Co-expression analysis

Gene ID Os04g0461300
Gene name
Homology with ArabidopsisSimilar to At3g57230: AGL16 (AGAMOUS-LIKE 16) (HF=3e-7)
Module size 6 genes
NF 0.23
%ile 21.3

Co-expressed genes

Click gene/probe ID to show a list of genes that are co-expressed with the gene.

VF %ile CC Gene ID Repr. ID Gene name Func.EvAGI codeArabidopsis gene name O.I. H.G. S.X. Other DB
0.8395.80.97Os04g04613009632.m03661-MADS-box transcription factor MADS23e-7At3g57230AGL16 (AGAMOUS-LIKE 16)O.I.H.G.S.X.
0.2219.40.98Os09g01074009637.m00042--2e+0At3g03460unknown proteinO.I.H.G.S.X.
0.2219.40.98Os02g01962009630.m00943--5e-1At4g25490CBF1 (C-REPEAT/DRE BINDING FACTOR 1)O.I.H.G.S.X. finger (C3HC4-type RING finger) family proteinO.I.H.G.S.X. proteinO.I.H.G.S.X.

Click More genes

Specific experiments for the module

Std2 GX %ile GSM ID Assay name GSE ID Experiment title Link to GEO
62.499.9GSM422672DroughtGSE16865Heterologous microarrays for the study of drought stress in MusaLink to GEO
22.699.3GSM377078Genomic DNA - 45 day old leaf sample - mutant g6603GSE15071Detection of genomic deletions in rice by genomic DNA hybridization to oligonucleotide microarraysLink to GEO
18.999.0GSM195222Ovary 2, biological rep 2GSE7951Genome-wide gene expression profiling of rice stigmaLink to GEO
17.798.9GSM377070Genomic DNA - 45 day old leaf sample - mutant d1GSE15071Detection of genomic deletions in rice by genomic DNA hybridization to oligonucleotide microarraysLink to GEO
15.898.7GSM377072Genomic DNA - 45 day old leaf sample - mutant d1137GSE15071Detection of genomic deletions in rice by genomic DNA hybridization to oligonucleotide microarraysLink to GEO
15.798.7GSM377077Genomic DNA - 45 day old leaf sample - mutant g6489GSE15071Detection of genomic deletions in rice by genomic DNA hybridization to oligonucleotide microarraysLink to GEO
15.398.7GSM377081Genomic DNA - 45 day old leaf sample - mutant g7534GSE15071Detection of genomic deletions in rice by genomic DNA hybridization to oligonucleotide microarraysLink to GEO
15.298.7GSM195221Ovary 1, biological rep 1GSE7951Genome-wide gene expression profiling of rice stigmaLink to GEO
14.998.6GSM377075Genomic DNA - 45 day old leaf sample - mutant g650GSE15071Detection of genomic deletions in rice by genomic DNA hybridization to oligonucleotide microarraysLink to GEO
14.898.6GSM377084Genomic DNA - 45 day old leaf sample - mutant f1856GSE15071Detection of genomic deletions in rice by genomic DNA hybridization to oligonucleotide microarraysLink to GEO

Biological processes inferred to relate to the module

SFGenesGO IDProcess NameLink to AmiGO

Inter-species module comparison

A co-expression module including the Arabidopsis gene, At3g57230, orthologous to the query gene, Os04g0461300

