Co-expression analysis

Gene ID At4g10060
Gene name catalytic/ glucosylceramidase
Module size 59 genes
NF 0.37
%ile 50.6

Co-expression network

pink confeito: Transcription factor, green bicone: Binding protein, red cone: Enzyme protein, blue sphere: Other protein
large node: VF over 0.50, middle node: over 0.25, small node: below 0.25

Co-expressed genes

Click gene/probe ID to show a list of genes that are co-expressed with the gene.

VF %ile CC Gene ID Repr. ID Gene name Func. O.I. H.G. S.X. Other DB
1.00100.01.00At4g10060826597catalytic/ glucosylceramidaseF:catalytic activity, glucosylceramidase activity;P:glucosylceramide catabolic process, sphingolipid metabolic process;C:vacuole;BMPOAO.I.H.G.S.X.
0.6579.60.89At5g22620832325phosphoglycerate/bisphosphoglycerate mutase family proteinF:catalytic activity;P:metabolic process;C:chloroplast;BOMFPAO.I.H.G.S.X.
0.6378.10.87At1g61180842411disease resistance protein (CC-NBS-LRR class), putativeF:protein binding, ATP binding;P:N-terminal protein myristoylation, defense response, apoptosis;C:plasma membrane;PMBOFAO.I.H.G.S.X.
0.6378.10.89At3g26070822204plastid-lipid associated protein PAP / fibrillin family proteinF:structural molecule activity;P:biological_process unknown;C:chloroplast thylakoid membrane, chloroplast, plastoglobule;PBOO.I.H.G.S.X.
0.6277.30.91At5g42310834236pentatricopeptide (PPR) repeat-containing proteinF:unknown;P:unknown;C:chloroplast;POMFBAO.I.H.G.S.X.
0.6075.70.88At5g58140835926PHOT2 (PHOTOTROPIN 2)Membrane-bound protein serine/threonine kinase that functions as blue light photoreceptor in redundancy with PHO1. Involved in stomatal opening, chloroplast movement and phototropism. Mediates blue light-induced growth enhancements. PHOT1 and PHOT2 mediate blue light-dependent activation of the plasma membrane H+-ATPase in guard cell protoplasts. PHOT2 possesses two LOV (LOV1 and LOV2, for light-oxygen-voltage-sensing) domains involved in FMN-binding and a C-terminus forming a serine/threonine kinase domain. LOV2 acts as an inhibitor of phototropin kinase in the dark, and light cancels the inhibition through cysteine-FMN adduct formation. LOV1 in contrast acts as an attenuator of photoactivation. Localized to the Golgi apparatus under the induction of blue light.O.I.H.G.S.X.
0.5570.60.89At3g25690822157CHUP1 (CHLOROPLAST UNUSUAL POSITIONING 1)actin binding protein required for normal chloroplast positioningO.I.H.G.S.X.
0.5267.40.89At4g01800827922preprotein translocase secA subunit, putativeF:protein binding, ATP binding;P:intracellular protein transport, protein targeting, protein import;C:chloroplast stroma, chloroplast, chloroplast envelope;OBPMAO.I.H.G.S.X.
0.5267.40.89At5g35170833471adenylate kinase family proteinF:nucleobase, nucleoside, nucleotide kinase activity, nucleotide kinase activity, phosphotransferase activity, phosphate group as acceptor, adenylate kinase activity, ATP binding;P:nucleobase, nucleoside, nucleotide and nucleic acid metabolic process, anaerobic respiration, nucleotide metabolic process;C:chloroplast thylakoid membrane, chloroplast, chloroplast envelope;BOMFPAO.I.H.G.S.X.
0.5166.30.87At5g07240830615IQD24 (IQ-domain 24)F:calmodulin binding;P:biological_process unknown;C:unknown;PMOBO.I.H.G.S.X.
0.5166.30.88At4g33500829488protein phosphatase 2C-related / PP2C-relatedF:protein serine/threonine phosphatase activity, catalytic activity;P:unknown;C:chloroplast;MOBFPAVO.I.H.G.S.X.
0.5065.30.89At1g54350841876ABC transporter family proteinF:ATPase activity, coupled to transmembrane movement of substances;P:transport;C:chloroplast;BOMFAPVO.I.H.G.S.X.
