Co-expression analysis

Gene ID At5g58330
Gene name malate dehydrogenase (NADP), chloroplast, putative
Module size 52 genes
NF 0.44
%ile 62.8



Co-expression network

pink confeito: Transcription factor, green bicone: Binding protein, red cone: Enzyme protein, blue sphere: Other protein
large node: VF over 0.50, middle node: over 0.25, small node: below 0.25



Co-expressed genes

Click gene/probe ID to show a list of genes that are co-expressed with the gene.

VF %ile CC Gene ID Repr. ID Gene name Func. O.I. H.G. S.X. Other DB
1.00100.01.00At5g58330835945malate dehydrogenase (NADP), chloroplast, putativeF:oxidoreductase activity, binding, malate dehydrogenase activity, catalytic activity, malate dehydrogenase (NADP+) activity;P:malate metabolic process, carbohydrate metabolic process, metabolic process;C:in 6 components;BOMPFAO.I.H.G.S.X.
0.6075.70.95At2g27680817314aldo/keto reductase family proteinF:oxidoreductase activity, aldo-keto reductase activity;P:oxidation reduction;C:chloroplast stroma, chloroplast, chloroplast envelope, plant-type cell wall;BOFPAMO.I.H.G.S.X.
0.5974.70.95At4g30950829220FAD6 (FATTY ACID DESATURASE 6)Chloroplastic enzyme responsible for the synthesis of 16:2 and 18:2 fatty acids from galactolipids, sulpholipids and phosphatidylglycerol. Uses ferredoxin as electron donor. Gene mutation resulted in reduced level of unsaturated fatty acids leading to susceptibility to photoinhibition.O.I.H.G.S.X.
0.5773.80.96At5g62790836400DXR (1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE)1-Deoxy-d-xylulose 5-phosphate reductoisomerase (DXR) catalyzes the first committed step of the 2-C-methyl-d-erythritol 4-phosphate pathway for isoprenoid biosynthesis. In Arabidopsis, DXR is encoded by a single-copy gene. Arabidopsis DXR is targeted to plastids and localizes into chloroplasts of leaf cells. DXR knockout or strongly silenced lines have a seedling lethal, albino phenotype. Transgenic, partially silenced lines expressing 35S:DXR have a variegated phenotype.O.I.H.G.S.X.
0.5773.80.94At3g60750825246transketolase, putativeF:catalytic activity, transketolase activity;P:response to cadmium ion, response to salt stress;C:chloroplast stroma, chloroplast, chloroplast envelope;OBMFAPO.I.H.G.S.X.
0.5469.50.95At3g54660824631GR (GLUTATHIONE REDUCTASE)Encodes glutathione reductase that is most likely localized in the chloroplast.O.I.H.G.S.X.
0.5469.50.95At3g12780820461PGK1 (PHOSPHOGLYCERATE KINASE 1)nuclear phosphoglycerate kinase (PGK1)O.I.H.G.S.X.
0.5267.40.95At5g35630833535GS2 (GLUTAMINE SYNTHETASE 2)chloroplastic glutamine synthetaseO.I.H.G.S.X.
0.5267.40.95At4g20360827784ATRABE1B (ARABIDOPSIS RAB GTPASE HOMOLOG E1B)F:GTP binding, translation elongation factor activity, GTPase activity;P:peptidyl-cysteine S-nitrosylation;C:in 9 components;BOMFPAVO.I.H.G.S.X.
0.5267.40.95At5g47840834835AMK2 (Adenosine monophosphate kinase)F:nucleobase, nucleoside, nucleotide kinase activity, nucleotide kinase activity, ATP binding, adenylate kinase activity, phosphotransferase activity, phosphate group as acceptor;P:nucleobase, nucleoside, nucleotide and nucleic acid metabolic process, anaerobic respiration, nucleotide metabolic process;C:chloroplast, chloroplast stroma;BOMFPAO.I.H.G.S.X.
