Homology analysis

Gene ID At1g16420
Gene name MC8 (METACASPASE 8)
Functional description Encodes a metacaspase (cysteine-type endopeptidase) that is involved in promoting programmed cell death in response to hydrogen peroxide (H2O2), UV light, and methyl viologen (MV). Transcript levels rise in response to UV-C, H2O2, and MV. In vitro assays demonstrate that this enzyme has a preference for cleaving after an arginine residue, and it has a pH optimum of 8.0.

Click gene/probe ID to show a list of genes that are homologous to the gene.

Paralogous genes

HFEvBSGene IDRepr. IDGene NameFunctional DescriptionO.I.C.G.S.X.Other DB
0.084e-859At1g79310844269AtMC7 (metacaspase 7)F:cysteine-type endopeptidase activity;P:proteolysis;C:cellular_component unknown;BFOPAO.I.C.G.S.X.
0.136e-756At1g79330844271ATMC5 (ARABIDOPSIS THALIANA METACASPASE 5)Metacaspase AtMCPb2/AMC6. Caspase family protein. Arginine/lysine-specific cysteine protease activity. Induces apoptosis in yeast. Contains Pfam domain, PF00656: ICE-like protease (caspase) p20 domain.O.I.C.G.S.X.
0.039e-342At5g04200830299AtMC9 (metacaspase 9)F:cysteine-type peptidase activity;P:proteolysis;C:apoplast;FPBOAO.I.C.G.S.X.
0.024e-240At1g14000837960VIK (VH1-INTERACTING KINASE)Encodes a protein with similarity to members of the C1 subgroup of MAP kinase kinase kinases. Interacts physically with the receptor kinase BRL2/VH1 and appears to be involved in auxin and brassinosteriod signaling.O.I.C.G.S.X.
0.091e-138At1g79340844272AtMC4 (metacaspase 4)F:cysteine-type peptidase activity;P:proteolysis;C:plasma membrane;BOFPAMO.I.C.G.S.X.
0.016e-136At5g66760836809SDH1-1One of two genes in Arabidopsis that encode a flavoprotein subunit of the mitochondrial succinate dehydrogenase complex.O.I.C.G.S.X.
0.046e-136At1g79320844270AtMC6 (metacaspase 6)F:cysteine-type endopeptidase activity;P:proteolysis;C:cellular_component unknown;BOFPAO.I.C.G.S.X.
0.026e-136At1g36510840559-F:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;PO.I.C.G.S.X.
0.012e+034At5g24280832495-F:unknown;P:unknown;C:unknown;PMOBFO.I.C.G.S.X.

Orthologous genes

HFEvBSGene IDOrganismRepr. IDGene NameFunctional DescriptionEvAGI codeArabidopsis gene nameO.I.C.G.S.X.Other DB
0.033e+034GmaAffx.90218.1.S1_atGlycine maxCF805943SGT1-2-7e-12At4g11260SGT1BO.I.C.G.S.X.
0.024e+032Contig15773_atHordeum vulgareContig15773--4e+0At4g05240ubiquitin family proteinO.I.C.G.S.X.
0.021e+036Os11g0632100Oryza sativa9639.m03805--5e+0At5g21110unknown proteinO.I.C.G.S.X.
0.038e-136PtpAffx.207822.1.S1_atPopulus trichocarpapmrna15542hypothetical protein-2e-32At1g79320AtMC6 (metacaspase 6)O.I.C.G.S.X.
0.029e+032TaAffx.106876.1.S1_atTriticum aestivumCA709831--3e-1At2g44150ASHH3 (HISTONE-LYSINE N-METHYLTRANSFERASE ASHH3)O.I.C.G.S.X.
0.034e-2381608947_atVitis viniferaCF609927hypothetical protein LOC100244812-7e-8At5g04200AtMC9 (metacaspase 9)O.I.C.G.S.X.
0.022e+130ZmAffx.755.1.S1_atZea maysAI745946--1e-27Atcg00800-O.I.C.G.S.X.



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