0.5065.30.87At3g53920824559SIGC (RNA POLYMERASE SIGMA-SUBUNIT C)Encodes a sigma-like transcription factor, Sigma 3 (SIG3 or SIGC). As a subunit of chloroplast RNA polymerase, SIG3 confers the ability to recognize promoter sequences on the core enzyme. SIG3 transcribes specifically the psbN gene in plastids.O.I.H.G.S.X.
0.4862.50.88At1g01790837332KEA1 (K EFFLUX ANTIPORTER 1)K efflux antiporter KEA1O.I.H.G.S.X.
0.4761.20.90At1g17220838293FUG1 (fu-gaeri1)Encodes a chloroplast localized protein with similarity to translation initiation factor 2. Can complement loss of INFB in E.coli suggesting FUG1 does function as a translation initiation factor in vivo. Identified as a suppressor of the leaf variegation mutant var2-6. Suppression is only seen in hypomorphs as complete loss of function alleles are embryo lethal.O.I.H.G.S.X.
0.4659.80.88At4g02260828096RSH1 (RELA-SPOT HOMOLOG 1)F:catalytic activity;P:response to wounding;C:chloroplast;BOPMAFVO.I.H.G.S.X.
0.4659.80.87At5g04140830292GLU1 (GLUTAMATE SYNTHASE 1)Encodes a gene whose sequence is similar to ferredoxin dependent glutamate synthase (Fd-GOGAT). Expression in leaves is induced by light and sucrose. Proposed to be involved in photorespiration and nitrogen assimilation.O.I.H.G.S.X.
0.4659.80.87At1g23400838948CAF2Promotes the splicing of chloroplast group II introns.O.I.H.G.S.X.
0.4558.30.87At5g59750836096riboflavin biosynthesis protein, putativeF:3,4-dihydroxy-2-butanone-4-phosphate synthase activity, GTP cyclohydrolase II activity;P:riboflavin biosynthetic process;C:chloroplast;BOFAPO.I.H.G.S.X.
0.4558.30.87At3g14650820693CYP72A11putative cytochrome P450O.I.H.G.S.X.
0.4558.30.88At5g50920835165CLPC1Encodes a protein that is similar to ATP-dependent Clp protease ATP-binding subunit / ClpC. Involved in protein import into the chloroplast. May provide ATP source that drives the TIC (Translocon at the Inner envelope membrane of Chloroplasts) translocation machinery.O.I.H.G.S.X.
0.4457.20.88At2g23390816871-F:molecular_function unknown;P:biological_process unknown;C:unknown;OBPO.I.H.G.S.X.
0.4152.40.88At4g30993829225unknown proteinF:molecular_function unknown;P:biological_process unknown;C:endomembrane system;PO.I.H.G.S.X.
0.4152.40.88At5g48790834937unknown proteinF:molecular_function unknown;P:biological_process unknown;C:chloroplast;PBOO.I.H.G.S.X.
0.4152.40.87At1g67840843110CSK (CHLOROPLAST SENSOR KINASE)Encodes a chloroplast sensor kinase (CSK) that shares common ancestors with cyanobacterial histidine sensor kinases. CSK is synthesised in the cytosol and imported into the chloroplast as a protein precusor. CSK is autophosphorylated and required for control of transcription of chloroplast genes by the redox state of an electron carrier connecting photosystems I and II.O.I.H.G.S.X.
0.4152.40.88At3g16000820845MFP1 (MAR BINDING FILAMENT-LIKE PROTEIN 1)encodes a DNA-binding protein that binds to plastid DNA non-specifically and is associated with nucleoids and thylakoid membranes. The expression of the gene is correlated with the development of thylakoid membranes.O.I.H.G.S.X.
0.4152.40.88At5g60600836181HDS (4-HYDROXY-3-METHYLBUT-2-ENYL DIPHOSPHATE SYNTHASE)Encodes a chloroplast-localized hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) synthase (HDS), catalyzes the formation of HMBPP from 2-C-methyl-D-erythrytol 2,4-cyclodiphosphate (MEcPP). The HDS enzyme controls the penultimate steps of the biosynthesis of IPP and dimethylallyl diphosphate (DMAPP) via the MEP pathway and may serve as a metabolic control point for SA-mediated disease resistance. In the light, the electrons required for the reaction catalyzed by HDS are directly provided by the electron flow from photosynthesis via ferredoxin. In the dark however, the enzyme requires an electron shuttle: ferredoxin-NADP+ reductase.O.I.H.G.S.X.
