Gene omics information

Query gene ID At1g28380
Gene name NSL1 (necrotic spotted lesions 1)
Organism Arabidopsis thaliana

Co-expressed genes

As this page just shows up to 10 genes to the query, if you wish to have the complete list of co-expressed genes, click Gene/Probe ID.

VF%ileGene/Probe IDRepr.IDGene NameFunctional DescriptionS.X.H.G.Other DB
0.6378.1At1g28380839735NSL1 (necrotic spotted lesions 1)This gene is predicted to encode a protein involved in negatively regulating salicylic acid-related defense responses and cell death programs. nsl1 mutants develop necrotic lesions spontaneously and show other features of a defense response, such as higher levels of SA and disease resistance-related transcripts, in the absence of a biotic stimulus. The NSL1 protein is predicted to have a MACPF domain, found in proteins that form a transmembrane pore in mammalian immune responses. NSL1 transcript levels do not appear to change in response to biotic stresses, but are elevated by cycloheximide in seedlings, and by sodium chloride in roots.S.X.H.G.
0.9296.0At4g39640830118GGT1 (GAMMA-GLUTAMYL TRANSPEPTIDASE 1)The gene encodes a gamma-glutamyltransferase (AKA gamma-glutamyl transpeptidase, EC that is located in vascular tissues (predominantly phloem) of leaves and is involved in the degradation of glutathione. The encoded enzyme also mitigates oxidative stress by metabolizing GSSG (oxidized form of GSH - glutathione) in the apoplast.S.X.H.G.
0.8894.0At4g34150829563C2 domain-containing proteinF:unknown;P:response to cold;C:unknown;MPFOBVAS.X.H.G.
0.8089.8At3g09830820141protein kinase, putativeF:protein kinase activity, kinase activity, ATP binding;P:protein amino acid phosphorylation;C:plasma membrane;MPOBFVAS.X.H.G.
0.7586.9At3g52400824405SYP122 (SYNTAXIN OF PLANTS 122)syntaxin protein, involved in the negative regulation of defense pathways such as programmed cell death, salicylic acid signalling pathway, jasmonic acid signalling pathwayS.X.H.G.
0.7184.2At1g55450841992embryo-abundant protein-relatedF:methyltransferase activity;P:response to salt stress;C:unknown;BPFMOAS.X.H.G.
0.6378.1At1g29690839846CAD1 (constitutively activated cell death 1)Encodes a protein containing a domain with significant homology to the MACPF (membrane attack complex and perforin) domain of complements and perforin proteins that are involved in innate immunity in animals. Transgenic cad1-1 mutant plants show lesions seen in the hypersensitive response, as well as a spontaneous activation of expression of pathogenesis-related genes and leading to a 32-fold increase in salicylic acid (SA). CAD1 is postulated to act as a negative regulator controlling SA-mediated pathway of programmed cell death in plant immunity.S.X.H.G.
0.6176.7At3g45640823706ATMPK3 (ARABIDOPSIS THALIANA MITOGEN-ACTIVATED PROTEIN KINASE 3)Encodes a mitogen-activated kinase whose mRNA levels increase in response to touch, cold, salinity stress and chitin oligomers.Also functions in ovule development. Heterozygous MPK3 mutants in a homozygous MPK6 background are female sterile due to defects in integument development. MPK3 can be dephosphorylated by MKP2 in vitro.S.X.H.G.
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Specifically expressed experiments

As this page just shows up to 10 assays to the query, if you wish to have the complete list of assays that the query gene/probe was specifically expressed, click here.
Std2 GX%ileGSM IDAssay NameGSE IDExperiment Title
81.099.9GSM131322AtGen_6-3422_Saltstress-Roots-6.0h_Rep2GSE5623AtGenExpress: Stress Treatments (Salt stress)
80.899.9GSM131321AtGen_6-3421_Saltstress-Roots-6.0h_Rep1GSE5623AtGenExpress: Stress Treatments (Salt stress)
77.799.9GSM13780CycloheximideGSE911Identification of LEAFY targets during reproductive transition
67.199.8GSM13783Dexamethasone plus cycloheximide - replicateGSE911Identification of LEAFY targets during reproductive transition
66.899.8GSM13779Dexamethasone plus cycloheximideGSE911Identification of LEAFY targets during reproductive transition
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Homologous genes

Paralogous genes

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HFEvBSGene IDRepr. IDGene NameFunctional descriptionC.G.S.X.Other DB
0.022e-138At4g20380827786zinc finger protein (LSD1)LSD1 monitors a superoxide-dependent signal and negatively regulates a plant cell death pathway. contains zinc-finger motifs. LSD1 negatively regulates a basal defense pathway that can act upstream or independently of both NIM1/NPR1 function and SA accumulation following avirulent or virulent pathogen challengeC.G.S.X.
0.019e-136At5g15890831446unknown proteinF:unknown;P:biological_process unknown;C:unknown;PMFOVBAC.G.S.X.
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Orthologous genes

Click Gene ID to show a list of orthologous genes.

HFEvBSSpeciesGene IDRepr. IDGene NameFunctional descriptionEvAGI codeArabidopsis gene nameC.G.S.X.Other DB
0.028e-240Glycine maxGmaAffx.91343.1.S1_atCF807068--3e-4At4g24290-C.G.S.X.
0.012e+034Hordeum vulgareContig1221_x_atContig1221--5e+0At5g19140AILP1C.G.S.X.
0.045e-138Oryza sativaOs05g0557400AK069566.1-Membrane attack complexcomponent/perforin/complement C9 family protein3e-1At1g28380NSL1 (necrotic spotted lesions 1)C.G.S.X.
0.186e-1273Populus trichocarpaPtpAffx.203874.1.S1_atpmrna7654hypothetical protein-4e-12At1g28380NSL1 (necrotic spotted lesions 1)C.G.S.X.
0.021e+036Triticum aestivumTaAffx.57600.1.S1_atCA626678--2e-2At4g12440adenine phosphoribosyltransferase, putativeC.G.S.X.
0.021e+034Vitis vinifera1621779_s_atBQ794980hypothetical protein LOC100244148-6e-40At3g52560UEV1D-4 (UBIQUITIN E2 VARIANT 1D-4)C.G.S.X.
0.012e+034Zea maysZmAffx.485.1.S1_atAI691349--8e-1Atmg00140-C.G.S.X.
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Biological processes

Click GO ID to show a list of genes that are associated with the GO ID.

ECCGO IDProcess Name
XGO:0009626The rapid, localized death of plant cells in response to invasion by a pathogen.
XGO:0010337Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving salicylic acid.
XGO:0052542Any process by which callose is transported to, and/or maintained in, a specific location during the defense response. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls.
SGO:0009651A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
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Metabolic pathways

Click KaPPA-View ID to show a list of genes that are assigned to the KaPPA-View ID.

KaPPA-View IDLink to Kappa-ViewPathway Name

Click KEGG PATHWAY ID to show a list of genes that are assigned to the KEGG PATHWAY ID.

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