Homology analysis

Gene ID At1g28380
Gene name NSL1 (necrotic spotted lesions 1)
Functional description This gene is predicted to encode a protein involved in negatively regulating salicylic acid-related defense responses and cell death programs. nsl1 mutants develop necrotic lesions spontaneously and show other features of a defense response, such as higher levels of SA and disease resistance-related transcripts, in the absence of a biotic stimulus. The NSL1 protein is predicted to have a MACPF domain, found in proteins that form a transmembrane pore in mammalian immune responses. NSL1 transcript levels do not appear to change in response to biotic stresses, but are elevated by cycloheximide in seedlings, and by sodium chloride in roots.

Click gene/probe ID to show a list of genes that are homologous to the gene.

Paralogous genes

HFEvBSGene IDRepr. IDGene NameFunctional DescriptionO.I.C.G.S.X.Other DB
0.022e-138At4g20380827786zinc finger protein (LSD1)LSD1 monitors a superoxide-dependent signal and negatively regulates a plant cell death pathway. contains zinc-finger motifs. LSD1 negatively regulates a basal defense pathway that can act upstream or independently of both NIM1/NPR1 function and SA accumulation following avirulent or virulent pathogen challengeO.I.C.G.S.X.
0.019e-136At5g15890831446unknown proteinF:unknown;P:biological_process unknown;C:unknown;PMFOVBAO.I.C.G.S.X.

Orthologous genes

HFEvBSGene IDOrganismRepr. IDGene NameFunctional DescriptionEvAGI codeArabidopsis gene nameO.I.C.G.S.X.Other DB
0.028e-240GmaAffx.91343.1.S1_atGlycine maxCF807068--3e-4At4g24290-O.I.C.G.S.X.
0.012e+034Contig1221_x_atHordeum vulgareContig1221--5e+0At5g19140AILP1O.I.C.G.S.X.
0.045e-138Os05g0557400Oryza sativaAK069566.1-Membrane attack complexcomponent/perforin/complement C9 family protein3e-1At1g28380NSL1 (necrotic spotted lesions 1)O.I.C.G.S.X.
0.186e-1273PtpAffx.203874.1.S1_atPopulus trichocarpapmrna7654hypothetical protein-4e-12At1g28380NSL1 (necrotic spotted lesions 1)O.I.C.G.S.X.
0.021e+036TaAffx.57600.1.S1_atTriticum aestivumCA626678--2e-2At4g12440adenine phosphoribosyltransferase, putativeO.I.C.G.S.X.
0.021e+0341621779_s_atVitis viniferaBQ794980hypothetical protein LOC100244148-6e-40At3g52560UEV1D-4 (UBIQUITIN E2 VARIANT 1D-4)O.I.C.G.S.X.
0.012e+034ZmAffx.485.1.S1_atZea maysAI691349--8e-1Atmg00140-O.I.C.G.S.X.

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