0.4050.80.87At3g10230820185LYC (LYCOPENE CYCLASE)Encodes a protein with lycopene β-cyclase activity. This enzyme uses the linear, symmetrical lycopene as substrate. However, unlike the ε-cyclase which adds only one ring, the β-cyclase introduces a ring at both ends of lycopene to form the bicyclic β-carotene.O.I.H.G.S.X.
0.3948.40.89At3g43540823446unknown proteinF:molecular_function unknown;P:biological_process unknown;C:chloroplast;BOPO.I.H.G.S.X.
0.3846.70.88At5g08650830766GTP-binding protein LepA, putativeF:GTP binding, translation elongation factor activity, GTPase activity;P:unknown;C:chloroplast;BOMFPAO.I.H.G.S.X.
0.3643.60.88At3g61080825280fructosamine kinase family proteinF:kinase activity;P:biological_process unknown;C:mitochondrion, chloroplast;BOMFPAO.I.H.G.S.X.
0.3541.60.87At3g19720821509ARC5 (ACCUMULATION AND REPLICATION OF CHLOROPLAST 5)Encodes a novel chloroplast division protein. Mutants of exhibit defects in chloroplast constriction, have enlarged, dumbbell-shaped chloroplasts. The ARC5 gene product shares similarity with the dynamin family of GTPases, which mediate endocytosis, mitochondrial division, and other organellar fission and fusion events in eukaryotes. Phylogenetic analysis showed that ARC5 is related to a group of dynamin-like proteins unique to plants. A GFPARC5 fusion protein localizes to a ring at the chloroplast division site. Chloroplast import and protease protection assays indicate that the ARC5 ring is positioned on the outer surface of the chloroplast. Facilitates separation of the two daughter chloroplasts.O.I.H.G.S.X.
0.3541.60.88At4g29750829097RNA bindingF:RNA binding;P:unknown;C:chloroplast;PMOFAO.I.H.G.S.X.
0.3439.80.88At3g20930821642RNA recognition motif (RRM)-containing proteinF:RNA binding, nucleotide binding, nucleic acid binding;P:biological_process unknown;C:chloroplast;MPFOBAO.I.H.G.S.X.
0.3439.80.88At1g35340840423ATP-dependent protease La (LON) domain-containing proteinF:ATP-dependent peptidase activity;P:ATP-dependent proteolysis;C:chloroplast;BOPFMO.I.H.G.S.X.
0.3439.80.88At3g10970820268haloacid dehalogenase-like hydrolase family proteinF:hydrolase activity, catalytic activity;P:metabolic process;C:chloroplast;BOPAMFO.I.H.G.S.X.
0.3439.80.90At5g35790833559G6PD1 (GLUCOSE-6-PHOSPHATE DEHYDROGENASE 1)Encodes a plastidic glucose-6-phosphate dehydrogenase that is sensitive to reduction by DTT and whose mRNA is more prevalent in developing organs but absent in the root.O.I.H.G.S.X.
0.3235.70.88At2g03390814868uvrB/uvrC motif-containing proteinF:DNA binding, nuclease activity;P:nucleotide-excision repair;C:chloroplast;OBMFPO.I.H.G.S.X.
0.2930.30.87At1g31800840067CYP97A3 (CYTOCHROME P450-TYPE MONOOXYGENASE 97A3)Encodes a protein with β-ring carotenoid hydroxylase activity.O.I.H.G.S.X.
0.2830.30.87At5g17230831587phytoene synthase (PSY) / geranylgeranyl-diphosphate geranylgeranyl transferaseEncodes phytoene synthase.O.I.H.G.S.X.
0.2830.30.88At5g53580835440aldo/keto reductase family proteinF:oxidoreductase activity, aldo-keto reductase activity;P:oxidation reduction;C:chloroplast;BOMFPAO.I.H.G.S.X.
0.2830.30.88At4g15560827230CLA1 (CLOROPLASTOS ALTERADOS 1)Encodes a protein with 1-deoxyxylulose 5-phosphate synthase activity involved in the MEP pathway. It is essential for chloroplast development in ArabidopsisO.I.H.G.S.X.
0.2830.30.88At2g30950817646VAR2 (VARIEGATED 2)Metalloprotease that functions in thylakoid membrane biogenesis. Involved in the repair of PSII following damaged incurred during photoinhibition. Forms a complex with VAR1. Mutants show a variegated phenotype, which decreases during development. Transcript and protein levels increase with light intensity.O.I.H.G.S.X.
