Co-expression analysis

Gene ID At5g53950
Gene name CUC2 (CUP-SHAPED COTYLEDON 2)
Module size 38 genes
NF 0.14
%ile 10.8



Co-expression network

pink confeito: Transcription factor, green bicone: Binding protein, red cone: Enzyme protein, blue sphere: Other protein
large node: VF over 0.50, middle node: over 0.25, small node: below 0.25



Co-expressed genes

Click gene/probe ID to show a list of genes that are co-expressed with the gene.

VF %ile CC Gene ID Repr. ID Gene name Func. O.I. H.G. S.X. Other DB
0.7284.81.00At5g53950835478CUC2 (CUP-SHAPED COTYLEDON 2)Transcriptional activator of the NAC gene family, with CUC1 redundantly required for embryonic apical meristem formation, cotyledon separation and expression of STM. Proper timing of CUC2 expression is required to maintain the phyllotactic pattern initiated in the meristem. CUC2 expression in leaf sinus region is required for serration and the extent of serration is modulated by mir164A mediated repression of CUC2.O.I.H.G.S.X.
0.3541.60.82At4g27510828860unknown proteinF:molecular_function unknown;P:biological_process unknown;C:unknown;PO.I.H.G.S.X.
0.3439.80.83At2g21800816716ATEME1A (ARABIDOPSIS ESSENTIAL MEIOTIC ENDONUCLEASE 1A)Forms a complex with MUS81 that functions as endonuclease in DNA recombination and repair processes.O.I.H.G.S.X.
0.3032.10.83At5g48820834940ICK6 (INHIBITOR/INTERACTOR WITH CYCLIN-DEPENDENT KINASE)Kip-related protein (KRP) gene, encodes CDK (cyclin-dependent kinase) inhibitor (CKI), negative regulator of cell division. Binds to D type and CDC2A cyclins and may inhibit cell cycle. Seven KRP genes were found in Arabidopsis thaliana. Differential expression patterns for distinct KRPs were revealed by in situ hybridization.O.I.H.G.S.X.
0.2930.30.81At3g10310820193ATP binding / microtubule motorF:microtubule motor activity, ATP binding;P:microtubule-based movement;C:microtubule associated complex;MOFPO.I.H.G.S.X.
0.2930.30.83At3g48910--O.I.H.G.S.X.
0.2830.30.81At1g17920838371HDG12 (HOMEODOMAIN GLABROUS 12)Encodes a homeobox-leucine zipper family protein belonging to the HD-ZIP IV family. Together with HDG11, it is involved in trichome branching.O.I.H.G.S.X.
0.2830.30.81At1g27880839681ATP-dependent DNA helicase, putativeF:helicase activity, nucleic acid binding, ATP-dependent helicase activity, ATP binding;P:DNA recombination;C:cellular_component unknown;BOMFPVAO.I.H.G.S.X.
0.2522.60.81At3g58770825046unknown proteinF:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;POO.I.H.G.S.X.
0.2319.30.81At1g01370839104HTR12Encodes a centromere-identifying protein histone H3 variant. Localized at centromeres in both mitotic and meiotic cells.O.I.H.G.S.X.
0.2319.30.82At3g47460823900ATSMC2member of SMC subfamilyO.I.H.G.S.X.
0.2115.80.82At5g63920836513DNA topoisomerase III alpha, putativeF:DNA topoisomerase activity, DNA topoisomerase type I activity, DNA binding, zinc ion binding, nucleic acid binding;P:DNA topological change, DNA unwinding during replication, DNA metabolic process;C:chromosome;BOMPAFVO.I.H.G.S.X.
0.2014.40.81At5g23770832442RNA bindingF:RNA binding;P:unknown;C:unknown;POBFMO.I.H.G.S.X.
0.1912.70.82At1g09450837468haspin-relatedF:protein kinase activity, ATP binding;P:protein amino acid phosphorylation, N-terminal protein myristoylation;C:cellular_component unknown;MFOPO.I.H.G.S.X.
0.1912.70.81At4g18470827577SNI1Negative regulator of systemic acquired resistance (SAR), repressor of pathogenesis-related PR gene expression which is removed by NPR1 upon induction of SAR. Encodes leucine-rich nuclear protein. Conserved in plants, with putative orthologs found in several plant species. Many NPR1-dependent PR gene are specifically derepressed in the sni1 mutant. The structural similarity of SNI1 to Armadillo repeat proteins implies that SNI1 may form a scaffold for interaction with proteins that modulate transcription. Histone modification may be involved in SNI1-mediated repression of PR genes.O.I.H.G.S.X.
0.1710.20.82At4g39790830137unknown proteinF:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;PBFMOO.I.H.G.S.X.
0.1710.20.83At2g43990819004unknown proteinF:molecular_function unknown;P:biological_process unknown;C:chloroplast;OMBFPVO.I.H.G.S.X.
