Co-expression analysis

Gene ID At4g16845
Gene name VRN2 (REDUCED VERNALIZATION RESPONSE 2)
Module size 63 genes
NF 0.34
%ile 46.1



Co-expression network

pink confeito: Transcription factor, green bicone: Binding protein, red cone: Enzyme protein, blue sphere: Other protein
large node: VF over 0.50, middle node: over 0.25, small node: below 0.25



Co-expressed genes

Click gene/probe ID to show a list of genes that are co-expressed with the gene.

VF %ile CC Gene ID Repr. ID Gene name Func. O.I. H.G. S.X. Other DB
1.00100.01.00At4g16845827392VRN2 (REDUCED VERNALIZATION RESPONSE 2)The VERNALIZATION2 (VRN2) gene mediates vernalization and encodes a nuclear-localized zinc finger protein with similarity to Polycomb group (PcG) proteins of plants and animals. In wild-type Arabidopsis, vernalization results in the stable reduction of the levels of the floral repressor FLC. In vrn2 mutants, FLC expression is downregulated normally in response to vernalization, but instead of remaining low, FLC mRNA levels increase when plants are returned to normal temperatures. VRN2 maintains FLC repression after a cold treatment, serving as a mechanism for the cellular memory of vernalization. Required for complete repression of FLC. Required for the methylation of histone H3O.I.H.G.S.X.
0.5065.30.91At3g12010820375-F:molecular_function unknown;P:biological_process unknown;C:unknown;MOPO.I.H.G.S.X.
0.5065.30.91At5g58440835957SNX2a (SORTING NEXIN 2a)F:phosphoinositide binding;P:signal transduction, intracellular signaling cascade;C:cellular_component unknown;MFOPABO.I.H.G.S.X.
0.4862.50.92At3g07180819905GPI transamidase component PIG-S-relatedF:molecular_function unknown;P:biological_process unknown;C:endoplasmic reticulum, plasma membrane;MFPOO.I.H.G.S.X.
0.4761.20.92At4g32620829397nucleic acid bindingF:nucleic acid binding;P:biological_process unknown;C:cellular_component unknown;OPMFBO.I.H.G.S.X.
0.4558.30.93At5g06120830499Ran-binding protein, putativeF:protein transporter activity, binding;P:intracellular protein transport, protein import into nucleus, docking;C:nucleus, nuclear pore, cytoplasm;MOPO.I.H.G.S.X.
0.4355.30.92At3g55480824714adaptin family proteinF:protein binding, binding;P:intracellular protein transport, vesicle-mediated transport;C:membrane coat, endomembrane system;BMFOPO.I.H.G.S.X.
0.4355.30.92At5g27970832867bindingF:binding;P:biological_process unknown;C:cellular_component unknown;MFOPBO.I.H.G.S.X.
0.4253.90.91At1g78800844216glycosyl transferase family 1 proteinF:transferase activity, transferring glycosyl groups;P:biosynthetic process;C:cellular_component unknown;BOAPMFO.I.H.G.S.X.
0.4253.90.91At1g60220842317ULP1D (UB-LIKE PROTEASE 1D)Encodes a deSUMOylating enzyme. In vitro it has both peptidase activity and isopeptidase activity: it can cleave C-terminal residues from SUMO to activate it for attachment to a target protein and it can also act on the isopeptide bond between SUMO and another protein. sGFP:OTS1 protein accumulates in the nucleus. Double mutant analysis with ULP1C/OTS2 indicates that these genes are involved in salt stress responses and flowering time regulation. Over-expression of 35S:OTS1 increases salt tolerance and reduces the level of SUMO-conjugated proteins. OTS1 transcript levels do not appear to change in response to salt, but, salt stress reduces the level of OTS1 protein in a proteasome-dependent manner.O.I.H.G.S.X.