0.2726.20.87At2g38330818413MATE efflux family proteinF:drug transporter activity, antiporter activity, transporter activity;P:multidrug transport;C:chloroplast, membrane;BOPAFMO.I.H.G.S.X.
0.2726.20.89At1g32160840108unknown proteinF:molecular_function unknown;P:biological_process unknown;C:chloroplast;PBOO.I.H.G.S.X.
0.2726.20.87At1g15730838142PRLI-interacting factor L, putativeF:unknown;P:unknown;C:unknown;OBMFPAVO.I.H.G.S.X.
0.2726.20.87At5g19220832042APL1 (ADP GLUCOSE PYROPHOSPHORYLASE LARGE SUBUNIT 1)Encodes the large subunit of ADP-glucose pyrophosphorylase which catalyzes the first, rate limiting step in starch biosynthesis. The large subunit plays a regulatory role whereas the small subunit (ApS) is the catalytic isoform. Four isoforms (ApL1-4) have been identified. ApL1 is the major large subunit isoform present in leaves. Mutational analysis of APS1 suggests that APL1 and APL2 can compensate for loss of APS1 catalytic activity,suggesting both have catalytic as well as regulatory functions.O.I.H.G.S.X.
0.2726.20.87At4g37930829949SHM1 (SERINE TRANSHYDROXYMETHYLTRANSFERASE 1)Encodes a protein with mitochondrial serine hydroxymethyltransferase activity, which functions in the photorespiratory pathway, catalyzes the conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. Involved in controlling cell damage caused by abiotic stress, such as high light and salt and the hypersensitive defense response of plants.O.I.H.G.S.X.
0.2522.60.87At5g27560832816unknown proteinF:molecular_function unknown;P:biological_process unknown;C:chloroplast;OBPO.I.H.G.S.X.
0.2522.60.88At1g08540837376SIG2 (RNA POLYMERASE SIGMA SUBUNIT 2)Enodes a subunit of chloroplast RNA polymerase, confers the ability to recognize promoter sequences on the core enzyme. SIG1 is induced by red and blue light.O.I.H.G.S.X.
0.2522.60.88At1g12800837836S1 RNA-binding domain-containing proteinF:RNA binding;P:unknown;C:chloroplast;BOMFPAVO.I.H.G.S.X.
0.2420.70.87At1g23310838940GGT1 (GLUTAMATE:GLYOXYLATE AMINOTRANSFERASE)Identified by cloning the gene that corresponded to a purified protein having glyoxylate aminotransferase activity. Localized to the peroxisome and thought to be involved in photorespiration/ metabolic salvage pathway.O.I.H.G.S.X.
0.2319.30.88At5g4642083468516S rRNA processing protein RimM familyF:ribosome binding, nucleotidyltransferase activity;P:metabolic process, rRNA processing, ribosome biogenesis;C:chloroplast;BOMFPO.I.H.G.S.X.
0.2319.30.88At5g36700833635PGLP1 (2-PHOSPHOGLYCOLATE PHOSPHATASE 1)F:phosphoglycolate phosphatase activity;P:metabolic process;C:chloroplast stroma, chloroplast;BOMFAPO.I.H.G.S.X.
0.2217.50.87At1g32060840098PRK (PHOSPHORIBULOKINASE)F:protein binding, phosphoribulokinase activity, ATP binding;P:response to cold, defense response to bacterium, peptidyl-cysteine S-nitrosylation, biosynthetic process;C:in 8 components;BPOMFAVO.I.H.G.S.X.
0.2115.80.87At1g56500842103haloacid dehalogenase-like hydrolase family proteinF:hydrolase activity, oxidoreductase activity, catalytic activity;P:metabolic process, cell redox homeostasis;C:chloroplast, chloroplast stroma;BOMPAFVO.I.H.G.S.X.
0.1912.70.88At1g08520837374CHLDF:magnesium chelatase activity, nucleoside-triphosphatase activity, nucleotide binding, ATP binding;P:chlorophyll biosynthetic process;C:magnesium chelatase complex, chloroplast;MOBFPVAO.I.H.G.S.X.
0.1912.70.87At3g23700821951S1 RNA-binding domain-containing proteinF:RNA binding;P:response to cold;C:chloroplast stroma, nucleus, chloroplast;BOPMFAO.I.H.G.S.X.

