Gene omics information

Query gene ID At5g44070
Gene name CAD1 (CADMIUM SENSITIVE 1)
Organism Arabidopsis thaliana


Co-expressed genes



As this page just shows up to 10 genes to the query, if you wish to have the complete list of co-expressed genes, click Gene/Probe ID.

VF%ileGene/Probe IDRepr.IDGene NameFunctional DescriptionS.X.H.G.Other DB
0.3846.7At5g44070834430CAD1 (CADMIUM SENSITIVE 1)Phytochelatin synthase gene confers tolerance to cadmium ions. Catalyzes phytochelatin (PC) synthesis from glutathione (GSH) in the presence of Cd2+, Zn2+, Cu2+ and Fe3+, but not by Co2+ or Ni2+.S.X.H.G.
0.7184.2At1g28380839735NSL1 (necrotic spotted lesions 1)This gene is predicted to encode a protein involved in negatively regulating salicylic acid-related defense responses and cell death programs. nsl1 mutants develop necrotic lesions spontaneously and show other features of a defense response, such as higher levels of SA and disease resistance-related transcripts, in the absence of a biotic stimulus. The NSL1 protein is predicted to have a MACPF domain, found in proteins that form a transmembrane pore in mammalian immune responses. NSL1 transcript levels do not appear to change in response to biotic stresses, but are elevated by cycloheximide in seedlings, and by sodium chloride in roots.S.X.H.G.
0.5974.7At3g59080825077aspartyl protease family proteinF:DNA binding, aspartic-type endopeptidase activity;P:proteolysis;C:endomembrane system;PMFOS.X.H.G.
0.5873.8At2g01180814646ATPAP1 (PHOSPHATIDIC ACID PHOSPHATASE 1)Encodes phosphatidate phosphatase. Up-regulated by genotoxic stress (gamma ray or UV-B) and elicitor treatments with mastoparan and harpin. Expressed in roots and leaves.S.X.H.G.
0.5673.0At1g29690839846CAD1 (constitutively activated cell death 1)Encodes a protein containing a domain with significant homology to the MACPF (membrane attack complex and perforin) domain of complements and perforin proteins that are involved in innate immunity in animals. Transgenic cad1-1 mutant plants show lesions seen in the hypersensitive response, as well as a spontaneous activation of expression of pathogenesis-related genes and leading to a 32-fold increase in salicylic acid (SA). CAD1 is postulated to act as a negative regulator controlling SA-mediated pathway of programmed cell death in plant immunity.S.X.H.G.
0.5570.6At1g27770839670ACA1 (AUTO-INHIBITED CA2+-ATPASE 1)Encodes a chloroplast envelope Ca2+-ATPase with an N-terminal autoinhibitor.S.X.H.G.
0.5570.6At5g47910834842RBOHD (RESPIRATORY BURST OXIDASE HOMOLOGUE D)NADPH/respiratory burst oxidase protein D (RbohD).Interacts with AtrbohF gene to fine tune the spatial control of ROI production and hypersensitive response to cell in and around infection site.S.X.H.G.
0.5469.5At1g55450841992embryo-abundant protein-relatedF:methyltransferase activity;P:response to salt stress;C:unknown;BPFMOAS.X.H.G.
0.5368.6At3g09830820141protein kinase, putativeF:protein kinase activity, kinase activity, ATP binding;P:protein amino acid phosphorylation;C:plasma membrane;MPOBFVAS.X.H.G.
0.5267.4At4g39640830118GGT1 (GAMMA-GLUTAMYL TRANSPEPTIDASE 1)The gene encodes a gamma-glutamyltransferase (AKA gamma-glutamyl transpeptidase, EC 2.3.2.2) that is located in vascular tissues (predominantly phloem) of leaves and is involved in the degradation of glutathione. The encoded enzyme also mitigates oxidative stress by metabolizing GSSG (oxidized form of GSH - glutathione) in the apoplast.S.X.H.G.
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Specifically expressed experiments



As this page just shows up to 10 assays to the query, if you wish to have the complete list of assays that the query gene/probe was specifically expressed, click here.
Std2 GX%ileGSM IDAssay NameGSE IDExperiment Title
52.399.8GSM184520Pericycle root cells 2hr continuous KNO3 and MSX treated, biological rep2GSE7631Cell-specific nitrogen responses in the Arabidopsis root
50.799.8E-NASC-76-raw-cel-1359879106
44.399.8E-NASC-76-raw-cel-1359878951
43.499.8E-NASC-76-raw-cel-1359879132
33.499.7GSM13783Dexamethasone plus cycloheximide - replicateGSE911Identification of LEAFY targets during reproductive transition
32.899.7GSM184516Pericycle root cells 2hr continuous KCl and MSX control treated, biological rep1GSE7631Cell-specific nitrogen responses in the Arabidopsis root
32.399.7E-NASC-76-raw-cel-1359879028
30.599.7GSM13784Cycloheximide - replicateGSE911Identification of LEAFY targets during reproductive transition
30.199.7GSM184519Pericycle root cells 2hr continuous KNO3 and MSX treated, biological rep1GSE7631Cell-specific nitrogen responses in the Arabidopsis root
29.499.7GSM269830T6 leaf-well watered-rep3GSE10670Global expression profiling of wild type and transgenic Arabidopsis plants in response to water stress
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Homologous genes



Paralogous genes



Click Gene ID to show a list of homologous genes.