VF%ileGene IDRepr. IDGene NameFunc.O.I.H.G.S.X.Other DB
1.00100.0At3g57230824890AGL16 (AGAMOUS-LIKE 16)MADS-box transcription factor. Expressed in leaf, root and stem, with higher RNA accumulation in guard cells and trichomes.O.I.H.G.S.X.
0.5267.4At1g34120840311IP5PI (INOSITOL POLYPHOSPHATE 5-PHOSPHATASE I)Encodes an inositol polyphosphate 5-phosphatase that appears to have Type I activity. It can dephosphorylate IP3(inositol(1,4,5)P3) and IP4 (inositol(1,3,4,5)P4), but it does not act on I(1)P, I(1,4)P2, or phosphatidylinositol(4,5)P2.O.I.H.G.S.X.
0.4659.8At5g10790830946UBP22 (UBIQUITIN-SPECIFIC PROTEASE 22)Encodes a ubiquitin-specific protease.O.I.H.G.S.X.
0.4558.3At2g01980814729SOS1 (SALT OVERLY SENSITIVE 1)Encodes a plasma membrane-localized Na+/H+ antiporter SOS1. Functions in the extrusion of toxic Na+ from cells and is essential for plant salt tolerance. Has 12 predicted transmembrane domains in the N-terminal region and a long cytoplasmic tail of approx. 700 aa at the C-terminal side. SOS1 interacts through its predicted cytoplasmic tail with RCD1, a regulator of oxidative-stress responses, suggesting that SOS1 might function in oxidative-stress tolerance.O.I.H.G.S.X.
0.4457.2At1g47310841134unknown proteinF:molecular_function unknown;P:biological_process unknown;C:endomembrane system;PO.I.H.G.S.X.
0.4253.9At5g05700830454ATE1 (ARGININE-TRNA PROTEIN TRANSFERASE 1)Encodes an arginyl-tRNA:protein transferase (ATE1), a component of the N-end rule pathway that targets protein degradation through the identity of the amino-terminal residue of specific protein substrates. Arabidopsis contains two ATE genes: At5g05700/ATE1, At3g11240/ATE2. Another component of the N-end rule pathway is At5g02310/PROTEOLYSIS6 (PRT6). PRT6 and ATE were shown to regulate seed after-ripening, seedling sugar sensitivity, seedling lipid breakdown, and abscisic acid (ABA) sensitivity of germination. Mutants of ATE1 also display delayed leaf senescence.O.I.H.G.S.X.
0.4253.9At1g49710841394FUT12 (FUCOSYLTRANSFERASE 12)Encodes a protein with core α1,3-fucosyltransferase activity.O.I.H.G.S.X.
0.4152.4At5g61580836279PFK4 (PHOSPHOFRUCTOKINASE 4)F:6-phosphofructokinase activity;P:glycolysis;C:6-phosphofructokinase complex, chloroplast;BOMPFAVO.I.H.G.S.X.
0.4152.4At5g43100834326aspartyl protease family proteinF:aspartic-type endopeptidase activity;P:proteolysis;C:endomembrane system;MPFOO.I.H.G.S.X.
0.4050.8At2g04620815004cation efflux family proteinF:cation transmembrane transporter activity, efflux transmembrane transporter activity;P:cation transport;C:membrane;OBMFPAVO.I.H.G.S.X.
0.4050.8At5g52880835365F-box family proteinF:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;MPFOO.I.H.G.S.X.
0.3846.7At1g28320839726DEG15Mutants in this gene are defective in the processing of pre-glyoxysomal malate dehydrogenase (pre-gMDH) to gMDH.O.I.H.G.S.X.
0.3846.7At3g29270822584ubiquitin-protein ligaseF:ubiquitin-protein ligase activity;P:unknown;C:unknown;MPOO.I.H.G.S.X.
0.3846.7At1g68160843144unknown proteinF:unknown;P:biological_process unknown;C:chloroplast;POFO.I.H.G.S.X.
0.3745.0At2g18250816341ATCOAD (4-phosphopantetheine adenylyltransferase)At2g18250 encodes pantetheine-phosphate adenylyltransferase catalyzing the formation of dephospho-CoA from pantetheine 4'-phosphate. The enzyme is involved in coenzyme A biosynthesis.O.I.H.G.S.X.
0.3745.0At3g05250819689zinc finger (C3HC4-type RING finger) family proteinF:protein binding, zinc ion binding;P:unknown;C:unknown;MPVOFO.I.H.G.S.X.
0.3745.0At4g19670827711zinc finger (C3HC4-type RING finger) family proteinF:protein binding, zinc ion binding;P:unknown;C:unknown;MPOFBO.I.H.G.S.X.