0.5166.30.96At1g44575841033NPQ4 (NONPHOTOCHEMICAL QUENCHING)Encoding PSII-S (CP22), a ubiquitous pigment-binding protein associated with photosystem II (PSII) of higher plants. Involved in nonphotochemical quenching rather than in photosynthesis. Mutant has a normal violaxanthin cycle but has a limited capacity of quenching singlet excited chlorophylls and is tolerant to lipid peroxidation.O.I.H.G.S.X.
0.5166.30.95At3g63410825516APG1 (ALBINO OR PALE GREEN MUTANT 1)Encodes a MPBQ/MSBQ methyltransferase located in the chloroplast inner envelope membrane. Mutant plants lack plastoquinone (PQ), suggesting that the APG1 protein is involved in the methylation step of PQ biosynthesis. The gene product is also involved in tocopherol (vitamin E) biosynthesis.O.I.H.G.S.X.
0.5065.30.96At5g30510833138RPS1 (RIBOSOMAL PROTEIN S1)F:structural constituent of ribosome, RNA binding;P:translation;C:thylakoid, chloroplast stroma, chloroplast, membrane;BOPMFAO.I.H.G.S.X.
0.5065.30.95At2g35490818114plastid-lipid associated protein PAP, putativeF:structural molecule activity;P:biological_process unknown;C:thylakoid, chloroplast thylakoid membrane, chloroplast, plastoglobule;PBOMO.I.H.G.S.X.
0.5065.30.95At5g27560832816unknown proteinF:molecular_function unknown;P:biological_process unknown;C:chloroplast;OBPO.I.H.G.S.X.
0.4963.50.95At5g57930835904APO2 (ACCUMULATION OF PHOTOSYSTEM ONE 2)ACCUMULATION OF PHOTOSYSTEM ONE 2O.I.H.G.S.X.
0.4761.20.96At4g14210827061PDS3 (PHYTOENE DESATURASE 3)Encodes phytoene desaturase (phytoene dehydrogenase), an enzyme that catalyzes the desaturation of phytoene to zeta-carotene during carotenoid biosynthesis. Processed protein is localized to the plastid.O.I.H.G.S.X.
0.4761.20.95At1g11860837733aminomethyltransferase, putativeF:aminomethyltransferase activity;P:response to cadmium ion;C:in 6 components;OBMFAPO.I.H.G.S.X.
0.4761.20.94At3g24430822033HCF101 (HIGH-CHLOROPHYLL-FLUORESCENCE 101)encodes a MRP-like protein with a nucleotide-binding domain.O.I.H.G.S.X.
0.4659.80.95At3g61870825360unknown proteinF:molecular_function unknown;P:biological_process unknown;C:chloroplast, chloroplast inner membrane, chloroplast envelope;BOPO.I.H.G.S.X.
0.4558.30.94At1g74470843788geranylgeranyl reductaseEncodes for a multifunctional protein with geranylgeranyl reductase activity shown to catalyze the reduction of prenylated geranylgeranyl-chlorophyll a to phytyl-chlorophyll a (chlorophyll a) and free geranylgeranyl pyrophosphate to phytyl pyrophosphate.O.I.H.G.S.X.
0.4558.30.95At2g34860818051EDA3 (embryo sac development arrest 3)F:unfolded protein binding, heat shock protein binding;P:megagametogenesis;C:chloroplast thylakoid membrane, chloroplast;BOPAMFO.I.H.G.S.X.
0.4558.30.94At5g16710831532DHAR3 (dehydroascorbate reductase 1)The protein undergoes thiolation following treatment with the oxidant tert-butylhydroperoxide.O.I.H.G.S.X.
0.4558.30.95At4g01150828181unknown proteinF:molecular_function unknown;P:biological_process unknown;C:thylakoid, chloroplast thylakoid membrane, chloroplast, plastoglobule, chloroplast envelope;PBOO.I.H.G.S.X.