0.1710.20.83At3g18524821383MSH2 (MUTS HOMOLOG 2)Encodes a DNA mismatch repair homolog of human MutS gene, MSH6. MSH2 is involved in maintaining genome stability and repressing recombination of mismatched heteroduplexes.There are four MutS genes in Arabidopsis, MSH2, MSH3, MSH6, and MSH7, which all act as heterodimers and bind to 51-mer duplexes. MSH2 has different binding specificity to different mismatches in combination with MSH3, MSH6, or MSH7.O.I.H.G.S.X.
0.168.80.82At5g01910831775unknown proteinF:molecular_function unknown;P:biological_process unknown;C:unknown;MPOFO.I.H.G.S.X.
0.157.80.82At5g58280835940transcriptional factor B3 family proteinF:transcription factor activity, DNA binding;P:regulation of transcription, DNA-dependent;C:unknown;PO.I.H.G.S.X.
0.146.80.82At4g30700829193pentatricopeptide (PPR) repeat-containing proteinF:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;POMFO.I.H.G.S.X.
0.135.80.82At3g56300824797tRNA synthetase class I (C) family proteinF:cysteine-tRNA ligase activity, nucleotide binding, ATP binding;P:cysteinyl-tRNA aminoacylation, translation;C:cytoplasm;OBMFAPVO.I.H.G.S.X.
0.135.80.83At5g49390834999-F:unknown;P:unknown;C:endomembrane system;MOFBPVO.I.H.G.S.X.
0.135.80.81At5g27220832780protein transport protein-relatedF:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;MOBFPAVO.I.H.G.S.X.
0.135.80.83At3g06600819839unknown proteinF:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;PO.I.H.G.S.X.
0.135.80.81At4g39380830093-F:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;PO.I.H.G.S.X.
0.124.90.82At2g39880818575MYB25 (myb domain protein 25)Encodes a putative transcription factor (MYB25).O.I.H.G.S.X.
0.124.90.81At1g65470842858FAS1 (FASCIATA 1)Chromatin Assembly Factor-1 (CAF-1) p150 subunit. Mutants have reduced heterochromatin content. In Arabidopsis, the three CAF-1 subunits are encoded by FAS1, FAS2 and, most likely, MSI1, respectively. Mutations in FAS1 or FAS2 lead to increased frequency of homologous recombination and T-DNA integration in Arabidopsis.O.I.H.G.S.X.
0.114.10.82At3g11040820275glycosyl hydrolase family 85 proteinF:hydrolase activity, acting on glycosyl bonds, mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity;P:biological_process unknown;C:cytoplasm;BMOPFO.I.H.G.S.X.
0.103.40.82At5g23800832445agenet domain-containing proteinF:RNA binding;P:unknown;C:cellular_component unknown;POBMO.I.H.G.S.X.
0.092.80.81At4g25540828659MSH3 (Arabidopsis homolog of DNA mismatch repair protein MSH3)encodes a DNA mismatch repair homolog of human MutS gene, MSH6. There are four MutS genes in Arabidopsis, MSH2, MSH3, MSH6, and MSH7, which all act as heterodimers and bind to 51-mer duplexes. MSH2*MSH3 heterodimers bound 'insertion-deletion' DNA with three nucleotides (+AAG) or one nucleotide (+T) looped out much better than they bound DNA with a base/base mispair (T/G).O.I.H.G.S.X.
0.092.80.82At1g60860842378AGD2 (ARF-GAP DOMAIN 2)A member of ARF GAP domain (AGD), A thaliana has 15 members, grouped into four classes. AGD2 belongs to the class 1, together with AGD1, AGD3, and AGD4.O.I.H.G.S.X.
0.082.30.81At2g20210816540leucine-rich repeat family proteinF:protein binding;P:unknown;C:endomembrane system;MOPBFO.I.H.G.S.X.
0.071.90.81At4g39530830107pentatricopeptide (PPR) repeat-containing proteinF:binding;P:biological_process unknown;C:unknown;POMFBAO.I.H.G.S.X.
0.071.90.82At4g16570827358PRMT7 (PROTEIN ARGININE METHYLTRANSFERASE 7)F:methyltransferase activity;P:protein amino acid methylation;C:chloroplast;MFOPBAO.I.H.G.S.X.
0.071.90.81At2g45870819195unknown proteinF:molecular_function unknown;P:biological_process unknown;C:unknown;BFPOO.I.H.G.S.X.
0.061.40.82At1g26190839160phosphoribulokinase/uridine kinase family proteinF:adenylate cyclase activity, kinase activity, phosphotransferase activity, alcohol group as acceptor, ATP binding;P:biosynthetic process, cAMP biosynthetic process, metabolic process;C:cellular_component unknown;BOMPFAVO.I.H.G.S.X.
0.061.40.82At1g58470842216ATRBP1 (ARABIDOPSIS THALIANA RNA-BINDING PROTEIN 1)encodes an RNA-binding proteinO.I.H.G.S.X.

