Homology analysis

Gene ID At1g61560
Gene name MLO6 (MILDEW RESISTANCE LOCUS O 6)
Functional description A member of a large family of seven-transmembrane domain proteins specific to plants, homologs of the barley mildew resistance locus o (MLO) protein. The Arabidopsis genome contains 15 genes encoding MLO proteins, with localization in plasma membrane. Phylogenetic analysis revealed four clades of closely-related AtMLO genes. ATMLO6 belongs to the clade IV, with AtMLO2, AtMLO3 and AtMLO12. The gene is expressed during early seedling growth, in roots and lateral root primordia, in flower and fruit abscission zone, in vascular system of cotyledons, young leaves and petals, in mature rosette leaves, in anthers, as shown by GUS activity patterns. The expression of several phylogenetically closely-related AtMLO genes showed similar or overlapping tissue specificity and analogous responsiveness to external stimuli, suggesting functional redundancy, co-function, or antagonistic function(s).

Click gene/probe ID to show a list of genes that are homologous to the gene.

Paralogous genes

HFEvBSGene IDRepr. IDGene NameFunctional DescriptionO.I.C.G.S.X.Other DB
0.592e-137490At1g11310837673MLO2 (MILDEW RESISTANCE LOCUS O 2)A member of a large family of seven-transmembrane domain proteins specific to plants, homologs of the barley mildew resistance locus o (MLO) protein. The Arabidopsis genome contains 15 genes encoding MLO proteins, with localization in plasma membrane. Phylogenetic analysis revealed four clades of closely-related AtMLO genes. ATMLO2 belongs to the clade IV, with AtMLO3, AtMLO6 and AtMLO12. The gene is expressed during early seedling growth, in roots, in vascular system of cotyledons and young leaves,and in fruit abscission zone; it was not expressed in anthers and pollen, as shown by GUS activity patterns. The expression of several phylogenetically closely-related AtMLO genes showed similar or overlapping tissue specificity and analogous responsiveness to external stimuli, suggesting functional redundancy, co-function, or antagonistic function(s). mlo resistance in A. thaliana does not involve the signaling molecules ethylene, jasmonic acid or salicylic acid, but requires a syntaxin, glycosyl hydrolase and ABC transporter.O.I.C.G.S.X.
0.313e-1997At2g39200818505MLO12 (MILDEW RESISTANCE LOCUS O 12)A member of a large family of seven-transmembrane domain proteins specific to plants, homologs of the barley mildew resistance locus o (MLO) protein. The Arabidopsis genome contains 15 genes encoding MLO proteins, with localization in plasma membrane. Phylogenetic analysis revealed four clades of closely-related AtMLO genes. ATMLO6 belongs to the clade IV, with AtMLO2, AtMLO3 and AtMLO12. The gene is expressed during early seedling growth, in root tips and cotyledon vascular system, in floral organs (anthers and stigma), and in fruit abscission zone, as shown by GUS activity patterns. The expression of several phylogenetically closely-related AtMLO genes showed similar or overlapping tissue specificity and analogous responsiveness to external stimuli, suggesting functional redundancy, co-function, or antagonistic function(s).O.I.C.G.S.X.
0.031e-346At5g65970836727MLO10 (MILDEW RESISTANCE LOCUS O 10)A member of a large family of seven-transmembrane domain proteins specific to plants, homologs of the barley mildew resistance locus o (MLO) protein. The Arabidopsis genome contains 15 genes encoding MLO proteins, with localization in plasma membrane. Phylogenetic analysis revealed four clades of closely-related AtMLO genes. ATMLO10 belongs to the clade III, with AtMLO5, AtMLO7, AtMLO8, and AtMLO9. The gene is expressed in root and cotyledon vascular system, in root-shoot junction and lateral root primordia and in developing siliques, as shown by GUS activity patterns. The expression of several phylogenetically closely-related AtMLO genes showed similar or overlapping tissue specificity and analogous responsiveness to external stimuli, suggesting functional redundancy, co-function, or antagonistic function(sO.I.C.G.S.X.
0.021e-242At4g004676240657-F:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;POO.I.C.G.S.X.
0.011e-242At1g70630843400-F:molecular_function unknown;P:biological_process unknown;C:endoplasmic reticulum;POO.I.C.G.S.X.
0.016e-240At5g42940834306zinc finger (C3HC4-type RING finger) family proteinF:protein binding, zinc ion binding;P:unknown;C:unknown;PMOFVBAO.I.C.G.S.X.
0.036e-240At4g24250828526MLO13 (MILDEW RESISTANCE LOCUS O 13)A member of a large family of seven-transmembrane domain proteins specific to plants, homologs of the barley mildew resistance locus o (MLO) protein. The Arabidopsis genome contains 15 genes encoding MLO proteins, with localization in plasma membrane. Phylogenetic analysis revealed four clades of closely-related AtMLO genes. ATMLO13 belongs to the clade II, with ATMLO1 and ATMLO15. The gene is expressed during early seedling growth, in root and cotyledon vascular system, in pollen and also in placenta of developing siliques, as shown by GUS activity patterns. The expression of several phylogenetically closely-related AtMLO genes showed similar or overlapping tissue specificity and analogous responsiveness to external stimuli, suggesting functional redundancy, co-function, or antagonistic function(s).O.I.C.G.S.X.
0.026e-240At4g22380828333ribosomal protein L7Ae/L30e/S12e/Gadd45 family proteinF:RNA binding;P:ribosome biogenesis;C:nucleolus;MOAFPBO.I.C.G.S.X.

Orthologous genes

HFEvBSGene IDOrganismRepr. IDGene NameFunctional DescriptionEvAGI codeArabidopsis gene nameO.I.C.G.S.X.Other DB
0.055e-344GmaAffx.83232.1.S1_atGlycine maxBE023128--1e-19At2g17430MLO7 (MILDEW RESISTANCE LOCUS O 7)O.I.C.G.S.X.
0.022e+034Contig6351_atHordeum vulgareContig6351--3e-4At1g42560MLO9 (MILDEW RESISTANCE LOCUS O 9)O.I.C.G.S.X.
0.022e+036Os07g0688150Oryza sativaNM_185511.1--7e-1At1g18040CDKD1O.I.C.G.S.X.
0.101e-965PtpAffx.205053.1.S1_atPopulus trichocarpapmrna10012hypothetical protein-4e-9At2g39200MLO12 (MILDEW RESISTANCE LOCUS O 12)O.I.C.G.S.X.
0.034e+034Ta.280.2.S1_x_atTriticum aestivumBG904890MLo1 protein /// seven transmembrane-spanning protein-2e-4At1g42560MLO9 (MILDEW RESISTANCE LOCUS O 9)O.I.C.G.S.X.
0.022e-2401609415_atVitis viniferaCA817605hypothetical protein LOC100254309-2e-62At2g01600epsin N-terminal homology (ENTH) domain-containing proteinO.I.C.G.S.X.
0.022e+034Zm.18022.1.S1_atZea maysAY029312.2barley mlo defense gene homolog1-3e-1At2g44110MLO15 (MILDEW RESISTANCE LOCUS O 15)O.I.C.G.S.X.



Back to the CoP portal site

Back to the KAGIANA project homepage