0.4253.90.91At3g07160819903ATGSL10 (glucan synthase-like 10)Encodes GSL10, a member of the Glucan Synthase-Like (GSL) family believed to be involved in the synthesis of the cell wall component callose. GSL10 is required for male gametophyte development and plant growth. Has a role in entry of microspores into mitosis. GSL10 mutation leads to perturbation of microspore division symmetry, irregular callose deposition and failure of generative cell engulfment by the vegetative cell cytoplasm. Also refer to GSL8 (At2g36850).O.I.H.G.S.X.
0.4152.40.91At2g35630818131MOR1 (MICROTUBULE ORGANIZATION 1)Member of the MAP215 family of microtubule-associated proteins required to establish interphase arrays of cortical microtubules.Mutants have defects in cytokinesis during pollen development. Vegetative phenotypes observed in temperature sensitive mutants include left-handed organ twisting, isotropic cell expansion and impairment of root hair polarity.O.I.H.G.S.X.
0.4152.40.92At4g15880827269ESD4 (EARLY IN SHORT DAYS 4)EARLY IN SHORT DAYS 4 Arabidopsis mutant shows extreme early flowering and alterations in shoot development. It encodes a SUMO protease, located predominantly at the periphery of the nucleus. Accelerates the transition from vegetative growth to flowering. Probably acts in the same pathway as NUA in affecting flowering time, vegetative and inflorescence development.O.I.H.G.S.X.
0.4152.40.91At1g53050841739protein kinase family proteinF:protein serine/threonine kinase activity, protein kinase activity, kinase activity, ATP binding;P:protein amino acid phosphorylation, N-terminal protein myristoylation;C:plasma membrane;MPOFBVAO.I.H.G.S.X.
0.4050.80.92At5g23390832403unknown proteinF:molecular_function unknown;P:unknown;C:cellular_component unknown;PO.I.H.G.S.X.
0.4050.80.91At5g19660832086S1P (SITE-1 PROTEASE)S1P appears to function as a Golgi-localized subtilase and to help protect seedlings against salt and osmotic stress. The roots of s1p-3 mutants are hypersensitive to NaCl, KCl, LiCl, and mannitol. Several salt-stress responsive genes show weaker induction in an s1P-3 mutant background. The proteolytic cleavage of the bZIP17 transcription factor depends on S1P in vitro. And there is evidence that S1P can cleave bZIP17 in vitro.O.I.H.G.S.X.
0.4050.80.92At5g11040830971-F:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;MFOPO.I.H.G.S.X.
0.4050.80.91At5g18580831976FASS (FASS 1)fass mutants have aberrant cell shapes due to defects in arrangement of cortical microtubules. Encodes a protein highly conserved in higher plants and similar in its C-terminal part to B' regulatory subunits of type 2A protein phosphatases. Interacts with an Arabidopsis type A subunit of PP2A in the yeast two-hybrid system.O.I.H.G.S.X.
0.4050.80.92At1g54610841903protein kinase family proteinF:protein serine/threonine kinase activity, protein tyrosine kinase activity, protein kinase activity, kinase activity, ATP binding;P:protein amino acid phosphorylation, N-terminal protein myristoylation;C:plasma membrane;MPOFBVAO.I.H.G.S.X.
0.3948.40.91At2g46560819268transducin family protein / WD-40 repeat family proteinF:nucleotide binding;P:unknown;C:CUL4 RING ubiquitin ligase complex;BFMOPO.I.H.G.S.X.
0.3948.40.92At3g58580825027hydrolaseF:hydrolase activity;P:unknown;C:cellular_component unknown;MFOPBO.I.H.G.S.X.
0.3948.40.91At5g16280831488unknown proteinF:unknown;P:biological_process unknown;C:endomembrane system;MFOPVO.I.H.G.S.X.
0.3846.70.91At5g26240832693CLC-D (CHLORIDE CHANNEL D)member of Anion channel protein familyO.I.H.G.S.X.
0.3643.60.91At1g31780840065-F:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;MFPOBO.I.H.G.S.X.
0.3643.60.92At3g51310824294VPS35C (VPS35 HOMOLOG C)Homolog of yeast retromer subunit VPS35. Part of a retromer-like protein complex involved in endosome to lysosome protein transport.O.I.H.G.S.X.
0.3643.60.92At2g32170817776-F:unknown;P:unknown;C:cellular_component unknown;MFOPO.I.H.G.S.X.