0.3745.0At1g72175843549zinc finger (C3HC4-type RING finger) family proteinF:protein binding, zinc ion binding;P:unknown;C:unknown;MOFPBVO.I.H.G.S.X.
0.3643.6At1g69980843335unknown proteinF:unknown;P:unknown;C:endomembrane system;PO.I.H.G.S.X.
0.3643.6At4g03080828097kelch repeat-containing serine/threonine phosphoesterase family proteinF:hydrolase activity, manganese ion binding, protein serine/threonine phosphatase activity, iron ion binding, phosphoprotein phosphatase activity;P:unknown;C:plasma membrane;MOPFBAVO.I.H.G.S.X.
0.3643.6At5g63910836512FCLY (FARNESYLCYSTEINE LYASE)encodes for a farnesylcysteine lyase (EC - prenylcysteine oxidase) involved in a salvage pathway of farnesyl diphosphate.O.I.H.G.S.X.
0.3643.6At3g53090824475UPL7encodes a ubiquitin-protein ligase containing a HECT domain. There are six other HECT-domain UPLs in Arabidopsis.O.I.H.G.S.X.
0.3643.6At3g05210819685ERCC1encodes a homolog of human ERCC1 protein (yeast RAD10), which is a DNA repair endonuclease. Mutants are sensitive to UV-B and gamma radiation (G2 cell cycle phase arrest) and are defective in dark-repair of pyrimidine pyrimidone dimers. This protein incises the 5' end of damaged DNA, similar to ERCC1/RAD10.O.I.H.G.S.X.
0.3541.6At3g59950825165autophagy 4b (APG4b)F:peptidase activity;P:autophagy;C:chloroplast;MOFPO.I.H.G.S.X.
0.3541.6At5g63280836448zinc finger (C2H2 type) family proteinF:zinc ion binding, nucleic acid binding;P:biological_process unknown;C:endomembrane system, intracellular;MPOO.I.H.G.S.X.
0.3541.6At5g25360832608unknown proteinF:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;POO.I.H.G.S.X.
0.3541.6At1g10940837637SNRK2.4 (SNF1-RELATED PROTEIN KINASE 2.4)Encodes a plant protein kinase similar to the calcium/calmodulin-dependent protein kinase subfamily and the SNF1 kinase subfamily (SnRK2) whose activity is activated by ionic (salt) and non-ionic (mannitol) osmotic stress. Kinase activity of its homolog in tobacco is induced by hyperosmotic condition within 1 minute.O.I.H.G.S.X.
0.3439.8At3g12100820384cation efflux family protein / metal tolerance protein, putativeF:cation transmembrane transporter activity, efflux transmembrane transporter activity;P:cation transport, response to nematode;C:membrane;BMFOPAO.I.H.G.S.X.
0.3439.8At3g17880821056ATTDX (TETRATICOPEPTIDE DOMAIN-CONTAINING THIOREDOXIN)Encodes a thioredoxin-like disulfide reductase. The protein interacts with the yeast Hsp70 protein Ssb2 in vitro. This interaction is sensitive to the redox status of the thioredoxin domain of AtTDX.O.I.H.G.S.X.
0.3439.8At5g35560833521DENN (AEX-3) domain-containing proteinF:molecular_function unknown;P:biological_process unknown;C:unknown;MOFPO.I.H.G.S.X.
0.3439.8At5g49950835059embryogenesis-associated protein-relatedF:molecular_function unknown;P:biological_process unknown;C:endomembrane system;BOMFPO.I.H.G.S.X.
0.3439.8At1g35470840440SPla/RYanodine receptor (SPRY) domain-containing proteinF:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;MFOPO.I.H.G.S.X.
0.3439.8At4g13730827007RabGAP/TBC domain-containing proteinF:RAB GTPase activator activity;P:regulation of Rab GTPase activity;C:intracellular, chloroplast;MOFPBO.I.H.G.S.X.
0.3439.8At3g53030824469SRPK4 (Ser/Arg-rich protein kinase 4)Encodes a protein kinase SRPK4 that specifically targets Arabidopsis Ser/Arg-rich (SR) slicing factors involved in RNA metabolism. In vitro kinase assay showed that SRPK4 phosphorylates the SR protein RSp31.O.I.H.G.S.X.
0.3338.1At2g40410818634Ca(2+)-dependent nuclease, putativeF:nuclease activity;P:N-terminal protein myristoylation;C:cellular_component unknown;PO.I.H.G.S.X.
