Homology analysis

Gene ID At4g36380
Gene name ROT3 (ROTUNDIFOLIA 3)
Functional description Encodes a cytochrome P-450 gene that is involved in leaf blade expansion by controlling polar cell expansion in the leaf length direction. Member of the CYP90C CYP450 family. ROT3 was shown to be involved in brassinosteroid biosynthesis, most likely in the conversion step of typhasterol (TY) to castasterone (CS). As 6-deoxo-CS was unable to restore the phenotype of rot3-1, it has been postulated that ROT3 might be specifically involved in the conversion of TY to CS in the C6-oxidation pathway of brassinolide. Recently, CYP90C1 was shown to catalyse the C-23 hydroxylation of several brassinosteroids (the enzyme has a broad specificity for 22-hydroxylated substrates).

Click gene/probe ID to show a list of genes that are homologous to the gene.

Paralogous genes

HFEvBSGene IDRepr. IDGene NameFunctional DescriptionO.I.C.G.S.X.Other DB
0.022e-448At5g05690830453CPD (CONSTITUTIVE PHOTOMORPHOGENIC DWARF)Encodes a member of the CP90A family, a cytochrome P450 monooxygenase which converts 6-deoxocathasterone to 6-deoxoteasterone in the late C6 oxidation pathway and cathasterone to teasterone in the early C6 oxidation pathway of brassinolide biosynthesis. Expressed in cotyledons and leaves. Mutants display de-etiolation and derepression of light-induced genes in the dark, dwarfism, male sterility and activation of stress-regulated genes in the light. The expression of the gene using a CPD promoter:LUC fusion construct was shown to be under circadian and light control. Additionally, the circadian regulation was shown to be independent of BR levels as it remains unchanged in bri1 mutant lines. CPD appears to be involved in the autonomous pathway that regulates the transition to flowering, primarily through a BRI1-mediated signaling pathway that affects FLC expression levels, as uncovered by double mutant analyses.O.I.C.G.S.X.
0.021e-242At5g64920836616CIP8 (COP1-INTERACTING PROTEIN 8)Encodes a RING-H2 protein that interacts with the RING finger domain of COP1. CIP8 exhibits a strong interaction with the E2 ubiquitin conjugating enzyme AtUBC8 through its N-terminal domain and promotes ubiquitination in an E2-dependent fashion in vitro. It is possible that the AtUBC8-CIP8 module might interact with COP1 in vivo, thereby participating in proteasome-mediated degradation of HY5.O.I.C.G.S.X.
0.021e-242At3g25165822108RALFL25 (ralf-like 25)Member of a diversely expressed predicted peptide family showing sequence similarity to tobacco Rapid Alkalinization Factor (RALF), and is believed to play an essential role in the physiology of Arabidopsis. Consists of a single exon and is characterized by a conserved C-terminal motif and N-terminal signal peptide.O.I.C.G.S.X.
0.021e-242At1g10700837613ribose-phosphate pyrophosphokinase 3 / phosphoribosyl diphosphate synthetase 3 (PRS3)F:magnesium ion binding, ribose phosphate diphosphokinase activity;P:cellular biosynthetic process, nucleotide biosynthetic process, nucleoside metabolic process, ribonucleoside monophosphate biosynthetic process;C:chloroplast;BOMFAPVO.I.C.G.S.X.
0.015e-240At5g17690831635TFL2 (TERMINAL FLOWER 2)Regulates the meristem response to light signals and the maintenance of inflorescence meristem identity. Influences developmental processes controlled by APETALA1. TFL2 silences specific genes within euchromatin but not genes positioned in heterochromatin. TFL2 protein localized preferentially to euchromatic regions and not to heterochromatic chromocenters. Involved in euchromatin organization. Required for epigenetic maintenance of the vernalized state.O.I.C.G.S.X.
0.025e-240At3g11290820300unknown proteinF:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;PFO.I.C.G.S.X.
0.025e-240At1g73870843723zinc finger (B-box type) family proteinF:transcription factor activity, zinc ion binding;P:regulation of transcription;C:intracellular;POO.I.C.G.S.X.

Orthologous genes

HFEvBSGene IDOrganismRepr. IDGene NameFunctional DescriptionEvAGI codeArabidopsis gene nameO.I.C.G.S.X.Other DB
0.031e+036GmaAffx.24451.1.A1_atGlycine maxBU550405--3e-1At4g36380ROT3 (ROTUNDIFOLIA 3)O.I.C.G.S.X.
0.031e-138HT10O19r_atHordeum vulgareHT10O19r--1e-2At5g59000zinc finger (C3HC4-type RING finger) family proteinO.I.C.G.S.X.
0.026e-344OsAffx.14631.1.S1_atOryza sativa---0O.I.C.G.S.X.
0.312e-1171PtpAffx.207389.1.S1_atPopulus trichocarpapmrna14661hypothetical protein-1e-11At4g36380ROT3 (ROTUNDIFOLIA 3)O.I.C.G.S.X.
0.023e+034TaAffx.129513.2.A1_x_atTriticum aestivumBJ306606--5e-18At1g07890APX1 (ascorbate peroxidase 1)O.I.C.G.S.X.
0.022e-1361622542_a_atVitis viniferaBQ796994oxalyl-CoA decarboxylase-like-5e-9At5g17380pyruvate decarboxylase family proteinO.I.C.G.S.X.
0.025e+032Zm.8674.1.A1_atZea maysBM332208--1e+0At1g66475unknown proteinO.I.C.G.S.X.



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