0.3541.60.91At5g02850831762hydroxyproline-rich glycoprotein family proteinF:molecular_function unknown;P:biological_process unknown;C:unknown;MOFPBO.I.H.G.S.X.
0.3541.60.92At4g38500830007unknown proteinF:unknown;P:unknown;C:Golgi apparatus;POBAO.I.H.G.S.X.
0.3541.60.91At5g49950835059embryogenesis-associated protein-relatedF:molecular_function unknown;P:biological_process unknown;C:endomembrane system;BOMFPO.I.H.G.S.X.
0.3541.60.91At1g16010838171magnesium transporter CorA-like family protein (MRS2-1)F:metal ion transmembrane transporter activity;P:metal ion transport;C:vacuole, membrane;PFOMBAO.I.H.G.S.X.
0.3541.60.91At3g51050824269FG-GAP repeat-containing proteinF:molecular_function unknown;P:cell-matrix adhesion;C:integrin complex, integral to membrane, plasma membrane;OPMO.I.H.G.S.X.
0.3541.60.91At5g24350832505-F:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;MPFOBO.I.H.G.S.X.
0.3541.60.92At5g59560836075SRR1 (SENSITIVITY TO RED LIGHT REDUCED 1)Encodes a novel protein conserved in higher eukaryotes. Normal function of the protein is required for normal oscillator function during circadian rhythm. Mutant analyses also suggest a role in phytochrome B (phyB)-mediated light signaling.O.I.H.G.S.X.
0.3439.80.91At5g46210834663CUL4 (CULLIN4)Arabidopsis CULLIN4 (CUL4) forms an E3 ubiquitin ligase with the CDD complex and a common catalytic subunit RBX1 in mediating light control of development. This CUL4-based E3 ligase is essential for the repression of photomorphogenesis. The partial loss of CUL4 function resulted in a constitutive photomorphogenic phenotype with respect to morphogenesis and light-regulated gene expression. CUL4 exhibits a synergistic genetic interaction with COP10 and DET1.O.I.H.G.S.X.
0.3439.80.92At1g34550840358EMB2756 (EMBRYO DEFECTIVE 2756)F:unknown;P:embryonic development ending in seed dormancy, response to cadmium ion;C:unknown;OPMFBAO.I.H.G.S.X.
0.3439.80.91At1g80930844433MIF4G domain-containing protein / MA3 domain-containing proteinF:protein binding, RNA binding, binding;P:translation, RNA metabolic process;C:cytosol, nucleus;MOFBPVAO.I.H.G.S.X.
0.3338.10.91At1g22860838891unknown proteinF:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;MFOPBO.I.H.G.S.X.
0.3338.10.91At4g33200829456XI-Imember of Myosin-like proteinsO.I.H.G.S.X.
0.3338.10.91At1g79810844320TED3 (REVERSAL OF THE DET PHENOTYPE 3)Dominant suppressor of det1 phenotypes. Encodes a peroxisomal protein essential for Arabidopsis growth. Inserted directly from the cytosol into peroxisomes.O.I.H.G.S.X.
0.3338.10.91At3g22990821873LFR (LEAF AND FLOWER RELATED)Armadillo-repeat containing protein. Involved in leaf and flower development. Located in nucleus. Broadly expressed throughout vegetative and floral tissues.O.I.H.G.S.X.
0.3338.10.91At4g38200829976guanine nucleotide exchange family proteinF:binding, ARF guanyl-nucleotide exchange factor activity, guanyl-nucleotide exchange factor activity;P:regulation of ARF protein signal transduction;C:chloroplast;MFOPBO.I.H.G.S.X.
0.3338.10.91At2g35100818076ARAD1 (ARABINAN DEFICIENT 1)Putative glycosyltransferase, similar to other CAZy Family 47 proteins. The protein is predicted to be a type 2 membrane protein with a signal anchor and is predicted to be targeted to the secretory pathway and to have a single transmembrane helix near the N terminus; hence, the protein has the features expected for a type II membrane protein targeted to the Golgi vesicles. The gene was shown to be expressed in all tissues but particularly in vascular tissues of leaves and stems.O.I.H.G.S.X.