0.4457.20.95At2g21170816652TIM (TRIOSEPHOSPHATE ISOMERASE)Encodes triosephosphate isomerase.O.I.H.G.S.X.
0.4457.20.94At2g28800817429ALB3 (ALBINO 3)member of Chloroplast membrane protein ALBINO3 familyO.I.H.G.S.X.
0.4457.20.94At3g08010819992ATAB2Encodes a chloroplast-localized protein ATAB2. ATAB2 is involved in the biogenesis of Photosystem I and II. ATAB2 has A/U-rich RNA-binding activity and presumably functions as an activator of translation with targets at PS I and PS II.O.I.H.G.S.X.
0.4457.20.95At3g116308203352-cys peroxiredoxin, chloroplast (BAS1)Encodes a 2-Cys peroxiredoxin (2-Cys PrxA) that contains two catalytic Cys residues.O.I.H.G.S.X.
0.4355.30.95At1g80030844343DNAJ heat shock protein, putativeF:unfolded protein binding, heat shock protein binding, ATP binding;P:protein folding, response to heat;C:chloroplast thylakoid membrane, chloroplast;OBMFPAVO.I.H.G.S.X.
0.4355.30.95At1g65260842833PTAC4 (PLASTID TRANSCRIPTIONALLY ACTIVE4)F:unknown;P:biological_process unknown;C:in 8 components;BOMVFPAO.I.H.G.S.X.
0.4355.30.95At3g55800824746SBPASE (sedoheptulose-bisphosphatase)Encodes the chloroplast enzyme sedoheptulose-1,7-bisphosphatase (SBPase), involved in the carbon reduction of the Calvin cycle. Increase in SBPase activity in transgenic lines accumulate up to 50% more sucrose and starch than wild-type.O.I.H.G.S.X.
0.4355.30.95At5g23120832376HCF136encodes a stability and/or assembly factor of photosystem IIO.I.H.G.S.X.
0.4253.90.94At4g21280827877oxygen-evolving enhancer protein 3, chloroplast, putative (PSBQ1) (PSBQ)Encodes the PsbQ subunit of the oxygen evolving complex of photosystem II.O.I.H.G.S.X.
0.4253.90.94At5g54770835567THI1Encodes a thiamine biosynthetic gene that has a dual function in thiamine biosynthesis and mitochondrial DNA damage tolerance. It appears to be involved in producing the thiazole portion of thiamine (vitamin B1). A crystal structure of the protein reveals that it forms a 2-ring homo-octamer.O.I.H.G.S.X.
0.4253.90.95At1g32160840108unknown proteinF:molecular_function unknown;P:biological_process unknown;C:chloroplast;PBOO.I.H.G.S.X.
0.4253.90.95At5g22830832346ATMGT10 (MAGNESIUM (MG) TRANSPORTER 10)putative Mg(2+) transport proteinO.I.H.G.S.X.
0.4253.90.95At3g56940824861CRD1 (COPPER RESPONSE DEFECT 1)Encodes a putative ZIP protein with varying mRNA accumulation in leaves, stems and roots. Has a consensus carboxylate-bridged di-iron binding site.O.I.H.G.S.X.
0.4050.80.94At1g42970840895GAPB (GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE B SUBUNIT)Encodes chloroplast localized glyceraldehyde-3-phosphate dehydrogenase.O.I.H.G.S.X.
0.3948.40.95At2g20890816623PSB29Chloroplast-localized Thylakoid formation1 gene product involved in vesicle-mediated formation of thylakoid membranes. Thf1 antisense lines contain abnormal chloroplasts early in leaf development (chloroplasts have loosely stacked thylakoid membranes). Expression was induced in the light and decreased under dark conditions. G-alpha interaction partner that functions downstream of the plasma membrane–delimited heterotrimeric G-protein (GPA1) in a D-glucose signaling pathway. Localized to both the outer plastid membrane and the stroma. Probably involved in the metabolic pathway that controls the assembly of the PS II complex.O.I.H.G.S.X.
