Homology analysis

Gene ID At2g07050
Gene name CAS1 (cycloartenol synthase 1)
Functional description Involved in the biosynthesis of brassinosteroids. Catalyzes the reaction from epoxysqualene to cycloartenol.

Click gene/probe ID to show a list of genes that are homologous to the gene.

Paralogous genes

HFEvBSGene IDRepr. IDGene NameFunctional DescriptionO.I.C.G.S.X.Other DB
0.048e-859At4g15370827203BARS1 (BARUOL SYNTHASE 1)Encodes an oxidosqualene cyclase that primarily produces the tetracyclic triterpene baruol in vitro and when expressed in yeast. It can also make 22 other minor triterpenoid products with varying numbers of rings.O.I.C.G.S.X.
0.012e-552At5g48010834852THAS1 (THALIANOL SYNTHASE 1)Encodes an oxidosqualene cyclase involved in the biosynthesis of thalianol, a tricyclic triterpenoid of unknown function. Overexpression of THAS leads to dwarfing in the aerial tissues of Arabidopsis plants, but increases their root length. THAS is part of a small operon-like cluster of genes (with At5g48000 (THAH) and At5g47990 (THAD)) involved in thalianol metabolism.O.I.C.G.S.X.
0.032e-552At1g78500844186pentacyclic triterpene synthase, putativeEncodes a protein with pentacyclic triterpene synthase activity. In addition to the compounds lupeol, α-amyrin and bauerenol, this enzyme was also shown to produce two seco-triterpenes: α- and β-seco-amyrin.O.I.C.G.S.X.
0.037e-550At1g78960844236ATLUP2Encodes a multifunctional 2-3-oxidosqualene (OS)-triterpene cyclase that can cyclize OS into lupeol, alpha- and beta-amyrin.O.I.C.G.S.X.
0.015e-344At1g66960843014lupeol synthase, putative / 2,3-oxidosqualene-triterpenoid cyclase, putativeF:lupeol synthase activity;P:pentacyclic triterpenoid biosynthetic process;C:unknown;BPOFMO.I.C.G.S.X.
0.077e-240At3g45130823649LAS1F:lanosterol synthase activity;P:pentacyclic triterpenoid biosynthetic process;C:cellular_component unknown;BPOFMAO.I.C.G.S.X.
0.047e-240At1g78970844237LUP1 (LUPEOL SYNTHASE 1)Lupeol synthase. Converts oxidosqualene to multiple triterpene alcohols and a triterpene diols. This conversion proceeds through the formation of a 17β-dammarenyl cation.O.I.C.G.S.X.
0.017e-240At1g71100843450RSW10 (RADIAL SWELLING 10)Encodes a ribose 5-phosphate isomerase involved in the formation of uridine used for the synthesis of UDP-sugars. Mutants of this gene are affected in cellulose biosynthesis.O.I.C.G.S.X.

Orthologous genes

HFEvBSGene IDOrganismRepr. IDGene NameFunctional DescriptionEvAGI codeArabidopsis gene nameO.I.C.G.S.X.Other DB
0.454e-35151Gma.6863.1.S1_atGlycine maxBQ628209--2e-35At2g07050CAS1 (cycloartenol synthase 1)O.I.C.G.S.X.
0.261e-29131Contig11705_atHordeum vulgareContig11705--3e-29At2g07050CAS1 (cycloartenol synthase 1)O.I.C.G.S.X.
0.303e-24115Os02g0139700Oryza sativaAK121211.1-Cycloartenol synthase (EC 5.4.99.8)2e-24At2g07050CAS1 (cycloartenol synthase 1)O.I.C.G.S.X.
0.203e-20101Ptp.3309.1.S1_atPopulus trichocarpaBU813099hypothetical protein-1e-20At2g07050CAS1 (cycloartenol synthase 1)O.I.C.G.S.X.
0.191e-31139Ta.9982.1.S1_atTriticum aestivumCA599875--9e-32At2g07050CAS1 (cycloartenol synthase 1)O.I.C.G.S.X.
0.315e-401651618177_atVitis viniferaCF511456hypothetical protein LOC100243389-9e-40At2g07050CAS1 (cycloartenol synthase 1)O.I.C.G.S.X.
0.322e-25117Zm.5697.2.S1_atZea maysAI834433--5e-25At2g07050CAS1 (cycloartenol synthase 1)O.I.C.G.S.X.



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