Biological process to genes

Query process ID GO:0006099
Process name A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle.
Organism Oryza sativa

Click Gene ID to show a list of co-expressed genes.

ECC Gene ID Repr. ID Gene name Functional descriptionEvAGI codeArabidopsis gene name O.I. H.G. Other DB
COs01g0649100AF444195.1-Malate dehydrogenase1e-33At1g53240malate dehydrogenase (NAD), mitochondrialO.I.H.G.
COs01g0758300AK070480.1-Phosphoenolpyruvate carboxylase, housekeepingisozyme (EC (PEPCase)3e-60At1g53310ATPPC1 (PHOSPHOENOLPYRUVATE CARBOXYLASE 1)O.I.H.G.
COs01g0760600D10968.1-Aspartate aminotransferase, cytoplasmic (EC2.6.1.1) (Transaminase A)1e-3At1g62800ASP4 (ASPARTATE AMINOTRANSFERASE 4)O.I.H.G.
COs02g0244700AF271995.1-Phosphoenolpyruvate carboxylase 1 (EC 1) (CP21)5e-53At3g14940ATPPC3 (PHOSPHOENOLPYRUVATE CARBOXYLASE 3)O.I.H.G.
COs08g0120000AB017427.1-Succinate dehydrogenase iron-protein subunit(SDHB)7e-1At2g34520RPS14 (mitochondrial ribosomal protein S14)O.I.H.G.
COs12g0632700D85763.1--2e-16At5g09660PMDH2 (peroxisomal NAD-malate dehydrogenase 2)O.I.H.G.
LOs01g0276100AK059596.1-3-isopropylmalate dehydrogenase, chloroplastprecursor (EC (Beta-IPM dehydrogenase) (IMDH)(3-IPM-DH)2e-75At5g03290isocitrate dehydrogenase, putative / NAD+ isocitrate dehydrogenase, putativeO.I.H.G.
LOs02g0121800AK103260.1-Conserved hypothetical protein2e+0At4g13380MEE56 (maternal effect embryo arrest 56)O.I.H.G.
LOs02g0595500AK073096.1-NAD-dependent isocitrate dehydrogenase precursor(EC (ISOCITRATE DEHYDROGENASE 1)O.I.H.G.
LOs04g0394200AK068154.1-Rattus norvegicus DLST dihydrolipoamidesuccinyltransferase, exon 15 and complete cds1e-39At5g550702-oxoacid dehydrogenase family proteinO.I.H.G.
LOs04g0479300AK106088.1-Conserved hypothetical protein2e+0At4g11870unknown proteinO.I.H.G.
LOs04g0551200AK059248.1-Cytosolic malate dehydrogenase7e-1At1g04410malate dehydrogenase, cytosolic, putativeO.I.H.G.
LOs04g0551500AK068749.1-SBP domain containing protein3e-3At3g06410nucleic acid binding / zinc ion bindingO.I.H.G.
LOs05g0574400AK073698.1-Malate dehydrogenase6e-35At3g15020malate dehydrogenase (NAD), mitochondrial, putativeO.I.H.G.
LOs07g0521000AK058482.1-Succinate dehydrogenase subunit 31e+0At5g59840Ras-related GTP-binding family proteinO.I.H.G.
LOs07g0630800AK068064.1-Lactate/malate dehydrogenase family protein1e-3At2g22780PMDH1 (PEROXISOMAL NAD-MALATE DEHYDROGENASE 1)O.I.H.G.
LOs08g0366000AY187619.1-Phosphoenolpyruvate carboxylase 2 (EC 2) (CP28)1e-72At3g14940ATPPC3 (PHOSPHOENOLPYRUVATE CARBOXYLASE 3)O.I.H.G.
LOs08g0434300AK058477.1-Malate dehydrogenase precursor (EC (MALATE DEHYDROGENASE)O.I.H.G.
LOs08g0562100AK105935.1-Sorghum chloroplast CM3 malate dehydrogenase(NADP) (Fragment)7e-20At5g58330malate dehydrogenase (NADP), chloroplast, putativeO.I.H.G.
LOs09g0370300AK108199.1-Succinate dehydrogenase iron-sulfur subunit (EC1.3.99.1) (Fragment)3e-2At5g65165SDH2-3O.I.H.G.
LOs10g0478200AK104691.1-Cytosolic malate dehydrogenase (EC dehydrogenase, cytosolic, putativeO.I.H.G.

The upper GO terms

Process ID Gene number Process name
GO:00090603The enzymatic release of energy from organic compounds (especially carbohydrates and fats) which requires oxygen as the terminal electron acceptor.
GO:00463560The chemical reactions and pathways resulting in the breakdown of acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated.

The lower GO terms

Process ID Gene number Process name
GO:00196430A pathway leading to the fixation of two molecules of CO2 and the production of one molecule of acetyl-CoA; essentially the oxidative TCA cycle running in reverse. Acetyl-CoA is reductively carboxylated to pyruvate, from which all other central metabolites can be formed. Most of the enzymes of reductive and oxidative TCA cycle are shared, with the exception of three key enzymes that allow the cycle to run in reverse: ATP citrate lyase, 2-oxoglutarate:ferredoxin oxidoreductase, and fumarate reductase. 2-oxoglutarate:ferredoxin oxidoreductase catalyzes the carboxylation of succinyl-CoA to 2-oxoglutarate, ATP citrate lyase the ATP-dependent cleavage of citrate to acetyl-CoA and oxaloacetate, and fumarate reductase the reduction of fumarate forming succinate.

Comparison with co-expressed genes

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