Click More genes

Link to AtGenExpress Visualization Tool

Specific experiments for the module

Std2 GX %ile GSM ID Assay name GSE ID Experiment title Link to GEO
71.199.9GSM133760Lindsey_1-12_heart-stage-root_Rep3_ATH1GSE5730Transcriptional profiling of laser-capture micro-dissected embryonic tissuesLink to GEO
52.799.8GSM253647Col-0 3GSE10039Low_Mo_Arabidopsis_mapping_MOT1Link to GEO
52.799.8GSM253649Col-0-2GSE10039Low_Mo_Arabidopsis_mapping_MOT1Link to GEO
51.199.8GSM143300Ts_genomic_hyb_3GSE6203Rus_etal_High_Na_Arabidopsis_accessions_mapping_HKT1Link to GEO
48.199.8GSM143302Ts_genomic_hyb_1GSE6203Rus_etal_High_Na_Arabidopsis_accessions_mapping_HKT1Link to GEO
46.799.8GSM253648Col-0-1GSE10039Low_Mo_Arabidopsis_mapping_MOT1Link to GEO
46.699.8GSM253646Low_Mo_seg_pool_Ler_col_F2GSE10039Low_Mo_Arabidopsis_mapping_MOT1Link to GEO
46.299.8GSM253650Ler 3GSE10039Low_Mo_Arabidopsis_mapping_MOT1Link to GEO
45.899.8GSM143301Ts_genomic_hyb_2GSE6203Rus_etal_High_Na_Arabidopsis_accessions_mapping_HKT1Link to GEO
45.499.8GSM205430met1-3_leaf_fourth-selfed generation_rep02GSE8279Transgenerational Stability of the Arabidopsis Epigenome Is Coordinated by CG MethylationLink to GEO
44.099.8GSM143299High_Na_seg_pool_ts_col_F2GSE6203Rus_etal_High_Na_Arabidopsis_accessions_mapping_HKT1Link to GEO
43.999.8GSM143298Low_Na_seg_pool_ts_col_F2GSE6203Rus_etal_High_Na_Arabidopsis_accessions_mapping_HKT1Link to GEO
43.099.8GSM143306High_Na_seg_pool_tsu_col_F2GSE6203Rus_etal_High_Na_Arabidopsis_accessions_mapping_HKT1Link to GEO
42.199.8GSM253645High_Mo_seg_pool_Ler_col_F2GSE10039Low_Mo_Arabidopsis_mapping_MOT1Link to GEO
42.099.8GSM143307Low_Na_seg_pool_tsu_col_F2GSE6203Rus_etal_High_Na_Arabidopsis_accessions_mapping_HKT1Link to GEO
41.199.8GSM253651Ler 1GSE10039Low_Mo_Arabidopsis_mapping_MOT1Link to GEO
40.599.8GSM205428met1-3_leaf_fourth-selfed generation_rep01GSE8279Transgenerational Stability of the Arabidopsis Epigenome Is Coordinated by CG MethylationLink to GEO
40.299.8GSM143310Tsu_genomic_hyb_1GSE6203Rus_etal_High_Na_Arabidopsis_accessions_mapping_HKT1Link to GEO
40.199.8GSM143309Tsu_genomic_hyb_2GSE6203Rus_etal_High_Na_Arabidopsis_accessions_mapping_HKT1Link to GEO
39.499.8GSM143308Tsu_genomic_hyb_3GSE6203Rus_etal_High_Na_Arabidopsis_accessions_mapping_HKT1Link to GEO
37.499.7GSM253652Ler 2GSE10039Low_Mo_Arabidopsis_mapping_MOT1Link to GEO
36.699.7GSM205364met1-3_leaf_second-selfed generation_rep01GSE8279Transgenerational Stability of the Arabidopsis Epigenome Is Coordinated by CG MethylationLink to GEO
34.199.7GSM205426met1-3_leaf_second-selfed generation_rep02GSE8279Transgenerational Stability of the Arabidopsis Epigenome Is Coordinated by CG MethylationLink to GEO
29.899.7GSM270870Arabidopsis cell culture, 4 h_response to phytoprostane A1_rep3GSE10719Response of Arabidopsis cell culture to phytoprostane A1Link to GEO
22.599.6GSM205435Col_ leaf_ wildtype_rep02GSE8279Transgenerational Stability of the Arabidopsis Epigenome Is Coordinated by CG MethylationLink to GEO
20.799.6GSM270868Arabidopsis cell culture, 4 h_response to phytoprostane A1_rep2GSE10719Response of Arabidopsis cell culture to phytoprostane A1Link to GEO
18.499.5GSM284389Arabidopsis GMPE2GSE11262Expression data from Arabidopsis Seed Compartments at the Globular Embryo Stage.Link to GEO
17.999.5GSM184556Whole roots 2hr KNO3 treated then incubated in protoplast-generating solution minus enzymes, biological rep2GSE7631Cell-specific nitrogen responses in the Arabidopsis rootLink to GEO
11.499.3GSM184537Whole roots 2hr KCl control treated then frozen, biological rep1GSE7631Cell-specific nitrogen responses in the Arabidopsis rootLink to GEO
10.799.2GSM184551Whole roots 2hr KCl control treated then incubated in protoplast-generating solution minus enzymes, biological rep1GSE7631Cell-specific nitrogen responses in the Arabidopsis rootLink to GEO
10.699.2GSM226530LCOLUMELLASBGSE8934A high resolution organ expression map reveals novel expression patterns and predicts cellular functionLink to GEO
9.899.1GSM311275Laser capture microdissected (LCM) micropylar endosperm at the pre-globular stage, biological replicate 1GSE12402Expression data from Arabidopsis seed compartments at the pre-globular stageLink to GEO
8.799.0GSM205432Col_ leaf_ wildtype_rep01GSE8279Transgenerational Stability of the Arabidopsis Epigenome Is Coordinated by CG MethylationLink to GEO

