Metabolic pathway to genes

Genes assigned in the pathway

Query pathway ID 00053
Pathway name Ascorbate and aldarate metabolism
Organism Arabidopsis_thaliana
Database KEGG PATHWAY

Click Gene ID to show a list of co-expressed genes.

Gene ID Repr. ID Gene name Functional description O.I. H.G. Other DB
At1g07890837304APX1 (ascorbate peroxidase 1)Encodes a cytosolic ascorbate peroxidase APX1. Ascorbate peroxidases are enzymes that scavenge hydrogen peroxide in plant cells. Eight types of APX have been described for Arabidopsis: three cytosolic (APX1, APX2, APX6), two chloroplastic types (stromal sAPX, thylakoid tAPX), and three microsomal (APX3, APX4, APX5) isoforms. At least part of the induction of heat shock proteins during light stress in Arabidopsis is mediated by H2O2 that is scavenged by APX1. Expression of the gene is downregulated in the presence of paraquat, an inducer of photoxidative stress.O.I.H.G.
At1g14520838014MIOX1 (MYO-INISITOL OXYGENASE)Encodes MIOX1. Belongs to myo-inositol oxygenase gene family.O.I.H.G.
At1g23800838991ALDH2B7Encodes a mitochondrial aldehyde dehydrogenase; nuclear gene for mitochondrial product.O.I.H.G.
At1g26570839197UGD1 (UDP-GLUCOSE DEHYDROGENASE 1)F:in 7 functions;P:metabolic process;C:endomembrane system;OBAMPFVO.I.H.G.
At1g33660840257peroxidase family proteinPseudogene of AT1G33660; peroxidase family proteinO.I.H.G.
At1g54100841849ALDH7B4 (Aldehyde Dehydrogenase 7B4)Aldehyde dehydrogenaseO.I.H.G.
At1g55570842006sks12 (SKU5 Similar 12)F:oxidoreductase activity, copper ion binding;P:unknown;C:endomembrane system;FBPMOAO.I.H.G.
At1g77490844085TAPX (THYLAKOIDAL ASCORBATE PEROXIDASE)Encodes a chloroplastic thylakoid ascorbate peroxidase tAPX. Ascorbate peroxidases are enzymes that scavenge hydrogen peroxide in plant cells. Eight types of APX have been described for Arabidopsis: three cytosolic (APX1, APX2, APX6), two chloroplastic types (stromal sAPX, thylakoid tAPX), and three microsomal (APX3, APX4, APX5) isoforms.O.I.H.G.
At2g19800816499MIOX2 (MYO-INOSITOL OXYGENASE 2)Encodes a myo-inositol oxygenase family gene.O.I.H.G.
At3g02870821206VTC4Encodes a L-galactose-1-phosphate phosphatase, involved in ascorbate biosynthesis.O.I.H.G.
At3g09640820121APX2 (ASCORBATE PEROXIDASE 2)Encodes a cytosolic ascorbate peroxidase APX2. Ascorbate peroxidases are enzymes that scavenge hydrogen peroxide in plant cells. Eight types of APX have been described for Arabidopsis: three cytosolic (APX1, APX2, APX6), two chloroplastic types (stromal sAPX, thylakoid tAPX), and three microsomal (APX3, APX4, APX5) isoforms.O.I.H.G.
At3g09940820155MDHAR (MONODEHYDROASCORBATE REDUCTASE)Encodes a member of the monodehydroascorbate reductase gene family. Critical for a mutualistic symbiosis between the host Arabidopsis and the root colonizing fungus Piriformospora indica.O.I.H.G.
At3g27820822402MDAR4 (MONODEHYDROASCORBATE REDUCTASE 4)Encodes a peroxisome membrane-bound monodehydroascorbate reductase, involved in the ascorbate-glutathione cycle which removes toxic H2O2O.I.H.G.
At3g29360822594UDP-glucose 6-dehydrogenase, putativeF:in 6 functions;P:metabolic process;C:cytosol, nucleus;OBAMPFVO.I.H.G.
At3g47930823948ATGLDH (L-GALACTONO-1,4-LACTONE DEHYDOROGENASE)L-Galactono-1,4-lactone dehydrogenase, catalyzes the final step of ascorbate biosynthesisO.I.H.G.
At3g48000823955ALDH2B4 (ALDEHYDE DEHYDROGENASE 2B4)Encodes a putative (NAD+) aldehyde dehydrogenase.O.I.H.G.
At3g52880824454monodehydroascorbate reductase, putativeEncodes a peroxisomal monodehydroascorbate reductase, involved in the ascorbate-glutathione cycle which removes toxic H2O2O.I.H.G.
