Homology analysis

Gene ID At3g10800
Gene name BZIP28
Functional description Encodes bZIP28, a putative membrane-tethered transcriptional factor. Up-regulated in response to heat; a bZIP28 null mutant has a heat-sensitive phenotype. bZIP28 has a similar domain structure to the mammalian ATF6 protein involved in the unfolded protein response (UPR), and shares a bZIP domain, transmembrane domain, and a canonical S1P cleavage site. The bZIP28 seems to be glycosylated in vivo. bZIP28 does not appear to be transcriptionally up-regulated by UPR-inducing tunicamycin (TM) treatment. But, the expression level of three UPR-related genes is reduced in TM-treated zip28 mutants relative to wild type seedlings. And several UPR genes are transcriptionally upregulated when an N-terminal portion of the bZIP28 protein is expressed using the 35S promoter. A myc:bZIP28 fusion protein appears to be cleaved, likely at a canonical S2 cleavage site, following a TM treatment or a DTT stress-inducing treatment, but not a salt treatment. A portion of the mGFP:bZIP28 protein present in root cells appears to translocate from the cytoplasm and ER to the nucleus following TM treatment.

Click gene/probe ID to show a list of genes that are homologous to the gene.

Paralogous genes

HFEvBSGene IDRepr. IDGene NameFunctional DescriptionO.I.C.G.S.X.Other DB
0.081e-1275At3g56660824833BZIP49 (BASIC REGION/LEUCINE ZIPPER MOTIF PROTEIN 49)F:transcription factor activity, DNA binding;P:regulation of transcription, DNA-dependent;C:nucleus;MPFOO.I.C.G.S.X.
0.063e-757At2g40950818694BZIP17bZIP17 appears to regulate transcription as part of a salt and osmotic stress response. zip17 mutants show enhanced inhibition of primary root elongation in response to NaCl. Several salt-responsive genes, such as ATHB-7 show a reduced transcriptional response to a salt treatment in zip17 mutant seedlings. myc:bZIP17 undergoes proteolytic processing in salt-treated wild type seedlings, but not in s1p-3 (subtilase) mutants and there is also evidence for S1P-mediated cleavage of bZIP17 in vitro. In addition, an mGFP:bZIP17 protein moves from the ER to the nucleus following salt treatment.O.I.C.G.S.X.
0.014e-344At3g28920822527AtHB34 (ARABIDOPSIS THALIANA HOMEOBOX PROTEIN 34)F:transcription factor activity, DNA binding;P:regulation of transcription;C:unknown;PMFOBVO.I.C.G.S.X.
0.017e-240At5g17460831612unknown proteinF:molecular_function unknown;P:response to salt stress;C:mitochondrion;OMFPBVO.I.C.G.S.X.
0.017e-240At2g29750817525UGT71C1 (UDP-GLUCOSYL TRANSFERASE 71C1)F:quercetin 3'-O-glucosyltransferase activity, quercetin 7-O-glucosyltransferase activity, UDP-glycosyltransferase activity, transferase activity, transferring glycosyl groups;P:metabolic process;C:cellular_component unknown;PMBOVFO.I.C.G.S.X.
0.017e-240At1g612152745841BRD4 (BROMODOMAIN 4)Bromodomain protein with a DNA binding motifO.I.C.G.S.X.
0.013e-138At5g04960830378pectinesterase family proteinF:enzyme inhibitor activity, pectinesterase activity;P:cell wall modification;C:cell wall, plant-type cell wall;PBFMOO.I.C.G.S.X.
0.013e-138At5g61850836307LFY (LEAFY)Encodes transcriptional regulator that promotes the transition to flowering.Involved in floral meristem development. LFY is involved in the regulation of AP3 expression, and appears to bring the F-box protein UFO to the AP3 promoter.O.I.C.G.S.X.
0.013e-138At4g33400829477dem protein-related / defective embryo and meristems protein-relatedF:molecular_function unknown;P:N-terminal protein myristoylation;C:cytosol, nucleus, plasma membrane;FOPMO.I.C.G.S.X.

Orthologous genes

HFEvBSGene IDOrganismRepr. IDGene NameFunctional DescriptionEvAGI codeArabidopsis gene nameO.I.C.G.S.X.Other DB
0.071e-346GmaAffx.3847.2.S1_atGlycine maxBG044893transcription factor bZIP37-4e-11At2g40950BZIP17O.I.C.G.S.X.
0.038e-342Contig8702_atHordeum vulgareContig8702--5e-5At3g56660BZIP49 (BASIC REGION/LEUCINE ZIPPER MOTIF PROTEIN 49)O.I.C.G.S.X.
0.015e-138OsAffx.29870.1.S1_atOryza sativa---0O.I.C.G.S.X.
0.041e-1069Ptp.3328.1.S1_s_atPopulus trichocarpaCV264792hypothetical protein-1e-7At2g40950BZIP17O.I.C.G.S.X.
0.014e+034Ta.8680.1.A1_atTriticum aestivumBQ162217--4e+0Atcg00050-O.I.C.G.S.X.
0.022e-5501621049_s_atVitis viniferaCB349654--1e-11At3g56660BZIP49 (BASIC REGION/LEUCINE ZIPPER MOTIF PROTEIN 49)O.I.C.G.S.X.
0.012e+034ZmAffx.259.1.S1_s_atZea maysAI668215Glycine-rich protein-9e-1At5g40970unknown proteinO.I.C.G.S.X.

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