0.3338.10.91At2g05230815071DNAJ heat shock N-terminal domain-containing proteinF:heat shock protein binding;P:protein folding;C:cellular_component unknown;BOMPFAVO.I.H.G.S.X.
0.3235.70.91At4g36960829850RNA recognition motif (RRM)-containing proteinF:RNA binding, nucleotide binding, nucleic acid binding;P:biological_process unknown;C:cellular_component unknown;MPOFBAO.I.H.G.S.X.
0.3235.70.91At3g26370822241unknown proteinF:unknown;P:unknown;C:Golgi apparatus;PO.I.H.G.S.X.
0.3032.10.91At5g46190834661KH domain-containing proteinF:RNA binding, nucleic acid binding;P:biological_process unknown;C:unknown;MPFOBO.I.H.G.S.X.
0.3032.10.91At5g11490831021adaptin family proteinF:protein transporter activity, protein binding, binding;P:intracellular protein transport, vesicle-mediated transport, protein transport;C:membrane coat, clathrin adaptor complex;MFOPO.I.H.G.S.X.
0.3032.10.91At1g73720843707transducin family protein / WD-40 repeat family proteinF:nucleotide binding;P:biological_process unknown;C:CUL4 RING ubiquitin ligase complex;MFOBPAVO.I.H.G.S.X.
0.3032.10.91At3g59770825146SAC9Encodes a phosphoinositide phosphatase. The sac9 null mutant accumulates elevated levels of PtdIns(4,5)P2 and Ins(1,4,5)P3. The mutant plants have characteristics of constitutive stress responses.O.I.H.G.S.X.
0.2930.30.91At4g24840828587-F:molecular_function unknown;P:protein transport, Golgi organization;C:vacuole;MFOPO.I.H.G.S.X.
0.2930.30.92At5g28850833004calcium-binding EF hand family proteinF:calcium ion binding;P:biological_process unknown;C:endomembrane system;MOPFO.I.H.G.S.X.
0.2930.30.91At1g55130841956endomembrane protein 70, putativeF:unknown;P:unknown;C:integral to membrane, Golgi apparatus;MPOFBO.I.H.G.S.X.
0.2830.30.91At3g23900821973RNA recognition motif (RRM)-containing proteinF:nucleotide binding, nucleic acid binding;P:biological_process unknown;C:cellular_component unknown;MOFBPVAO.I.H.G.S.X.
0.2830.30.92At5g18190831937protein kinase family proteinF:protein serine/threonine kinase activity, protein kinase activity, kinase activity, ATP binding;P:protein amino acid phosphorylation;C:cellular_component unknown;MBOPFVAO.I.H.G.S.X.
0.2830.30.91At1g55150841958DEAD box RNA helicase, putative (RH20)F:helicase activity, ATP-dependent helicase activity, ATP binding, nucleic acid binding;P:unknown;C:cellular_component unknown;BOMFPAVO.I.H.G.S.X.
0.2830.30.91At3g22170821781FHY3 (FAR-RED ELONGATED HYPOCOTYLS 3)A component of the PHYA signaling network, mediates the FR-HIR response to far-red light in concert with FAR1.O.I.H.G.S.X.
0.2726.20.91At1g11060837647unknown proteinF:molecular_function unknown;P:biological_process unknown;C:cellular_component unknown;MBPOFO.I.H.G.S.X.
0.2624.40.91At2g25760817118protein kinase family proteinF:protein serine/threonine kinase activity, protein kinase activity, kinase activity, ATP binding;P:protein amino acid phosphorylation;C:unknown;MBOPFVAO.I.H.G.S.X.
0.2624.40.91At3g17430821007phosphate translocator-relatedF:organic anion transmembrane transporter activity;P:unknown;C:endomembrane system;PMFOBO.I.H.G.S.X.
0.2522.60.91At1g16570838227glycosyl transferase family 1 proteinF:transferase activity, transferring glycosyl groups;P:biosynthetic process;C:mitochondrion;BMOFPAO.I.H.G.S.X.
0.2319.30.91At5g15880831445unknown proteinF:molecular_function unknown;P:unknown;C:cellular_component unknown;MOBFPAVO.I.H.G.S.X.
0.1912.70.91At3g04610819619FLK (flowering locus KH domain)F:RNA binding, nucleic acid binding;P:positive regulation of flower development;C:nucleus;MOPFVBO.I.H.G.S.X.
0.157.80.91At3g50520824216phosphoglycerate/bisphosphoglycerate mutase family proteinF:catalytic activity;P:metabolic process;C:cellular_component unknown;BOMFPAO.I.H.G.S.X.