Click More genes

Link to AtGenExpress Visualization Tool



Specific experiments for the module

Std2 GX %ile GSM ID Assay name GSE ID Experiment title Link to GEO
99.099.9GSM133762Lindsey_1-14_torpedo-root_Rep1_ATH1GSE5730Transcriptional profiling of laser-capture micro-dissected embryonic tissuesLink to GEO
80.999.9GSM205432Col_ leaf_ wildtype_rep01GSE8279Transgenerational Stability of the Arabidopsis Epigenome Is Coordinated by CG MethylationLink to GEO
52.799.8GSM253649Col-0-2GSE10039Low_Mo_Arabidopsis_mapping_MOT1Link to GEO
51.099.8GSM253646Low_Mo_seg_pool_Ler_col_F2GSE10039Low_Mo_Arabidopsis_mapping_MOT1Link to GEO
50.199.8GSM143307Low_Na_seg_pool_tsu_col_F2GSE6203Rus_etal_High_Na_Arabidopsis_accessions_mapping_HKT1Link to GEO
49.099.8GSM143298Low_Na_seg_pool_ts_col_F2GSE6203Rus_etal_High_Na_Arabidopsis_accessions_mapping_HKT1Link to GEO
46.699.8GSM253648Col-0-1GSE10039Low_Mo_Arabidopsis_mapping_MOT1Link to GEO
46.499.8GSM143299High_Na_seg_pool_ts_col_F2GSE6203Rus_etal_High_Na_Arabidopsis_accessions_mapping_HKT1Link to GEO
46.399.8GSM143310Tsu_genomic_hyb_1GSE6203Rus_etal_High_Na_Arabidopsis_accessions_mapping_HKT1Link to GEO
45.699.8GSM253647Col-0 3GSE10039Low_Mo_Arabidopsis_mapping_MOT1Link to GEO
44.399.8GSM143306High_Na_seg_pool_tsu_col_F2GSE6203Rus_etal_High_Na_Arabidopsis_accessions_mapping_HKT1Link to GEO
43.299.8GSM253645High_Mo_seg_pool_Ler_col_F2GSE10039Low_Mo_Arabidopsis_mapping_MOT1Link to GEO
43.099.8GSM143300Ts_genomic_hyb_3GSE6203Rus_etal_High_Na_Arabidopsis_accessions_mapping_HKT1Link to GEO
42.599.8GSM143301Ts_genomic_hyb_2GSE6203Rus_etal_High_Na_Arabidopsis_accessions_mapping_HKT1Link to GEO
41.199.8GSM205426met1-3_leaf_second-selfed generation_rep02GSE8279Transgenerational Stability of the Arabidopsis Epigenome Is Coordinated by CG MethylationLink to GEO
40.299.8GSM143308Tsu_genomic_hyb_3GSE6203Rus_etal_High_Na_Arabidopsis_accessions_mapping_HKT1Link to GEO
40.099.8GSM184556Whole roots 2hr KNO3 treated then incubated in protoplast-generating solution minus enzymes, biological rep2GSE7631Cell-specific nitrogen responses in the Arabidopsis rootLink to GEO
38.899.8GSM205364met1-3_leaf_second-selfed generation_rep01GSE8279Transgenerational Stability of the Arabidopsis Epigenome Is Coordinated by CG MethylationLink to GEO
37.799.7GSM253651Ler 1GSE10039Low_Mo_Arabidopsis_mapping_MOT1Link to GEO
37.799.7GSM143309Tsu_genomic_hyb_2GSE6203Rus_etal_High_Na_Arabidopsis_accessions_mapping_HKT1Link to GEO
37.599.7GSM143302Ts_genomic_hyb_1GSE6203Rus_etal_High_Na_Arabidopsis_accessions_mapping_HKT1Link to GEO
37.399.7GSM253650Ler 3GSE10039Low_Mo_Arabidopsis_mapping_MOT1Link to GEO
36.999.7GSM205435Col_ leaf_ wildtype_rep02GSE8279Transgenerational Stability of the Arabidopsis Epigenome Is Coordinated by CG MethylationLink to GEO
36.799.7GSM253652Ler 2GSE10039Low_Mo_Arabidopsis_mapping_MOT1Link to GEO
33.299.7GSM133304RIKEN-NAKABAYASHI1BGSE5700AtGenExpress: Effect of ABA during seed imbibitionLink to GEO
30.699.7GSM133303RIKEN-NAKABAYASHI1AGSE5700AtGenExpress: Effect of ABA during seed imbibitionLink to GEO
26.699.7GSM284386Arabidopsis GSUS3GSE11262Expression data from Arabidopsis Seed Compartments at the Globular Embryo Stage.Link to GEO
25.899.7GSM205428met1-3_leaf_fourth-selfed generation_rep01GSE8279Transgenerational Stability of the Arabidopsis Epigenome Is Coordinated by CG MethylationLink to GEO