0.3948.40.95At1g60950842386FED Aencodes a major leaf ferredoxinO.I.H.G.S.X.
0.3846.70.94At5g36700833635PGLP1 (2-PHOSPHOGLYCOLATE PHOSPHATASE 1)F:phosphoglycolate phosphatase activity;P:metabolic process;C:chloroplast stroma, chloroplast;BOMFAPO.I.H.G.S.X.
0.3745.00.95At3g07670819958SET domain-containing proteinF:[ribulose-bisphosphate carboxylase]-lysine N-methyltransferase activity;P:biological_process unknown;C:chloroplast;MFPOO.I.H.G.S.X.
0.3745.00.95At5g511108351854-alpha-hydroxytetrahydrobiopterin dehydrataseF:4-alpha-hydroxytetrahydrobiopterin dehydratase activity;P:tetrahydrobiopterin biosynthetic process;C:chloroplast;OBPAFO.I.H.G.S.X.
0.3745.00.95At4g04640825797ATPC1One of two genes (with ATPC2) encoding the gamma subunit of Arabidopsis chloroplast ATP synthase.O.I.H.G.S.X.
0.3745.00.94At1g12900837848GAPA-2 (GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE A SUBUNIT 2)F:NAD or NADH binding, glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity, binding, glyceraldehyde-3-phosphate dehydrogenase activity, catalytic activity;P:glycolysis, glucose metabolic process, metabolic process;C:apoplast, chloroplast stroma, chloroplast, membrane, chloroplast envelope;BOPFMAO.I.H.G.S.X.
0.3643.60.95At5g13510831195ribosomal protein L10 family proteinF:structural constituent of ribosome;P:translation, ribosome biogenesis;C:cytosolic ribosome, ribosome, chloroplast, chloroplast stroma;BOAPMFO.I.H.G.S.X.
0.3541.60.95At3g63490825524ribosomal protein L1 family proteinF:structural constituent of ribosome, RNA binding;P:translation, RNA processing;C:in 6 components;OBAFMPO.I.H.G.S.X.
0.3541.60.94At1g54780841919thylakoid lumen 18.3 kDa proteinF:molecular_function unknown;P:biological_process unknown;C:thylakoid, thylakoid lumen, chloroplast thylakoid membrane, chloroplast thylakoid lumen, chloroplast;BPOMO.I.H.G.S.X.
0.3541.60.94At3g10970820268haloacid dehalogenase-like hydrolase family proteinF:hydrolase activity, catalytic activity;P:metabolic process;C:chloroplast;BOPAMFO.I.H.G.S.X.
0.3439.80.94At4g03280827996PETC (PHOTOSYNTHETIC ELECTRON TRANSFER C)Encodes the Rieske FeS center of cytochrome b6f complex. Gene is expressed in shoot but not in root. Mutant has reduced electron transport at saturating light intensities and Q-cycle activity is hypersensitive to acidification of the thylakoid lumen.O.I.H.G.S.X.
0.3032.10.95At1g32550840149ferredoxin family proteinF:electron carrier activity, iron-sulfur cluster binding, 2 iron, 2 sulfur cluster binding;P:electron transport chain;C:unknown;BOPAMVFO.I.H.G.S.X.
0.3032.10.95At5g45390834575CLPP4 (CLP PROTEASE P4)One of several nuclear-encoded ClpPs (caseinolytic protease). Contains a highly conserved catalytic triad of Ser-type proteases (Ser-His-Asp). The name reflects nomenclature described in Adam et. al (2001).O.I.H.G.S.X.

