Metabolic pathway to genes

Genes assigned in the pathway

Query pathway ID 00380
Pathway name Tryptophan metabolism
Organism Arabidopsis_thaliana
Database KEGG PATHWAY

Click Gene ID to show a list of co-expressed genes.

Gene ID Repr. ID Gene name Functional description O.I. H.G. Other DB
At1g04610839474flavin-containing monooxygenase / FMO (YUCCA3)F:oxidoreductase activity;P:auxin biosynthetic process;C:unknown;BOFMPAO.I.H.G.
At1g20620838651CAT3 (CATALASE 3)Catalase, catalyzes the breakdown of hydrogen peroxide (H2O2) into water and oxygen.O.I.H.G.
At1g20630838652CAT1 (CATALASE 1)Catalyzes the reduction of hydrogen peroxide using heme group as cofactor. Protects cells from toxicity by H2O2.O.I.H.G.
At1g23800838991ALDH2B7Encodes a mitochondrial aldehyde dehydrogenase; nuclear gene for mitochondrial product.O.I.H.G.
At1g24100839022UGT74B1 (UDP-glucosyl transferase 74B1)Encodes a UDP-glucose:thiohydroximate S-glucosyltransferase, involved in glucosinolate biosynthesisO.I.H.G.
At1g54100841849ALDH7B4 (Aldehyde Dehydrogenase 7B4)Aldehyde dehydrogenaseO.I.H.G.
At1g74100843750SOT16 (SULFOTRANSFERASE 16)encodes a desulfoglucosinolate sulfotransferase, involved in the final step of glucosinolate core structure biosynthesis. Has a broad-substrate specificity with different desulfoglucosinolates, the best substrate is indole-3-methyl-dsGS, followed by benzyl-dsGS. Expression was induced by wounding, jasmonate and ethylene stimulates.O.I.H.G.
At2g20340816553tyrosine decarboxylase, putativeF:pyridoxal phosphate binding, carboxy-lyase activity, catalytic activity, tyrosine decarboxylase activity;P:amino acid metabolic process, response to wounding;C:cellular_component unknown;MBOFPAVO.I.H.G.
At2g20610816585SUR1 (SUPERROOT 1)Confers auxin overproduction. Mutants have an over-proliferation of lateral roots. Encodes a C-S lyase involved in converting S-alkylthiohydroximate to thiohydroximate in glucosinolate biosynthesis.O.I.H.G.
At2g22330816765CYP79B3Encodes a cytochrome P450. Involved in tryptophan metabolism. Converts Trp to indole-3-acetaldoxime (IAOx), a precursor to IAA and indole glucosinolates.O.I.H.G.
At2g25840817126OVA4 (ovule abortion 4)F:nucleotide binding, aminoacyl-tRNA ligase activity, tryptophan-tRNA ligase activity, ATP binding;P:N-terminal protein myristoylation, ovule development, tRNA aminoacylation for protein translation;C:mitochondrion, chloroplast;OBMFAPO.I.H.G.
At2g30770817628CYP71A13 (cytochrome P450, family 71, subfamily A, polypeptide 13)putative cytochrome P450O.I.H.G.
At2g44460819053BGLU28 (BETA GLUCOSIDASE 28)F:cation binding, hydrolase activity, hydrolyzing O-glycosyl compounds, catalytic activity;P:carbohydrate metabolic process;C:membrane;BOPMFAO.I.H.G.
At2g44470819054BGLU29 (BETA GLUCOSIDASE 29)F:cation binding, hydrolase activity, hydrolyzing O-glycosyl compounds, catalytic activity;P:carbohydrate metabolic process;C:endomembrane system;BPOMFAO.I.H.G.
At2g44490819056PEN2 (PENETRATION 2)Encodes a glycosyl hydrolase that localizes to peroxisomes and acts as a component of an inducible preinvasion resistance mechanism. Required for mlo resistance.O.I.H.G.
At3g04600819617tRNA synthetase class I (W and Y) family proteinF:tryptophan-tRNA ligase activity, nucleotide binding, aminoacyl-tRNA ligase activity, ATP binding;P:tryptophanyl-tRNA aminoacylation, tRNA aminoacylation for protein translation;C:cytosol;BOAMFPVO.I.H.G.
At3g44300823555NIT2 (nitrilase 2)Encodes an enzyme that catalyzes the hydrolysis of indole-3-acetonitrile (IAN) to indole-3-acetic acid (IAA) (nitrile aminohydrolase, EC 3.5.5.1) and IAN to indole-3-acetamide (IAM) at lower levels. Mutants have reduced sensitivity to IAN and are sensitive to IAA. This enzyme likely participates in other non-auxin-related metabolic pathways.O.I.H.G.
At3g44310823556NIT1Mutants are resistant to indole-3-acetonitrile (IAN). NIT1 catalyzes the terminal activation step in indole-acetic acid biosynthesis. Predominantly expressed isoform of nitrilase isoenzyme family. Aggregation of NIT1 in cells directly abutting wound sites is one of the earliest events associated with wound and herbicide-induced cell death. The protein undergoes thiolation following treatment with the oxidant tert-butylhydroperoxide. It is also involved in the conversion of IAN to IAM (indole-3-acetamide) and other non-auxin-related metabolic processes.O.I.H.G.
