Gene omics information

Query gene ID At1g29690
Gene name CAD1 (constitutively activated cell death 1)
Organism Arabidopsis thaliana

Co-expressed genes

As this page just shows up to 10 genes to the query, if you wish to have the complete list of co-expressed genes, click Gene/Probe ID.

VF%ileGene/Probe IDRepr.IDGene NameFunctional DescriptionS.X.H.G.Other DB
0.5773.8At1g29690839846CAD1 (constitutively activated cell death 1)Encodes a protein containing a domain with significant homology to the MACPF (membrane attack complex and perforin) domain of complements and perforin proteins that are involved in innate immunity in animals. Transgenic cad1-1 mutant plants show lesions seen in the hypersensitive response, as well as a spontaneous activation of expression of pathogenesis-related genes and leading to a 32-fold increase in salicylic acid (SA). CAD1 is postulated to act as a negative regulator controlling SA-mediated pathway of programmed cell death in plant immunity.S.X.H.G.
0.8089.8At4g39640830118GGT1 (GAMMA-GLUTAMYL TRANSPEPTIDASE 1)The gene encodes a gamma-glutamyltransferase (AKA gamma-glutamyl transpeptidase, EC that is located in vascular tissues (predominantly phloem) of leaves and is involved in the degradation of glutathione. The encoded enzyme also mitigates oxidative stress by metabolizing GSSG (oxidized form of GSH - glutathione) in the apoplast.S.X.H.G.
0.7385.5At4g34150829563C2 domain-containing proteinF:unknown;P:response to cold;C:unknown;MPFOBVAS.X.H.G.
0.7184.2At1g28380839735NSL1 (necrotic spotted lesions 1)This gene is predicted to encode a protein involved in negatively regulating salicylic acid-related defense responses and cell death programs. nsl1 mutants develop necrotic lesions spontaneously and show other features of a defense response, such as higher levels of SA and disease resistance-related transcripts, in the absence of a biotic stimulus. The NSL1 protein is predicted to have a MACPF domain, found in proteins that form a transmembrane pore in mammalian immune responses. NSL1 transcript levels do not appear to change in response to biotic stresses, but are elevated by cycloheximide in seedlings, and by sodium chloride in roots.S.X.H.G.
0.6781.6At3g09830820141protein kinase, putativeF:protein kinase activity, kinase activity, ATP binding;P:protein amino acid phosphorylation;C:plasma membrane;MPOBFVAS.X.H.G.
0.5570.6At3g45640823706ATMPK3 (ARABIDOPSIS THALIANA MITOGEN-ACTIVATED PROTEIN KINASE 3)Encodes a mitogen-activated kinase whose mRNA levels increase in response to touch, cold, salinity stress and chitin oligomers.Also functions in ovule development. Heterozygous MPK3 mutants in a homozygous MPK6 background are female sterile due to defects in integument development. MPK3 can be dephosphorylated by MKP2 in vitro.S.X.H.G.
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Specifically expressed experiments

As this page just shows up to 10 assays to the query, if you wish to have the complete list of assays that the query gene/probe was specifically expressed, click here.
Std2 GX%ileGSM IDAssay NameGSE IDExperiment Title
83.099.9GSM13779Dexamethasone plus cycloheximideGSE911Identification of LEAFY targets during reproductive transition
79.099.9GSM13784Cycloheximide - replicateGSE911Identification of LEAFY targets during reproductive transition
63.199.8GSM13780CycloheximideGSE911Identification of LEAFY targets during reproductive transition
59.899.8GSM13783Dexamethasone plus cycloheximide - replicateGSE911Identification of LEAFY targets during reproductive transition
54.199.8GSM131321AtGen_6-3421_Saltstress-Roots-6.0h_Rep1GSE5623AtGenExpress: Stress Treatments (Salt stress)
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Homologous genes

Paralogous genes

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HFEvBSGene IDRepr. IDGene NameFunctional descriptionC.G.S.X.Other DB
0.011e-242At3g54080824575sugar bindingF:sugar binding;P:biological_process unknown;C:endomembrane system;PBC.G.S.X.
0.012e-138At4g34100829556protein binding / zinc ion bindingF:protein binding, zinc ion binding;P:unknown;C:chloroplast;MPOFVC.G.S.X.
0.018e-136At2g41410818739calmodulin, putativeF:calcium ion binding;P:unknown;C:plasma membrane;MPFOBC.G.S.X.
0.018e-136At1g04090839298unknown proteinF:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;PFBMOC.G.S.X.
0.018e-136At1g49190841342ARR19 (ARABIDOPSIS RESPONSE REGULATOR 19)member of Response Regulator: B- TypeC.G.S.X.
0.018e-136At1g18350838416ATMKK7MAP kinase kinase7. Member of plant mitogen-activated protein kinase kinase group D. Negative regulator of polar auxin transport. Overexpression leads to activation of basal and systemic acquired resistance.C.G.S.X.
0.018e-136At1g56145842067leucine-rich repeat family protein / protein kinase family proteinF:protein binding, protein serine/threonine kinase activity, protein kinase activity, ATP binding;P:protein amino acid phosphorylation;C:plasma membrane;PMOBFVAC.G.S.X.
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Orthologous genes

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HFEvBSSpeciesGene IDRepr. IDGene NameFunctional descriptionEvAGI codeArabidopsis gene nameC.G.S.X.Other DB
0.266e-1893Glycine maxGma.4262.1.S1_atCD406832--4e-18At1g29690CAD1 (constitutively activated cell death 1)C.G.S.X.
0.127e-961Hordeum vulgareContig13528_atContig13528--9e-9At1g29690CAD1 (constitutively activated cell death 1)C.G.S.X.
0.024e-448Oryza sativaOsAffx.21623.1.S1_at---0C.G.S.X.
0.253e-1377Populus trichocarpaPtpAffx.55857.1.A1_atCV244535hypothetical protein-2e-13At1g29690CAD1 (constitutively activated cell death 1)C.G.S.X.
0.096e-1169Triticum aestivumTa.12913.1.S1_atCA741662--7e-11At1g29690CAD1 (constitutively activated cell death 1)C.G.S.X.
0.021e+034Vitis vinifera1610917_atCD715674--2e-2At3g14670unknown proteinC.G.S.X.
0.042e-859Zea maysZm.3750.1.A1_atCO517698MAC/Perforin domain containing protein-3e-8At1g29690CAD1 (constitutively activated cell death 1)C.G.S.X.
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Biological processes

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ECCGO IDProcess Name
XGO:0006955Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.
XGO:0008219The specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death.
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Metabolic pathways

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KaPPA-View IDLink to Kappa-ViewPathway Name

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