Click More genes

Link to AtGenExpress Visualization Tool



Specific experiments for the module

Std2 GX %ile GSM ID Assay name GSE ID Experiment title Link to GEO
52.899.8GSM184556Whole roots 2hr KNO3 treated then incubated in protoplast-generating solution minus enzymes, biological rep2GSE7631Cell-specific nitrogen responses in the Arabidopsis rootLink to GEO
52.699.8GSM143309Tsu_genomic_hyb_2GSE6203Rus_etal_High_Na_Arabidopsis_accessions_mapping_HKT1Link to GEO
52.399.8GSM143308Tsu_genomic_hyb_3GSE6203Rus_etal_High_Na_Arabidopsis_accessions_mapping_HKT1Link to GEO
49.999.8GSM253646Low_Mo_seg_pool_Ler_col_F2GSE10039Low_Mo_Arabidopsis_mapping_MOT1Link to GEO
49.799.8GSM253649Col-0-2GSE10039Low_Mo_Arabidopsis_mapping_MOT1Link to GEO
48.699.8GSM143307Low_Na_seg_pool_tsu_col_F2GSE6203Rus_etal_High_Na_Arabidopsis_accessions_mapping_HKT1Link to GEO
47.099.8GSM143306High_Na_seg_pool_tsu_col_F2GSE6203Rus_etal_High_Na_Arabidopsis_accessions_mapping_HKT1Link to GEO
46.599.8GSM253645High_Mo_seg_pool_Ler_col_F2GSE10039Low_Mo_Arabidopsis_mapping_MOT1Link to GEO
45.299.8GSM143310Tsu_genomic_hyb_1GSE6203Rus_etal_High_Na_Arabidopsis_accessions_mapping_HKT1Link to GEO
43.899.8GSM143298Low_Na_seg_pool_ts_col_F2GSE6203Rus_etal_High_Na_Arabidopsis_accessions_mapping_HKT1Link to GEO
43.799.8GSM253648Col-0-1GSE10039Low_Mo_Arabidopsis_mapping_MOT1Link to GEO
43.199.8GSM253647Col-0 3GSE10039Low_Mo_Arabidopsis_mapping_MOT1Link to GEO
41.399.8GSM143301Ts_genomic_hyb_2GSE6203Rus_etal_High_Na_Arabidopsis_accessions_mapping_HKT1Link to GEO
40.999.8GSM143299High_Na_seg_pool_ts_col_F2GSE6203Rus_etal_High_Na_Arabidopsis_accessions_mapping_HKT1Link to GEO
40.799.8GSM253651Ler 1GSE10039Low_Mo_Arabidopsis_mapping_MOT1Link to GEO
39.999.8GSM253650Ler 3GSE10039Low_Mo_Arabidopsis_mapping_MOT1Link to GEO
39.799.8GSM143300Ts_genomic_hyb_3GSE6203Rus_etal_High_Na_Arabidopsis_accessions_mapping_HKT1Link to GEO
38.199.8GSM253652Ler 2GSE10039Low_Mo_Arabidopsis_mapping_MOT1Link to GEO
36.999.7GSM143302Ts_genomic_hyb_1GSE6203Rus_etal_High_Na_Arabidopsis_accessions_mapping_HKT1Link to GEO
23.799.6GSM226530LCOLUMELLASBGSE8934A high resolution organ expression map reveals novel expression patterns and predicts cellular functionLink to GEO
23.199.6GSM284393Arabidopsis GCE2GSE11262Expression data from Arabidopsis Seed Compartments at the Globular Embryo Stage.Link to GEO
22.799.6GSM184551Whole roots 2hr KCl control treated then incubated in protoplast-generating solution minus enzymes, biological rep1GSE7631Cell-specific nitrogen responses in the Arabidopsis rootLink to GEO
21.899.6GSM184537Whole roots 2hr KCl control treated then frozen, biological rep1GSE7631Cell-specific nitrogen responses in the Arabidopsis rootLink to GEO
21.199.6GSM205435Col_ leaf_ wildtype_rep02GSE8279Transgenerational Stability of the Arabidopsis Epigenome Is Coordinated by CG MethylationLink to GEO
20.499.6GSM284392Arabidopsis GCE1GSE11262Expression data from Arabidopsis Seed Compartments at the Globular Embryo Stage.Link to GEO