Click More genes

Link to AtGenExpress Visualization Tool



Specific experiments for the module

Std2 GX %ile GSM ID Assay name GSE ID Experiment title Link to GEO
60.799.8GSM184556Whole roots 2hr KNO3 treated then incubated in protoplast-generating solution minus enzymes, biological rep2GSE7631Cell-specific nitrogen responses in the Arabidopsis rootLink to GEO
48.399.8GSM205426met1-3_leaf_second-selfed generation_rep02GSE8279Transgenerational Stability of the Arabidopsis Epigenome Is Coordinated by CG MethylationLink to GEO
47.999.8GSM205432Col_ leaf_ wildtype_rep01GSE8279Transgenerational Stability of the Arabidopsis Epigenome Is Coordinated by CG MethylationLink to GEO
42.599.8GSM143299High_Na_seg_pool_ts_col_F2GSE6203Rus_etal_High_Na_Arabidopsis_accessions_mapping_HKT1Link to GEO
41.599.8GSM143300Ts_genomic_hyb_3GSE6203Rus_etal_High_Na_Arabidopsis_accessions_mapping_HKT1Link to GEO
41.299.8GSM143301Ts_genomic_hyb_2GSE6203Rus_etal_High_Na_Arabidopsis_accessions_mapping_HKT1Link to GEO
40.199.8GSM143298Low_Na_seg_pool_ts_col_F2GSE6203Rus_etal_High_Na_Arabidopsis_accessions_mapping_HKT1Link to GEO
36.999.7GSM253649Col-0-2GSE10039Low_Mo_Arabidopsis_mapping_MOT1Link to GEO
36.899.7GSM205364met1-3_leaf_second-selfed generation_rep01GSE8279Transgenerational Stability of the Arabidopsis Epigenome Is Coordinated by CG MethylationLink to GEO
36.499.7GSM143307Low_Na_seg_pool_tsu_col_F2GSE6203Rus_etal_High_Na_Arabidopsis_accessions_mapping_HKT1Link to GEO
35.499.7GSM143302Ts_genomic_hyb_1GSE6203Rus_etal_High_Na_Arabidopsis_accessions_mapping_HKT1Link to GEO
33.899.7GSM143306High_Na_seg_pool_tsu_col_F2GSE6203Rus_etal_High_Na_Arabidopsis_accessions_mapping_HKT1Link to GEO
33.799.7GSM184551Whole roots 2hr KCl control treated then incubated in protoplast-generating solution minus enzymes, biological rep1GSE7631Cell-specific nitrogen responses in the Arabidopsis rootLink to GEO
33.399.7GSM253646Low_Mo_seg_pool_Ler_col_F2GSE10039Low_Mo_Arabidopsis_mapping_MOT1Link to GEO
33.199.7GSM253645High_Mo_seg_pool_Ler_col_F2GSE10039Low_Mo_Arabidopsis_mapping_MOT1Link to GEO
32.999.7GSM143309Tsu_genomic_hyb_2GSE6203Rus_etal_High_Na_Arabidopsis_accessions_mapping_HKT1Link to GEO
32.799.7GSM253647Col-0 3GSE10039Low_Mo_Arabidopsis_mapping_MOT1Link to GEO
32.699.7GSM143308Tsu_genomic_hyb_3GSE6203Rus_etal_High_Na_Arabidopsis_accessions_mapping_HKT1Link to GEO
32.199.7GSM253648Col-0-1GSE10039Low_Mo_Arabidopsis_mapping_MOT1Link to GEO
31.899.7GSM143310Tsu_genomic_hyb_1GSE6203Rus_etal_High_Na_Arabidopsis_accessions_mapping_HKT1Link to GEO
31.799.7GSM205430met1-3_leaf_fourth-selfed generation_rep02GSE8279Transgenerational Stability of the Arabidopsis Epigenome Is Coordinated by CG MethylationLink to GEO
31.499.7GSM253652Ler 2GSE10039Low_Mo_Arabidopsis_mapping_MOT1Link to GEO
30.499.7GSM205435Col_ leaf_ wildtype_rep02GSE8279Transgenerational Stability of the Arabidopsis Epigenome Is Coordinated by CG MethylationLink to GEO
29.999.7GSM253651Ler 1GSE10039Low_Mo_Arabidopsis_mapping_MOT1Link to GEO
28.799.7GSM253650Ler 3GSE10039Low_Mo_Arabidopsis_mapping_MOT1Link to GEO
27.399.7GSM205428met1-3_leaf_fourth-selfed generation_rep01GSE8279Transgenerational Stability of the Arabidopsis Epigenome Is Coordinated by CG MethylationLink to GEO
24.499.6E-MEXP-807-raw-cel-1173273144
23.499.6E-MEXP-807-raw-cel-1173273252
20.899.6GSM184923Arabidopsis, root cells, protophloem, 140 mM NaCl, replicate 2GSE7641Expression analysis of root cell-types after treatment with saltLink to GEO
18.899.5GSM184537Whole roots 2hr KCl control treated then frozen, biological rep1GSE7631Cell-specific nitrogen responses in the Arabidopsis rootLink to GEO
15.099.4GSM184906Arabidopsis, root cells, protophloem, standard conditions, replicate 3GSE7641Expression analysis of root cell-types after treatment with saltLink to GEO
14.899.4GSM184905Arabidopsis, root cells, protophloem, standard conditions, replicate 2GSE7641Expression analysis of root cell-types after treatment with saltLink to GEO
13.699.4GSM184904Arabidopsis, root cells, protophloem, standard conditions, replicate 1GSE7641Expression analysis of root cell-types after treatment with saltLink to GEO
10.599.2GSM176876AWP_AL_Txed_1GSE7334Microarray Analysis of Arabidopsis Genome Response to Aluminum StressLink to GEO
9.299.1E-MEXP-828-raw-cel-1156922386
8.999.0GSM311291Laser capture microdissected (LCM) chalazal endosperm at the linear-cotyledon stage, biological replicate 1GSE12403Expression data from Arabidopsis seed compartments at the linear-cotyledon stageLink to GEO

