aminotransferase class IV family proteinF:4-amino-4-deoxychorismate lyase activity, catalytic activity;P:tetrahydrofolate biosynthetic process;C:chloroplast;BOAPFO.I.H.G.
At5g64370836558BETA-UP (beta-ureidopropionase)PYD3 encodes a beta-ureidopropionase which, when expressed in E. coli, has been shown to convert beta-ureidopropionate into beta-alanine.O.I.H.G.
At5g65780836707ATBCAT-5encodes a chloroplast branched-chain amino acid aminotransferase, can complement the yeast leu/iso-leu/val auxotrophy mutantO.I.H.G.

Genes co-expressed with At2g27490

At2g27490NF: 0.25%ile: 27.9SF: 0.10SP: 0.07SR: 0.20

Gene IDRepr. IDGene NameFunctional Description
At2g27490817294ATCOAEAT2G27490 encodes dephospho-CoA kinase. The molecular function was shown to phosphorylate the ribosyl moiety forming CoA.
At5g04410830320NAC2NAC family member, hypothetical transcriptional regulator
At3g48070823962protein binding / zinc ion bindingF:protein binding, zinc ion binding;P:unknown;C:chloroplast;MFPOB
At4g27680828882MSP1 protein, putative / intramitochondrial sorting protein, putativeF:nucleoside-triphosphatase activity, ATPase activity, nucleotide binding, ATP binding;P:unknown;C:endomembrane system;OBMFPAV
At5g58020835914unknown proteinF:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;MFOP



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