0.3338.1At3g03740821170ATBPM4 (BTB-POZ and MATH domain 4)F:protein binding;P:biological_process unknown;C:unknown;MPOFVO.I.H.G.S.X.
0.3338.1At1g14000837960VIK (VH1-INTERACTING KINASE)Encodes a protein with similarity to members of the C1 subgroup of MAP kinase kinase kinases. Interacts physically with the receptor kinase BRL2/VH1 and appears to be involved in auxin and brassinosteriod signaling.O.I.H.G.S.X.
0.3338.1At1g21380838737VHS domain-containing protein / GAT domain-containing proteinF:protein transporter activity;P:intracellular protein transport, intra-Golgi vesicle-mediated transport;C:Golgi stack, intracellular;MFPOBO.I.H.G.S.X.
0.3338.1At5g64813836603LIP1 (Light Insensitive Period1)The LIP1 gene encodes a small GTPase that influences the light input pathway of the plant circadian network. An MBP:LIP1 fusion protein has GTP hydrolyzing abilities in vitro. In plants, LIP1 seems to play a negative role in regulating circadian period that can be suppressed by light. LIP1 also seems to negatively affect light-pulse-dependent resetting of the clock, especially during the first portion of the subjective evening. LIP1 expression levels are not significantly affected by the circadian clock in seedlings grown under LL conditions. The levels of the YFP:LIP1 protein expressed under the control of the 35S promoter, shows a low amplitude variation, with protein levels peaking near the beginning of subjective night under LL conditions. In hypocotyl epidermal cells of dark and light-grown seedlings, a YFP:LIP1 fusion protein can be seen in the cytoplasm and the nucleus, and does not cluster in nuclear speckles. LIP1 may also be involved in photomorphogenesis.O.I.H.G.S.X.
0.3235.7At4g15475827219F-box family protein (FBL4)F:ubiquitin-protein ligase activity;P:ubiquitin-dependent protein catabolic process;C:unknown;MPOFBVO.I.H.G.S.X.
0.3235.7At1g24350839051-F:unknown;P:biological_process unknown;C:unknown;BOPO.I.H.G.S.X.
0.3235.7At3g15430820782regulator of chromosome condensation (RCC1) family proteinF:Ran GTPase binding;P:biological_process unknown;C:cellular_component unknown;MOPBFAVO.I.H.G.S.X.
0.3235.7At5g55500835643XYLT (ARABIDOPSIS THALIANA BETA-1,2-XYLOSYLTRANSFERASE)Encodes a beta-1,2-xylosyltransferase that is glycosylated at two positions.O.I.H.G.S.X.
0.3133.8At4g31410829268unknown proteinF:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;PBMO.I.H.G.S.X.
0.3133.8At2g36360818209kelch repeat-containing proteinF:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;MOPFBAO.I.H.G.S.X.
0.3133.8At2g41790818778peptidase M16 family protein / insulinase family proteinF:metalloendopeptidase activity, zinc ion binding, catalytic activity, metal ion binding;P:proteolysis;C:cellular_component unknown;BOMFPAVO.I.H.G.S.X.
0.3032.1At3g56840824851FAD-dependent oxidoreductase family proteinF:oxidoreductase activity;P:biological_process unknown;C:cellular_component unknown;BOMFAPVO.I.H.G.S.X.
0.3032.1At4g05000825842VPS28-2F:transporter activity;P:transport;C:ESCRT I complex;MFPOO.I.H.G.S.X.
0.3032.1At3g56740824841ubiquitin-associated (UBA)/TS-N domain-containing proteinF:molecular_function unknown;P:biological_process unknown;C:endomembrane system;FMPOBO.I.H.G.S.X.
0.3032.1At4g27650828876PEL1 (PELOTA)Encodes Arabidopsis homolog of Drosophila pelota protein.O.I.H.G.S.X.
0.3032.1At1g48790841301mov34 family proteinF:molecular_function unknown;P:ubiquitin-dependent protein catabolic process;C:cellular_component unknown;MFPOO.I.H.G.S.X.
0.3032.1At4g30360829159ATCNGC17member of Cyclic nucleotide gated channel familyO.I.H.G.S.X.
