Homology analysis

Gene ID At3g25070
Functional description Encodes a member of the R protein complex and may represent a virulence target of type III pili effector proteins (virulence factors) from bacterial pathogens, which is 'guarded' by R protein complex (RPM1 and RPS2 proteins). RIN4 physically interacts with RPS2 and RPM1 in vivo. Bacterial avirulence (Avr) effectors AvrB, AvrRpm1, and AvrRpt2 induce a mobility shift in RIN4 and expression of AvrRpt2 induces rapid degradation of RIN4. RIN4 contains 2 sites for AvrRpt2 autocleavage, called RCS1 and RCS2. Overexpression of RIN4 inhibits multiple phenotypes associated with AvrRpt2 function and also inhibits PAMP-induced defense signaling. Attached to the plasma membrane at its carboxyl terminus. Cleaved by AvrRpt2 at two PxFGxW motifs, one releasing a large portion of RIN4 from the plasma membrane and both exposing amino-terminal residues that destabilized the carboxyl-terminal cleavage products by targeting them for N-end ubiquitylation and proteasomal degradation.

Click gene/probe ID to show a list of genes that are homologous to the gene.

Paralogous genes

HFEvBSGene IDRepr. IDGene NameFunctional DescriptionO.I.C.G.S.X.Other DB
0.022e-240At5g48800834938phototropic-responsive NPH3 family proteinF:protein binding, signal transducer activity;P:response to light stimulus;C:plasma membrane;PO.I.C.G.S.X.
0.023e-136At4g00980827935zinc knuckle (CCHC-type) family proteinF:zinc ion binding, nucleic acid binding;P:biological_process unknown;C:cellular_component unknown;PMFO.I.C.G.S.X.
0.023e-136At3g29200822573CM1 (CHORISMATE MUTASE 1)L-ascorbate peroxidaseO.I.C.G.S.X.
0.023e-136At1g30280839908heat shock protein bindingF:heat shock protein binding;P:unknown;C:cellular_component unknown;MOFPVBO.I.C.G.S.X.
0.013e-136At1g16130838182WAKL2 (wall associated kinase-like 2)wall-associated kinase likeO.I.C.G.S.X.
0.011e+034At5g15300831382pentatricopeptide (PPR) repeat-containing proteinF:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;POMFBO.I.C.G.S.X.
0.021e+034At5g64060836527anac103 (Arabidopsis NAC domain containing protein 103)F:transcription factor activity;P:multicellular organismal development, regulation of transcription;C:cellular_component unknown;PO.I.C.G.S.X.
0.011e+034At5g18360831954disease resistance protein (TIR-NBS-LRR class), putativeF:transmembrane receptor activity, protein binding, nucleoside-triphosphatase activity, nucleotide binding, ATP binding;P:signal transduction, defense response, apoptosis, innate immune response;C:intrinsic to membrane, chloroplast;PMBOFAVO.I.C.G.S.X.

Orthologous genes

HFEvBSGene IDOrganismRepr. IDGene NameFunctional DescriptionEvAGI codeArabidopsis gene nameO.I.C.G.S.X.Other DB
0.051e-138GmaAffx.11078.1.S1_atGlycine maxCA938779--1e-2At5g53486unknown proteinO.I.C.G.S.X.
0.031e-240Contig13170_s_atHordeum vulgareContig13170--3e-1At5g41700UBC8 (UBIQUITIN CONJUGATING ENZYME 8)O.I.C.G.S.X.
0.041e-242Os05g0299100Oryza sativa9633.m02074-Hypothetical protein4e-3At3g25070RIN4 (RPM1 INTERACTING PROTEIN 4)O.I.C.G.S.X.
0.111e-757Ptp.7016.1.S1_atPopulus trichocarpaAJ767112hypothetical protein-1e-7At3g25070RIN4 (RPM1 INTERACTING PROTEIN 4)O.I.C.G.S.X.
0.043e-136Ta.3957.3.S1_atTriticum aestivumBJ269306Dehydration-induced protein-1e+0At4g34270TIP41-like family proteinO.I.C.G.S.X.
0.041e+0321612068_atVitis viniferaCF405105--2e-16At5g62690TUB2O.I.C.G.S.X.
0.031e-136Zm.15253.1.A1_atZea maysBM351647--3e-1At1g17970zinc finger (C3HC4-type RING finger) family proteinO.I.C.G.S.X.

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