Homology analysis

Gene ID At1g29690
Gene name CAD1 (constitutively activated cell death 1)
Functional description Encodes a protein containing a domain with significant homology to the MACPF (membrane attack complex and perforin) domain of complements and perforin proteins that are involved in innate immunity in animals. Transgenic cad1-1 mutant plants show lesions seen in the hypersensitive response, as well as a spontaneous activation of expression of pathogenesis-related genes and leading to a 32-fold increase in salicylic acid (SA). CAD1 is postulated to act as a negative regulator controlling SA-mediated pathway of programmed cell death in plant immunity.

Click gene/probe ID to show a list of genes that are homologous to the gene.

Paralogous genes

HFEvBSGene IDRepr. IDGene NameFunctional DescriptionO.I.C.G.S.X.Other DB
0.011e-242At3g54080824575sugar bindingF:sugar binding;P:biological_process unknown;C:endomembrane system;PBO.I.C.G.S.X.
0.012e-138At4g34100829556protein binding / zinc ion bindingF:protein binding, zinc ion binding;P:unknown;C:chloroplast;MPOFVO.I.C.G.S.X.
0.018e-136At2g41410818739calmodulin, putativeF:calcium ion binding;P:unknown;C:plasma membrane;MPFOBO.I.C.G.S.X.
0.018e-136At1g04090839298unknown proteinF:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;PFBMOO.I.C.G.S.X.
0.018e-136At1g49190841342ARR19 (ARABIDOPSIS RESPONSE REGULATOR 19)member of Response Regulator: B- TypeO.I.C.G.S.X.
0.018e-136At1g18350838416ATMKK7MAP kinase kinase7. Member of plant mitogen-activated protein kinase kinase group D. Negative regulator of polar auxin transport. Overexpression leads to activation of basal and systemic acquired resistance.O.I.C.G.S.X.
0.018e-136At1g56145842067leucine-rich repeat family protein / protein kinase family proteinF:protein binding, protein serine/threonine kinase activity, protein kinase activity, ATP binding;P:protein amino acid phosphorylation;C:plasma membrane;PMOBFVAO.I.C.G.S.X.

Orthologous genes

HFEvBSGene IDOrganismRepr. IDGene NameFunctional DescriptionEvAGI codeArabidopsis gene nameO.I.C.G.S.X.Other DB
0.266e-1893Gma.4262.1.S1_atGlycine maxCD406832--4e-18At1g29690CAD1 (constitutively activated cell death 1)O.I.C.G.S.X.
0.127e-961Contig13528_atHordeum vulgareContig13528--9e-9At1g29690CAD1 (constitutively activated cell death 1)O.I.C.G.S.X.
0.024e-448OsAffx.21623.1.S1_atOryza sativa---0O.I.C.G.S.X.
0.253e-1377PtpAffx.55857.1.A1_atPopulus trichocarpaCV244535hypothetical protein-2e-13At1g29690CAD1 (constitutively activated cell death 1)O.I.C.G.S.X.
0.096e-1169Ta.12913.1.S1_atTriticum aestivumCA741662--7e-11At1g29690CAD1 (constitutively activated cell death 1)O.I.C.G.S.X.
0.021e+0341610917_atVitis viniferaCD715674--2e-2At3g14670unknown proteinO.I.C.G.S.X.
0.042e-859Zm.3750.1.A1_atZea maysCO517698MAC/Perforin domain containing protein-3e-8At1g29690CAD1 (constitutively activated cell death 1)O.I.C.G.S.X.

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