0.3032.1At4g27040828812VPS22F:molecular_function unknown;P:vesicle-mediated transport;C:ESCRT II complex;MFOPO.I.H.G.S.X.
0.2930.3At3g04970819657zinc finger (DHHC type) family proteinF:zinc ion binding;P:biological_process unknown;C:endomembrane system;MOFPO.I.H.G.S.X.
0.2930.3At1g77140844050VPS45 (VACUOLAR PROTEIN SORTING 45)A peripheral membrane protein that associates with microsomal membranes, likely to function in the transport of proteins to the vacuole. It is a member of Sec1p protein family. It may be involved in the regulation of vesicle fusion reactions through interaction with t-SNAREs at the Golgi trans face.O.I.H.G.S.X.
0.2930.3At1g71190843459SAG18 (SENESCENCE ASSOCIATED GENE 18)Senescence associated gene (SAG). Expression induced by ozone. Encodes a plant-specific protein of unknown function. Based on a personal communication from David Meinke (08/21/2007), this gene is not allelic to TTN4, even though this has been stated previously in a publication.O.I.H.G.S.X.
0.2830.3At5g18190831937protein kinase family proteinF:protein serine/threonine kinase activity, protein kinase activity, kinase activity, ATP binding;P:protein amino acid phosphorylation;C:cellular_component unknown;MBOPFVAO.I.H.G.S.X.
0.2726.2At1g60430842338ARPC3 (actin-related protein C3)F:structural molecule activity;P:actin filament organization;C:Arp2/3 protein complex;MFOPO.I.H.G.S.X.
0.2726.2At2g17110816215unknown proteinF:unknown;P:N-terminal protein myristoylation;C:cellular_component unknown;PMFBOO.I.H.G.S.X.
0.2726.2At5g07270830618ankyrin repeat family proteinF:ubiquitin-protein ligase activity, protein binding;P:N-terminal protein myristoylation;C:unknown;MOFBPVAO.I.H.G.S.X.
0.2726.2At4g32560829391paramyosin-relatedF:molecular_function unknown;P:biological_process unknown;C:unknown;MOBFAPVO.I.H.G.S.X.
0.2726.2At2g17190816224ubiquitin family proteinF:molecular_function unknown;P:protein modification process;C:unknown;MOPFBVAO.I.H.G.S.X.
0.2726.2At5g09850830845transcription elongation factor-relatedF:protein binding, transcription regulator activity, DNA binding;P:transcription;C:cytosol;MPOFBVO.I.H.G.S.X.
0.2624.4At4g16566827357histidine triad family protein / HIT family proteinF:nucleotide binding, catalytic activity;P:nucleotide metabolic process;C:peroxisome;BOMFAPO.I.H.G.S.X.
0.2624.4At3g05090819671transducin family protein / WD-40 repeat family proteinF:nucleotide binding;P:biological_process unknown;C:CUL4 RING ubiquitin ligase complex;MFOBPAVO.I.H.G.S.X.
0.2624.4At5g06260830513nucleolar protein-relatedF:calcium ion binding;P:N-terminal protein myristoylation;C:cellular_component unknown;MOPFO.I.H.G.S.X.
0.2624.4At5g64500836571membrane protein-relatedF:molecular_function unknown;P:biological_process unknown;C:membrane;BOFMAPO.I.H.G.S.X.
0.2624.4At5g32470833206-F:molecular_function unknown;P:biological_process unknown;C:mitochondrion;BOFAPMO.I.H.G.S.X.
0.2522.6At1g54370841878NHX5F:sodium:hydrogen antiporter activity, sodium ion transmembrane transporter activity;P:lithium ion transport, sodium ion transport;C:integral to membrane;BMOPFAO.I.H.G.S.X.
0.2522.6At3g01150821129PTB1 (POLYPYRIMIDINE TRACT-BINDING PROTEIN 1)Encodes one of the two polypyrimidine tract-binding (PTB) protein homologs in the Arabidopsis genome. Double mutants have defects in pollen germination.O.I.H.G.S.X.
0.2420.7At1g70570843394anthranilate phosphoribosyltransferase, putativeF:anthranilate phosphoribosyltransferase activity, transferase activity, transferring glycosyl groups;P:tryptophan biosynthetic process, metabolic process;C:chloroplast;BOAPO.I.H.G.S.X.