At4g08390826396SAPX (STROMAL ASCORBATE PEROXIDASE)Encodes a chloroplastic stromal ascorbate peroxidase sAPX. Ascorbate peroxidases are enzymes that scavenge hydrogen peroxide in plant cells. Eight types of APX have been described for Arabidopsis: three cytosolic (APX1, APX2, APX6), two chloroplastic types (stromal sAPX, thylakoid tAPX), and three microsomal (APX3, APX4, APX5) isoforms.O.I.H.G.
At4g09010826480APX4 (ASCORBATE PEROXIDASE 4)Encodes a microsomal ascorbate peroxidase APX4. Ascorbate peroxidases are enzymes that scavenge hydrogen peroxide in plant cells. Eight types of APX have been described for Arabidopsis: three cytosolic (APX1, APX2, APX6), two chloroplastic types (stromal sAPX, thylakoid tAPX), and three microsomal (APX3, APX4, APX5) isoforms.O.I.H.G.
At4g26260828732MIOX4Encodes a myo-inositol oxygenase.O.I.H.G.
At4g26850828792VTC2 (vitamin c defective 2)Encodes a novel protein involved in ascorbate biosynthesis, which was shown to catalyze the transfer of GMP from GDP-galactose to a variety of hexose-1-phosphate acceptors. Recessive mutation has a reduced amount of vitamin C, lower level of non-photochemical quenching, and reduced rate of conversion of violaxanthin to zeaxanthin in high light.O.I.H.G.
At4g32320829366APX6Encodes a cytosolic ascorbate peroxidase APX6. Ascorbate peroxidases are enzymes that scavenge hydrogen peroxide in plant cells. Eight types of APX have been described for Arabidopsis: three cytosolic (APX1, APX2, APX6), two chloroplastic types (stromal sAPX, thylakoid tAPX), and three microsomal (APX3, APX4, APX5) isoforms.O.I.H.G.
At4g33670829509L-galactose dehydrogenase (L-GalDH)Encodes a L-galactose dehydrogenase, involved in ascorbate biosynthesisO.I.H.G.
At4g34240829573ALDH3I1 (ALDEHYDE DEHYDROGENASE 3|1)Aldehyde dehydrogenase induced by ABA and dehydrationO.I.H.G.
At4g35000829652APX3 (ASCORBATE PEROXIDASE 3)Encodes a microsomal ascorbate peroxidase APX3. Ascorbate peroxidases are enzymes that scavenge hydrogen peroxide in plant cells. Eight types of APX have been described for Arabidopsis: three cytosolic (APX1, APX2, APX6), two chloroplastic types (stromal sAPX, thylakoid tAPX), and three microsomal (APX3, APX4, APX5) isoforms. The APX3 protein interacts with AKR2 (ankyrin-containing protein that interacts with AFT1) and AFT1, a 14-3-3 protein.O.I.H.G.
At4g35970829751APX5 (ASCORBATE PEROXIDASE 5)Encodes a microsomal ascorbate peroxidase APX5. Ascorbate peroxidases are enzymes that scavenge hydrogen peroxide in plant cells. Eight types of APX have been described for Arabidopsis: three cytosolic (APX1, APX2, APX6), two chloroplastic types (stromal sAPX, thylakoid tAPX), and three microsomal (APX3, APX4, APX5) isoforms.O.I.H.G.
At5g03630831774ATMDAR2F:monodehydroascorbate reductase (NADH) activity;P:response to cadmium ion, response to salt stress;C:cytosol;BOMFPAO.I.H.G.
At5g15490831402UDP-glucose 6-dehydrogenase, putativeF:in 7 functions;P:metabolic process;C:cytosol, cell wall, nucleus;OBAMPFVO.I.H.G.
At5g21100832234L-ascorbate oxidase, putativeF:oxidoreductase activity, copper ion binding, L-ascorbate oxidase activity;P:oxidation reduction;C:plant-type cell wall;BFPMOAO.I.H.G.
At5g28840833002GME (GDP-D-MANNOSE 3',5'-EPIMERASE)Encodes a protein with GDP-D-mannose 3',5'-epimerase activity. The enzyme is involved in ascorbate biosynthesis. It catalyzes the conversion of GDP-D-mannose to GDP-L-galactose.O.I.H.G.
At5g39320833928UDP-glucose 6-dehydrogenase, putativeF:in 6 functions;P:metabolic process;C:cytosol, nucleus;OBAMPFVO.I.H.G.
At5g56640835765MIOX5Myo-Inositol Oxygenase gene familyO.I.H.G.

Comparison with co-expressed genes



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