At3g44320823557NIT3 (NITRILASE 3)This enzyme catalyzes the hydrolysis of indole-3-acetonitrile (IAN) to indole-3-acetic acid (IAA) (EC 3.5.5.1) and IAN to indole-3-acetamide (IAM) at lower levels. It is the only one of the four Arabidopsis nitrilases whose mRNA levels are strongly induced when plants experience sulphur deprivation. This enzyme likely participates in other non-auxin-related metabolic pathways.O.I.H.G.
At3g48000823955ALDH2B4 (ALDEHYDE DEHYDROGENASE 2B4)Encodes a putative (NAD+) aldehyde dehydrogenase.O.I.H.G.
At3g554108247072-oxoglutarate dehydrogenase E1 component, putative / oxoglutarate decarboxylase, putative / alpha-ketoglutaric dehydrogenase, putativeF:oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor, oxoglutarate dehydrogenase (succinyl-transferring) activity, thiamin pyrophosphate binding;P:glycolysis, metabolic process;C:mitochondrion;OBMFPAO.I.H.G.
At4g13260826956YUC2 (YUCCA2)F:NADP or NADPH binding, oxidoreductase activity, FAD binding, flavin-containing monooxygenase activity;P:auxin biosynthetic process;C:unknown;BOFMPAO.I.H.G.
At4g16210827314ECHIA (ENOYL-COA HYDRATASE/ISOMERASE A)F:catalytic activity;P:metabolic process;C:peroxisome;BOMFPAO.I.H.G.
At4g16800827386enoyl-CoA hydratase, putativeF:enoyl-CoA hydratase activity, catalytic activity;P:fatty acid metabolic process, metabolic process;C:cellular_component unknown;BOMFPAO.I.H.G.
At4g31500829277CYP83B1 (CYTOCHROME P450 MONOOXYGENASE 83B1)Encodes an oxime-metabolizing enzyme in the biosynthetic pathway of glucosinolates. Is required for phytochrome signal transduction in red light. Mutation confers auxin overproduction.O.I.H.G.
At4g32540829389YUC1 (YUCCA 1)Mutant has elevated levels of free IAA in dominant mutant allele; Flavin Monooxygenase-Like Enzyme; Auxin BiosynthesisO.I.H.G.
At4g34240829573ALDH3I1 (ALDEHYDE DEHYDROGENASE 3|1)Aldehyde dehydrogenase induced by ABA and dehydrationO.I.H.G.
At4g35090829661CAT2 (CATALASE 2)Encodes a peroxisomal catalase, highly expressed in bolts and leaves. mRNA expression patterns show circadian regulation with mRNA levels being high in the subjective early morning. Loss of function mutations have increased H2O2 levels and increased H2O2 sensitivity. Mutants accumulate more toxic ions yet show decreased sensitivity to Li+. This decreased sensitivity is most likely due to an insensitivity to ethylene. Note that in Queval et al. (2007) Plant Journal, 52(4):640, SALK_057998 is named as cat2-1, SALK_076998 is named as cat2-2; in Bueso et al. (2007) Plant Journal, 52(6):1052, SALK_076998 is named as cat2-1. TAIR has adopted the nomenclature consistent with that in Bueso et al. (2007) after consultation with the authors: SALK_076998 (cat2-1), SALK_057998 (cat2-2).O.I.H.G.
At4g39950830154CYP79B2Belongs to cytochrome P450 and is involved in tryptophan metabolism. Converts Trp to indo-3-acetaldoxime (IAOx), a precursor to IAA and indole glucosinolates.O.I.H.G.
At5g11320831003YUC4 (YUCCA4)Belongs to the YUC gene family. Encodes a predicted flavin monooxygenase YUC4 involved in auxin biosynthesis and plant development.O.I.H.G.
At5g20960832221AAO1 (ARABIDOPSIS ALDEHYDE OXIDASE 1)Encodes aldehyde oxidase AA01.O.I.H.G.
At5g22300832290NIT4 (NITRILASE 4)encodes a nitrilase isomer. The purified enzyme shows a strong substrate specificity for beta-cyano-L-alanine, a intermediate product of the cyanide detoxification pathway.O.I.H.G.
At5g25620832638YUC6 (YUCCA6)F:NADP or NADPH binding, oxidoreductase activity, monooxygenase activity, FAD binding, flavin-containing monooxygenase activity;P:auxin biosynthetic process;C:unknown;BOFMPAO.I.H.G.
At5g43890834411YUCCA5Encodes a YUCCA-like putative flavin monooxygenase, the activation tagging mutant has increased level of IAA, increased auxin response and phenotype of auxin overproduction, rescues erecta mutant phenotypeO.I.H.G.
At5g48230834876ACAT2 (ACETOACETYL-COA THIOLASE 2)F:acetyl-CoA C-acetyltransferase activity, catalytic activity;P:embryonic development ending in seed dormancy;C:peroxisome, plasma membrane;BOMFAPO.I.H.G.
At5g54960835587PDC2 (pyruvate decarboxylase-2)pyruvate decarboxylase-2O.I.H.G.
At5g657508367042-oxoglutarate dehydrogenase E1 component, putative / oxoglutarate decarboxylase, putative / alpha-ketoglutaric dehydrogenase, putativeF:oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor, oxoglutarate dehydrogenase (succinyl-transferring) activity, thiamin pyrophosphate binding;P:response to cadmium ion;C:mitochondrion;OBMFPAO.I.H.G.

Comparison with co-expressed genes



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