Homology analysis

Gene ID At2g44110
Gene name MLO15 (MILDEW RESISTANCE LOCUS O 15)
Functional description A member of a large family of seven-transmembrane domain proteins specific to plants, homologs of the barley mildew resistance locus o (MLO) protein. The Arabidopsis genome contains 15 genes encoding MLO proteins, with localization in plasma membrane. Phylogenetic analysis revealed four clades of closely-related AtMLO genes. ATMLO15 belongs to the clade II, with ATMLO13 and ATMLO15. The gene is expressed during early seedling growth, in root tips and flower (papillae, anthers and pollen grains), as shown by GUS activity patterns. The expression of several phylogenetically closely-related AtMLO genes showed similar or overlapping tissue specificity and analogous responsiveness to external stimuli, suggesting functional redundancy, co-function, or antagonistic function(s).

Click gene/probe ID to show a list of genes that are homologous to the gene.

Paralogous genes

HFEvBSGene IDRepr. IDGene NameFunctional DescriptionO.I.C.G.S.X.Other DB
0.048e-446At4g02600828229MLO1A member of a large family of seven-transmembrane domain proteins specific to plants, homologs of the barley mildew resistance locus o (MLO) protein. The Arabidopsis genome contains 15 genes encoding MLO proteins, with localization in plasma membrane. Phylogenetic analysis revealed four clades of closely-related AtMLO genes. ATMLO1 belongs to the clade II, with ATMLO13 and ATMLO15. The gene is expressed during early seedling growth, in root and cotyledon vascular system, in pollen and in papillae, as shown by GUS activity patterns. The expression of several phylogenetically closely-related AtMLO genes showed similar or overlapping tissue specificity and analogous responsiveness to external stimuli, suggesting functional redundancy, co-function, or antagonistic function(s).O.I.C.G.S.X.
0.015e-240At2g17480816254MLO8 (MILDEW RESISTANCE LOCUS O 8)A member of a large family of seven-transmembrane domain proteins specific to plants, homologs of the barley mildew resistance locus o (MLO) protein. The Arabidopsis genome contains 15 genes encoding MLO proteins, with localization in plasma membrane. Phylogenetic analysis revealed four clades of closely-related AtMLO genes. ATMLO8 belongs to the clade III, with AtMLO5, AtMLO7, AtMLO9, and AtMLO10. The gene is expressed during seedling growth, in cotyledons and hypocotyl, and in fruit abscission zone, as shown by GUS activity patterns. The expression of several phylogenetically closely-related AtMLO genes showed similar or overlapping tissue specificity and analogous responsiveness to external stimuli, suggesting functional redundancy, co-function, or antagonistic function(s).O.I.C.G.S.X.
0.025e-240At1g26700839211MLO14 (MILDEW RESISTANCE LOCUS O 14)A member of a large family of seven-transmembrane domain proteins specific to plants, homologs of the barley mildew resistance locus o (MLO) protein. The Arabidopsis genome contains 15 genes encoding MLO proteins, with localization in plasma membrane. Phylogenetic analysis revealed four clades of closely-related AtMLO genes. ATMLO14 belongs to the clade I, with AtMLO4 and AtMLO11. The gene is expressed during early seedling growth, in developing primary root, and particularly in root tips of 10-day old seedlings; it was not expressed in leaves or flowers, as shown by GUS activity patterns. The expression of several phylogenetically closely-related AtMLO genes showed similar or overlapping tissue specificity and analogous responsiveness to external stimuli, suggesting functional redundancy, co-function, or antagonistic function(s).O.I.C.G.S.X.
0.012e-138At4g02070828147MSH6 (MUTS HOMOLOG 6)encodes a DNA mismatch repair homolog of human MutS gene, MSH6. There are four MutS genes in Arabidopsis, MSH2, MSH3, MSH6, and MSH7, which all act as heterodimers and bind to 51-mer duplexes. MSH2*MSH6 bound the (+T) substrate strongly, (T/G) well, and (+AAG) no better than it did a (T/A) homoduplex.O.I.C.G.S.X.
0.037e-136At5g53760835457MLO11 (MILDEW RESISTANCE LOCUS O 11)A member of a large family of seven-transmembrane domain proteins specific to plants, homologs of the barley mildew resistance locus o (MLO) protein. The Arabidopsis genome contains 15 genes encoding MLO proteins, with localization in plasma membrane. Phylogenetic analysis revealed four clades of closely-related AtMLO genes. ATMLO11 belongs to the clade I, with AtMLO4 and AtMLO14. The gene is expressed during early seedling growth (in primary root), in root tips and lateral root primordia, and in very young leaves, and in flowers and fruit abscission zone, as shown by GUS activity patterns. The expression of several phylogenetically closely-related AtMLO genes showed similar or overlapping tissue specificity and analogous responsiveness to external stimuli, suggesting functional redundancy, co-function, or antagonistic function(s).O.I.C.G.S.X.
0.017e-136At4g38890830044dihydrouridine synthase family proteinF:tRNA dihydrouridine synthase activity, FAD binding, catalytic activity;P:oxidation reduction, tRNA processing, metabolic process;C:vacuole;BOMFPAO.I.C.G.S.X.

Orthologous genes

HFEvBSGene IDOrganismRepr. IDGene NameFunctional DescriptionEvAGI codeArabidopsis gene nameO.I.C.G.S.X.Other DB
0.104e-654GmaAffx.25834.1.S1_atGlycine maxBE020055--1e-34At4g02600MLO1O.I.C.G.S.X.
0.041e+034Contig17827_atHordeum vulgareContig17827--2e+0At2g44110MLO15 (MILDEW RESISTANCE LOCUS O 15)O.I.C.G.S.X.
0.021e-450Os02g0562600Oryza sativaAK121163.1-Mlo-related protein family protein1e-4At4g02600MLO1O.I.C.G.S.X.
0.097e-859PtpAffx.217531.1.S1_atPopulus trichocarpapmrna32831hypothetical protein-6e-14At4g02600MLO1O.I.C.G.S.X.
0.062e-138TaAffx.65252.1.A1_atTriticum aestivumBJ254844--7e-2At2g44110MLO15 (MILDEW RESISTANCE LOCUS O 15)O.I.C.G.S.X.
0.053e-13751619391_atVitis viniferaCD797528mildew resistance locus o 15-3e-13At2g44110MLO15 (MILDEW RESISTANCE LOCUS O 15)O.I.C.G.S.X.
0.056e-961Zm.684.1.S1_atZea maysAY029319.1barley mlo defense gene homolog8-6e-8At4g24250MLO13 (MILDEW RESISTANCE LOCUS O 13)O.I.C.G.S.X.



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