24.599.6GSM284392Arabidopsis GCE1GSE11262Expression data from Arabidopsis Seed Compartments at the Globular Embryo Stage.Link to GEO
23.999.6GSM205430met1-3_leaf_fourth-selfed generation_rep02GSE8279Transgenerational Stability of the Arabidopsis Epigenome Is Coordinated by CG MethylationLink to GEO
23.299.6GSM284387Arabidopsis GSUS4bGSE11262Expression data from Arabidopsis Seed Compartments at the Globular Embryo Stage.Link to GEO
22.299.6GSM133117RIKEN-YAMAUCHI1AGSE5687AtGenExpress: Different temperature treatment of seedsLink to GEO
20.499.6E-MEXP-1138-raw-cel-1432773258
19.199.6GSM284394Arabidopsis GCE3GSE11262Expression data from Arabidopsis Seed Compartments at the Globular Embryo Stage.Link to GEO
17.599.5E-MEXP-1138-raw-cel-1432773290
16.499.5GSM184537Whole roots 2hr KCl control treated then frozen, biological rep1GSE7631Cell-specific nitrogen responses in the Arabidopsis rootLink to GEO
13.899.4E-MEXP-1138-raw-cel-1432773322
12.699.3GSM133766Lindsey_1-18_torpedo-root_Rep3_ATH1GSE5730Transcriptional profiling of laser-capture micro-dissected embryonic tissuesLink to GEO
12.699.3GSM131453AtGen_6-9321_Heatstress-Roots-3.0h_Rep1GSE5628AtGenExpress: Stress Treatments (Heat stress)Link to GEO
12.499.3GSM284393Arabidopsis GCE2GSE11262Expression data from Arabidopsis Seed Compartments at the Globular Embryo Stage.Link to GEO
12.299.3GSM133773Lindsey_1-25_torpedo-meristem_Rep1_ATH1GSE5730Transcriptional profiling of laser-capture micro-dissected embryonic tissuesLink to GEO
12.099.3E-MEXP-509-raw-cel-829148561
11.999.3GSM133760Lindsey_1-12_heart-stage-root_Rep3_ATH1GSE5730Transcriptional profiling of laser-capture micro-dissected embryonic tissuesLink to GEO
11.699.3GSM131454AtGen_6-9322_Heatstress-Roots-3.0h_Rep2GSE5628AtGenExpress: Stress Treatments (Heat stress)Link to GEO
11.499.3GSM184551Whole roots 2hr KCl control treated then incubated in protoplast-generating solution minus enzymes, biological rep1GSE7631Cell-specific nitrogen responses in the Arabidopsis rootLink to GEO
9.599.1E-MEXP-1592-raw-cel-1617526984

Biological processes inferred to relate to the module

SFGenesGO IDProcess NameLink to AmiGO
0.0943GO:0006310Any process by which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Intrachromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction.Link to AmiGO
0.0752GO:0006298A system for the correction of errors in which an incorrect base, which cannot form hydrogen bonds with the corresponding base in the parent strand, is incorporated into the daughter strand. The mismatch repair system promotes genomic fidelity by repairing base-base mismatches, insertion-deletion loops and heterologies generated during DNA replication and recombination.Link to AmiGO
0.0562GO:0008283The multiplication or reproduction of cells, resulting in the expansion of a cell population.Link to AmiGO

KEGG PATHWAY inferred to related to the module

SFGenesKEGG IDPathway nameLink to KEGG
0.063203430Mismatch repairLink to KEGG PATHWAY
0.032103440Homologous recombinationLink to KEGG PATHWAY
0.024100970Aminoacyl-tRNA biosynthesisLink to KEGG PATHWAY

Inter-species module comparison

Select a plant to compare co-expressed genes between species.
Glycine_max
Hordeum_vulgare
Oryza_sativa
Populus_trichocarpa
Triticum_aestivum
Vitis_vinifera
Zea_mays



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