Homology analysis

Gene ID At1g65060
Gene name 4CL3
Functional description encodes an isoform of 4-coumarate:CoA ligase (4CL), which is involved in the last step of the general phenylpropanoid pathway. mRNA levels are not induced in response to wounding or to fungal infection by P. parasitica. mRNA is expressed in flowers, to a lesser degree in mature leaves and siliques and marginally in seedling roots and bolting stems of mature plants. The catalytic efficiency was in the following (descending) order: p-coumaric acid, caffeic acid, ferulic acid, cinnamic acid and 5-OH-ferulic acid. At4CL3 was unable to use sinapic acid as substrate.

Click gene/probe ID to show a list of genes that are homologous to the gene.

Paralogous genes

HFEvBSGene IDRepr. IDGene NameFunctional DescriptionO.I.C.G.S.X.Other DB
0.154e-1583At1g516808415934CL1 (4-COUMARATE:COA LIGASE 1)encodes an isoform of 4-coumarate:CoA ligase (4CL), which is involved in the last step of the general phenylpropanoid pathway. In addition to 4-coumarate, it also converts ferulate. The catalytic efficiency was in the following (descending) order: p-coumaric acid, ferulic acid, caffeic acid and 5-OH-ferulic acid. At4CL1 was unable to use sinapic acid as substrate.O.I.C.G.S.X.
0.082e-1481At3g212408216784CL2 (4-COUMARATE:COA LIGASE 2)encodes an isoform of 4-coumarate:CoA ligase (4CL), which is involved in the last step of the general phenylpropanoid pathway. The catalytic efficiency was in the following (descending) order: p-coumaric acid, caffeic acid, ferulic acid, 5-OH-ferulic acid and cinnamic acid. At4CL2 was unable to use sinapic acid as substrate.O.I.C.G.S.X.
0.142e-1377At3g212308216774CL5 (4-coumarate:CoA ligase 5)The gene encodes a 4-coumarate coenzyme A ligase being able to use sinapate as substrate. The catalytic efficiency was in the following (descending) order: p-coumaric acid, caffeic acid, 5-OH-ferulic acid, ferulic acid and sinapic acid. At4CL5 was unable to use cinnamic acid as substrate. Knockout of At4CL5 (4cl5) revealed no effect on syringyl lignin content indicating that the activity observed does probably not occur in vivo.O.I.C.G.S.X.
0.041e-552At1g62940842596ACOS5 (ACYL-COA SYNTHETASE 5)encodes an acyl-CoA synthetase, has in vitro activity towards medium- to long-chain fatty acids and their hydroxylated derivatives. Expressed in the tapetum. Involved in pollen wall exine formation. Null mutants were devoid of pollen grains at anther maturity and were completely male sterile.O.I.C.G.S.X.
0.032e-448At4g051608258644-coumarate--CoA ligase, putative / 4-coumaroyl-CoA synthase, putativeEncodes a peroxisomal protein involved in the activation of fatty acids through esterification with CoA. At4g05160 preferentially activates fatty acids with medium chain length (C6:0 and C7:0) as well as even-numbered long-chain fatty acids (C14:0, C16:0 and C18:0). At4g05160 was also able to catalyze the conversion of OPC-6:0 to its CoA ester and is therefore thought to be involved in the peroxisomal β-oxidation steps of jasmonic acid biosynthesis.O.I.C.G.S.X.
0.015e-240At1g62760842574invertase/pectin methylesterase inhibitor family proteinF:enzyme inhibitor activity, pectinesterase inhibitor activity, pectinesterase activity;P:unknown;C:unknown;MOFBPVAO.I.C.G.S.X.

Orthologous genes

HFEvBSGene IDOrganismRepr. IDGene NameFunctional DescriptionEvAGI codeArabidopsis gene nameO.I.C.G.S.X.Other DB
0.122e-1481Gma.8449.1.S1_atGlycine maxAF002258.14-coumarate:CoA ligase isoenzyme 3-2e-14At1g650604CL3O.I.C.G.S.X.
0.077e-342Contig4677_atHordeum vulgareContig4677--8e-3At1g650604CL3O.I.C.G.S.X.
0.071e-450Os02g0697400Oryza sativaAK105636.1-4-coumarate--CoA ligase 2 (EC 6.2.1.12) (4CL 2)(4-coumaroyl-CoA synthase 2)8e-5At1g650604CL3O.I.C.G.S.X.
0.241e-21105PtpAffx.12056.3.S1_a_atPopulus trichocarpaCV2594944-Coumarate:CoA ligase-5e-22At1g650604CL3O.I.C.G.S.X.
0.042e-448TaAffx.30205.2.S1_s_atTriticum aestivumCA627137--1e-4At3g212404CL2 (4-COUMARATE:COA LIGASE 2)O.I.C.G.S.X.
0.123e-13751619320_atVitis viniferaCB974305--7e-13At1g650604CL3O.I.C.G.S.X.
0.044e-136Zm.11845.1.A1_atZea maysCO532590--3e-1At1g650604CL3O.I.C.G.S.X.



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