18.699.5GSM311279Laser capture microdissected (LCM) chalazal endosperm at the pre-globular stage, biological replicate 1GSE12402Expression data from Arabidopsis seed compartments at the pre-globular stageLink to GEO
17.899.5GSM205430met1-3_leaf_fourth-selfed generation_rep02GSE8279Transgenerational Stability of the Arabidopsis Epigenome Is Coordinated by CG MethylationLink to GEO
17.099.5GSM205428met1-3_leaf_fourth-selfed generation_rep01GSE8279Transgenerational Stability of the Arabidopsis Epigenome Is Coordinated by CG MethylationLink to GEO
13.299.4GSM133762Lindsey_1-14_torpedo-root_Rep1_ATH1GSE5730Transcriptional profiling of laser-capture micro-dissected embryonic tissuesLink to GEO
12.599.3GSM311280Laser capture microdissected (LCM) chalazal endosperm at the pre-globular stage, biological replicate 2GSE12402Expression data from Arabidopsis seed compartments at the pre-globular stageLink to GEO
12.299.3E-MEXP-1725-raw-cel-1669614623
12.199.3GSM133766Lindsey_1-18_torpedo-root_Rep3_ATH1GSE5730Transcriptional profiling of laser-capture micro-dissected embryonic tissuesLink to GEO
11.499.3GSM205364met1-3_leaf_second-selfed generation_rep01GSE8279Transgenerational Stability of the Arabidopsis Epigenome Is Coordinated by CG MethylationLink to GEO
11.199.2GSM205426met1-3_leaf_second-selfed generation_rep02GSE8279Transgenerational Stability of the Arabidopsis Epigenome Is Coordinated by CG MethylationLink to GEO
11.099.2E-MEXP-1725-raw-cel-1669614634
10.299.2GSM284394Arabidopsis GCE3GSE11262Expression data from Arabidopsis Seed Compartments at the Globular Embryo Stage.Link to GEO
9.299.1E-MEXP-98-raw-cel-320188914
8.999.0E-MEXP-1725-raw-cel-1669614562
8.799.0GSM134208Murray_3-4_D7-GROWTH_Rep1_ATH1GSE5750Growth of suspension-cultured cellsLink to GEO

Biological processes inferred to relate to the module

SFGenesGO IDProcess NameLink to AmiGO
0.0512GO:0009585The sequence of reactions within a cell required to convert absorbed photons from red or far-red light into a molecular signal; the red, far-red light range is defined as having a wavelength within the range 660-730 nm.Link to AmiGO
0.0472GO:0010017The series of molecular signals initiated upon sensing by photoreceptor molecules of red light or far red light. Red light is electromagnetic radiation of wavelength of 580-700nm. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.Link to AmiGO
0.0432GO:0009911Any process that activates or increases the frequency, rate or extent of flower development.Link to AmiGO

KEGG PATHWAY inferred to related to the module

SFGenesKEGG IDPathway nameLink to KEGG
0.043200510N-Glycan biosynthesisLink to KEGG PATHWAY
0.018103420Nucleotide excision repairLink to KEGG PATHWAY
0.013100010Glycolysis / GluconeogenesisLink to KEGG PATHWAY

Inter-species module comparison

Select a plant to compare co-expressed genes between species.
Glycine_max
Hordeum_vulgare
Oryza_sativa
Populus_trichocarpa
Triticum_aestivum
Vitis_vinifera
Zea_mays



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