Biological processes inferred to relate to the module

SFGenesGO IDProcess NameLink to AmiGO
0.0652GO:0009902The process by which chloroplasts in photosynthetic cells migrate toward illuminated sites to optimize photosynthesis and move away from excessively illuminated areas to protect the photosynthetic machinery.Link to AmiGO
0.0653GO:0009853A light-dependent catabolic process occurring concomitantly with photosynthesis in plants (especially C3 plants) whereby dioxygen (O2) is consumed and carbon dioxide (CO2) is evolved. The substrate is glycolate formed in large quantities in chloroplasts from 2-phosphoglycolate generated from ribulose 1,5-bisphosphate by the action of ribulose-bisphosphate carboxylase; the glycolate enters the peroxisomes where it is converted by glycolate oxidase to glyoxylate which undergoes transamination to glycine. This then passes into the mitochondria where it is decarboxylated forming one molecule of serine for every two molecules of glycine. This pathway also exists in photosynthetic bacteria.Link to AmiGO
0.0612GO:0019288The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate by the mevalonate-independent pathway. Isopentenyl diphosphate (IPP) is the fundamental unit in isoprenoid biosynthesis and is biosynthesized from pyruvate and glyceraldehyde 3-phosphate via intermediates, including 1-deoxy-D-xylulose 5-phosphate.Link to AmiGO

KEGG PATHWAY inferred to related to the module

SFGenesKEGG IDPathway nameLink to KEGG
0.049200906Carotenoid biosynthesisLink to KEGG PATHWAY
0.040200900Terpenoid backbone biosynthesisLink to KEGG PATHWAY
0.032401062Biosynthesis of terpenoids and steroidsLink to KEGG PATHWAY

Inter-species module comparison

Select a plant to compare co-expressed genes between species.

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