0.2319.3At3g25800822171PP2AA2 (PROTEIN PHOSPHATASE 2A SUBUNIT A2)one of three genes encoding the protein phosphatase 2A regulatory subunitO.I.H.G.S.X.
0.2319.3At3g54840824649ARA6Encodes a novel Rab-like GTP-ase that is localized to the peripheral membrane of the endosome.O.I.H.G.S.X.
0.2319.3At1g68100843138IAR1 (IAA-ALANINE RESISTANT 1)member of IAA-alanine resistance protein 1O.I.H.G.S.X.
0.2319.3At3g59770825146SAC9Encodes a phosphoinositide phosphatase. The sac9 null mutant accumulates elevated levels of PtdIns(4,5)P2 and Ins(1,4,5)P3. The mutant plants have characteristics of constitutive stress responses.O.I.H.G.S.X.
0.2217.5At4g26640828771WRKY20member of WRKY Transcription Factor; Group IO.I.H.G.S.X.
0.2217.5At3g03570821234-F:molecular_function unknown;P:biological_process unknown;C:cytosol;MPOO.I.H.G.S.X.
0.2217.5At5g43320834350ckl8 (Casein Kinase I-like 8)F:protein serine/threonine kinase activity, protein kinase activity, kinase activity, ATP binding;P:protein amino acid phosphorylation;C:cellular_component unknown;MOPBFVAO.I.H.G.S.X.
0.2217.5At1g09920837524TRAF-type zinc finger-relatedF:zinc ion binding;P:biological_process unknown;C:cellular_component unknown;MOFPO.I.H.G.S.X.
0.2217.5At5g53530835435VPS26A (VACUOLAR PROTEIN SORTING 26A)Homolog of yeast retromer subunit VPS26. Part of a retromer-like protein complex involved in endosome to lysosome protein transport.O.I.H.G.S.X.
0.2115.8At3g55830824749EPC1 (ECTOPICALLY PARTING CELLS)A member of the Glycosyltransferase Family 64, homologous to Poplar cambium-expressed GT64 gene. The EPC1 protein plays a critical role during plant development in maintaining the integrity of organs via cell-cell adhesion, thereby providing mechanical strength and facilitating the movement of metabolites throughout the plant.O.I.H.G.S.X.
0.2115.8At4g19350827676EMB3006 (embryo defective 3006)F:molecular_function unknown;P:embryonic development ending in seed dormancy;C:cellular_component unknown;PMFO.I.H.G.S.X.
0.2115.8At2g27600817306SKD1 (SUPPRESSOR OF K+ TRANSPORT GROWTH DEFECT1)Encodes a SKD1 (Suppressor of K+ Transport Growth Defect1) homolog. Localized to the cytoplasm and to multivesicular endosomes. Involved in multivesicular endosome function.O.I.H.G.S.X.
0.2014.4At5g46190834661KH domain-containing proteinF:RNA binding, nucleic acid binding;P:biological_process unknown;C:unknown;MPFOBO.I.H.G.S.X.
0.2014.4At2g35100818076ARAD1 (ARABINAN DEFICIENT 1)Putative glycosyltransferase, similar to other CAZy Family 47 proteins. The protein is predicted to be a type 2 membrane protein with a signal anchor and is predicted to be targeted to the secretory pathway and to have a single transmembrane helix near the N terminus; hence, the protein has the features expected for a type II membrane protein targeted to the Golgi vesicles. The gene was shown to be expressed in all tissues but particularly in vascular tissues of leaves and stems.O.I.H.G.S.X.
0.2014.4At5g53850835466haloacid dehalogenase-like hydrolase family proteinF:hydrolase activity, metal ion binding;P:unknown;C:chloroplast stroma, chloroplast;BMFOPAO.I.H.G.S.X.
0.1912.7At2g27900817335unknown proteinF:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;MPOO.I.H.G.S.X.
0.1912.7At5g08290830725YLS8Encodes Dim1 homolog.O.I.H.G.S.X.
0.1912.7At1g05430837044unknown proteinF:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;PO.I.H.G.S.X.
0.1710.2At4g17270827441Mo25 family proteinF:binding;P:biological_process unknown;C:plasma membrane;MFPOO.I.H.G.S.X.
0.168.8At1g10430837583PP2A-2Encodes one of two isoforms of the catalytic subunit of protein phosphatase 2A.O.I.H.G.S.X.

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