Biological processes inferred to relate to the module

SFGenesGO IDProcess NameLink to AmiGO
0.1033GO:0019253The fixation of carbon dioxide (CO2) as glucose in the chloroplasts of C3 plants; uses ATP and NADPH formed in the light reactions of photosynthesis; carbon dioxide reacts with ribulose 1,5-bisphosphate (catalyzed by the function of ribulose-bisphosphate carboxylase) to yield two molecules of 3-phosphoglycerate; these are then phosphorylated by ATP to 1,3-bisphosphateglyceraldehyde which, in turn, is then reduced by NADPH to glyceraldehyde 3-phosphate. The glyceraldehyde 3-phosphate is converted to fructose 5-phosphate and ribulose 5-phosphate by aldolase and other enzymes; the ribulose 5-phosphate is phosphorylated by ATP to ribulose 1,5-bisphosphate.Link to AmiGO
0.0863GO:0010027A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the thylakoid membrane.Link to AmiGO
0.0824GO:0006096The chemical reactions and pathways resulting in the breakdown of a monosaccharide (generally glucose) into pyruvate, with the concomitant production of a small amount of ATP. Pyruvate may be converted to ethanol, lactate, or other small molecules, or fed into the TCA cycle.Link to AmiGO

KEGG PATHWAY inferred to related to the module

SFGenesKEGG IDPathway nameLink to KEGG
0.110700710Carbon fixation in photosynthetic organismsLink to KEGG PATHWAY
0.080500195PhotosynthesisLink to KEGG PATHWAY
0.049601062Biosynthesis of terpenoids and steroidsLink to KEGG PATHWAY

Inter-species module comparison

Select a plant to compare co-expressed genes between species.
Glycine_max
Hordeum_vulgare
Oryza_sativa
Populus_trichocarpa
Triticum_aestivum
Vitis_vinifera
Zea_mays



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