HFEvBSGene IDRepr. IDGene NameFunctional descriptionC.G.S.X.Other DB
0.780837At1g03980839354ATPCS2 (phytochelatin synthase 2)Encodes a protein with phytochelatin synthase activity which binds Cd2+ and Cd-glutathione complexes with high affinity. The protein has been postulated to be involved in Cd2+ tolerance. AtPCS2 expression appears to be less than that of AtPCS1, explaining the inability of endogenous AtPCS2 to substitute for AtPCS1 in the cad1-3 mutant (AtPCS1 null).C.G.S.X.
0.012e-138At3g63440825519CKX6 (CYTOKININ OXIDASE/DEHYDROGENASE 6)This gene used to be called AtCKX7. It encodes a protein whose sequence is similar to cytokinin oxidase/dehydrogenase, which catalyzes the degradation of cytokinins.C.G.S.X.
0.022e-138At3g54390824605transcription factorF:transcription factor activity;P:regulation of transcription;C:cellular_component unknown;PBFOMC.G.S.X.
0.017e-136At5g18450831963AP2 domain-containing transcription factor, putativeencodes a member of the DREB subfamily A-2 of ERF/AP2 transcription factor family. The protein contains one AP2 domain. There are eight members in this subfamily including DREB2A AND DREB2B that are involved in response to drought.C.G.S.X.
0.017e-136At5g09950830856pentatricopeptide (PPR) repeat-containing proteinF:unknown;P:unknown;C:unknown;POFMBC.G.S.X.
0.017e-136At3g15380820777choline transporter-relatedF:unknown;P:biological_process unknown;C:plasma membrane;MOFPC.G.S.X.
0.017e-136At2g43960819001SWAP (Suppressor-of-White-APricot)/surp domain-containing proteinF:RNA binding;P:RNA processing;C:cellular_component unknown;PMFOC.G.S.X.
0.017e-136At1g33390840232helicase domain-containing proteinF:helicase activity, ATP binding, ATP-dependent helicase activity, nucleic acid binding;P:biological_process unknown;C:cellular_component unknown;BMOFPVC.G.S.X.
0.027e-136At1g13620837923unknown proteinF:molecular_function unknown;P:biological_process unknown;C:endomembrane system;PC.G.S.X.
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Orthologous genes



Click Gene ID to show a list of orthologous genes.

HFEvBSSpeciesGene IDRepr. IDGene NameFunctional descriptionEvAGI codeArabidopsis gene nameC.G.S.X.Other DB
0.157e-1169Glycine maxGma.8452.1.S1_s_atAF411075.1homo-phytochelatin synthase-7e-11At5g44070CAD1 (CADMIUM SENSITIVE 1)C.G.S.X.
0.024e-136Hordeum vulgareHVSMEf0011G04r2_atHVSMEf0011G04r2--3e-4At4g19003VPS25C.G.S.X.
0.024e-138Oryza sativaOs06g0102300AK071754.1-Phytochelatin synthase1e-3At1g03980ATPCS2 (phytochelatin synthase 2)C.G.S.X.
0.289e-26119Populus trichocarpaPtpAffx.212040.1.S1_atpmrna23633hypothetical protein-7e-26At5g44070CAD1 (CADMIUM SENSITIVE 1)C.G.S.X.
0.028e-136Triticum aestivumTaAffx.12743.1.A1_atBJ238339--4e+0At3g42790AL3 (ALFIN-LIKE 3)C.G.S.X.
0.028e-134Vitis vinifera1615654_atCF211462hypothetical protein LOC100254037-7e-14At1g58440XF1C.G.S.X.
0.025e+032Zea maysZmAffx.262.1.A1_s_atAI670379acidic ribosomal protein P3-3e+0At4g27410RD26 (RESPONSIVE TO DESICCATION 26)C.G.S.X.
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Biological processes



Click GO ID to show a list of genes that are associated with the GO ID.

ECCGO IDProcess Name
XGO:0042344The chemical reactions and pathways resulting in the breakdown of indole glucosinolates, sulfur-containing compounds that have a common structure linked to an R group derived from tryptophan.
XGO:0042742Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.
XGO:0052544Any process by which callose is transported to, and/or maintained in, the cell wall during the defense response. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls.
XGO:0046685A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenic stimulus from compounds containing arsenic, including arsenates, arsenites, and arsenides.
XGO:0046686A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.
XGO:0046938The chemical reactions and pathways resulting in the formation of phytochelatins, any of a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes. The structure is of the type (gamma-glutamyl-cysteinyl)n-glycine, where n is 2 to 11.
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Metabolic pathways



Click KaPPA-View ID to show a list of genes that are assigned to the KaPPA-View ID.

KaPPA-View IDLink to Kappa-ViewPathway Name



Click KEGG PATHWAY ID to show a list of genes that are assigned to the KEGG PATHWAY ID.

KEGG PATHWAY IDLink to KEGG PATHWAYPathway Name
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