Biological process to genes

Query process ID GO:0006289
Process name A DNA repair process in which a small region of the strand surrounding the damage is removed from the DNA helix as an oligonucleotide. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase. Nucleotide excision repair recognizes a wide range of substrates, including damage caused by UV irradiation (pyrimidine dimers and 6-4 photoproducts) and chemicals (intrastrand cross-links and bulky adducts).
Organism Oryza sativa

Click Gene ID to show a list of co-expressed genes.

ECC Gene ID Repr. ID Gene name Functional descriptionEvAGI codeArabidopsis gene name O.I. H.G. Other DB
LOs01g0592900AK102072.1-The start codon is not identified.5e-4At1g79950helicase-relatedO.I.H.G.
LOs02g0179300AK069065.1-RAD23 protein, isoform II9e-10At1g16190DNA repair protein RAD23, putativeO.I.H.G.
LOs04g0397100---0--O.I.H.G.
LOs04g0397500AU174699-Myb, DNA-binding domain containing protein2e-1At2g25670unknown proteinO.I.H.G.
LOs05g0144800AK099724.1-TFIIH basal transcription factor complex helicasesubunit (EC 3.6.1.-) (DNA-repair protein complementingXP-D cells) (Xeroderma pigmentosum group D complementingprotein) (CXPD) (DNA excision repair protein ERCC-2)3e-38At1g03190UVH6 (ULTRAVIOLET HYPERSENSITIVE 6)O.I.H.G.
LOs05g0219800AK102822.1-DEAH helicase isoform 61e-4At1g79890helicase-relatedO.I.H.G.
LOs06g0264300AK061556.1-UV excision repair protein Rad23 family protein1e-12At3g02540RAD23-3 (PUTATIVE DNA REPAIR PROTEIN RAD23-3)O.I.H.G.
LOs08g0172200AK101266.1-UvrB/UvrC protein domain containing protein2e-1At2g11910unknown proteinO.I.H.G.
LOs08g0427500AK102608.1-DNA repair protein Rad4 family protein2e-6At5g16630RAD4O.I.H.G.
LOs08g0430200AK063768.1-OsRAD236e-20At5g38470DNA repair protein RAD23, putativeO.I.H.G.
LOs08g0516000---0--O.I.H.G.



The upper GO terms

Process ID Gene number Process name
GO:000628138The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.



The lower GO terms

Process ID Gene number Process name
GO:00007150The identification of lesions in DNA, such as pyrimidine-dimers, intrastrand cross-links, and bulky adducts. The wide range of substrate specificity suggests the repair complex recognizes distortions in the DNA helix.
GO:00007170The unwinding, or local denaturation, of the DNA duplex to create a bubble around the site of the DNA damage.
GO:00007180The removal of the oligonucleotide that contains the DNA damage. The oligonucleotide is formed by dual incisions that flank the site of DNA damage.
GO:00007200The repair of UV-induced T-T, C-T, and C-C dimers by the recognition and removal of the damaged DNA strand from the DNA helix as an oligonucleotide. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase.
GO:00062830The nucleotide-excision repair process that carries out preferential repair of DNA lesions on the actively transcribed strand of the DNA duplex. In addition, the transcription-coupled nucleotide-excision repair pathway is required for the recognition and repair of a small subset of lesions that are not recognized by the global genome nucleotide excision repair pathway.
GO:00062930The stabilization of the multiprotein complex involved in damage recognition, DNA helix unwinding, and endonucleolytic cleavage at the site of DNA damage as well as the unwound DNA. The stabilization of the protein-DNA complex ensures proper positioning of the preincision complex before the phosphodiester backbone of the damaged strand is cleaved 3' and 5' of the site of DNA damage.
GO:00062940The aggregation, arrangement and bonding together of proteins on DNA to form the multiprotein complex involved in damage recognition, DNA helix unwinding, and endonucleolytic cleavage at the site of DNA damage. This assembly occurs before the phosphodiester backbone of the damaged strand is cleaved 3' and 5' of the site of DNA damage.
GO:00062970Repair of the gap in the DNA helix by DNA polymerase and DNA ligase after the portion of the strand containing the lesion has been removed by pyrimidine-dimer repair enzymes.
GO:00336830A process that results in the endonucleolytic cleavage of the damaged strand of DNA. The incision occurs at the junction of single-stranded DNA and double-stranded DNA that is formed when the DNA duplex is unwound.
GO:00709110The nucleotide-excision repair process by which DNA lesions are removed from nontranscribed strands and from transcriptionally silent regions over the entire genome.





Comparison with co-expressed genes



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